Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Pengguihang Zeng"'
Autor:
Xiuxiao Tang, Pengguihang Zeng, Kezhi Liu, Li Qing, Yifei Sun, Xinyi Liu, Lizi Lu, Chao Wei, Jia Wang, Shaoshuai Jiang, Jun Sun, Wakam Chang, Haopeng Yu, Hebing Chen, Jiaguo Zhou, Chengfang Xu, Lili Fan, Yi-Liang Miao, Junjun Ding
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract CCCTC-binding factor (CTCF), a ubiquitously expressed and highly conserved protein, is known to play a critical role in chromatin structure. Post-translational modifications (PTMs) diversify the functions of protein to regulate numerous cell
Externí odkaz:
https://doaj.org/article/faa4b4d14dbe448096a8ea86944969cd
Autor:
Jun Sun, Jiale Qu, Cai Zhao, Xinyao Zhang, Xinyu Liu, Jia Wang, Chao Wei, Xinyi Liu, Mulan Wang, Pengguihang Zeng, Xiuxiao Tang, Xiaoru Ling, Li Qing, Shaoshuai Jiang, Jiahao Chen, Tara S. R. Chen, Yalan Kuang, Jinhang Gao, Xiaoxi Zeng, Dongfeng Huang, Yong Yuan, Lili Fan, Haopeng Yu, Junjun Ding
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Understanding intracellular phase separation is crucial for deciphering transcriptional control, cell fate transitions, and disease mechanisms. However, the key residues, which impact phase separation the most for protein phase separation fu
Externí odkaz:
https://doaj.org/article/e247857cd6f6444bb354b68e462cbba0
Autor:
Xiaona Huang, Chao Wei, Fenjie Li, Lumeng Jia, Pengguihang Zeng, Jiahe Li, Jin Tan, Tuanfeng Sun, Shaoshuai Jiang, Jia Wang, Xiuxiao Tang, Qingquan Zhao, Bin Liu, Limin Rong, Cheng Li, Junjun Ding
Publikováno v:
Protein & Cell, Vol 10, Iss 10, Pp 709-725 (2019)
ABSTRACT Polycomb group (PcG) ring finger protein 6 (PCGF6), though known as a member of the transcription-repressing complexes, PcG, also has activation function in regulating pluripotency gene expression. However, the mechanism underlying the activ
Externí odkaz:
https://doaj.org/article/f1662bece80242d6a6e8ffd5d9627afa
Autor:
Chao Wei, Lumeng Jia, Xiaona Huang, Jin Tan, Mulan Wang, Jing Niu, Yingping Hou, Jun Sun, Pengguihang Zeng, Jia Wang, Li Qing, Lin Ma, Xinyi Liu, Xiuxiao Tang, Fenjie Li, Shaoshuai Jiang, Jingxin Liu, Tingting Li, Lili Fan, Yujie Sun, Juntao Gao, Cheng Li, Junjun Ding
Publikováno v:
Cell Research. 32:744-760
Chromatin is spatially organized into three-dimensional structures at different levels including A/B compartments, topologically associating domains and loops. The canonical CTCF-mediated loop extrusion model can explain the formation of loops. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::943d6d2bbd7df1459d2ed7f23b552251
https://doi.org/10.1038/s41422-022-00676-0
https://doi.org/10.1038/s41422-022-00676-0
Autor:
Jiahao Chen, Jingxin Liu, Pengguihang Zeng, Cai Zhao, Xinyi Liu, Jun Sun, Jia Wang, Peihang Fang, Wenjie Chen, Junjun Ding
Publikováno v:
Biochemical and biophysical research communications. 613
Estrogen (E2) is crucial for the development of breast cancer caused by BRCA1 mutation, and can increase the DNA damage in BRCA1-deficient cells. However, the mechanisms through which BRCA1 deficiency and E2 synergistically induce DNA damage remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f9673f46a3c25af2dc3a6f39579ea4
https://pubmed.ncbi.nlm.nih.gov/35561581
https://pubmed.ncbi.nlm.nih.gov/35561581
Autor:
Jingran Zhang, Pengguihang Zeng, Junfeng Su, Zhou Songyang, Junjie Pang, Xiya Zhang, Yuanyan Xiong, Junjun Ding, Guang Shi, Dan Liu, Quanyuan He, Jingwen Wang, Junjiu Huang, Wenbin Ma, Yaofu Bai
Publikováno v:
Proteincell. 13(10)
Understanding the regulatory networks for germ cell fate specification is necessary to developing strategies for improving the efficiency of germ cell production in vitro. In this study, we developed a coupled screening strategy that took advantage o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ee273670e4e0b68dafa9c34e2f59c3
https://pubmed.ncbi.nlm.nih.gov/34731408
https://pubmed.ncbi.nlm.nih.gov/34731408
Autor:
Haopeng Yu, Junjun Ding, Shaoshuai Jiang, Cai Zhao, Xiaoxi Zeng, Lumeng Jia, Cheng Li, Wei Zhang, Jianlong Wang, Yangyinhui Yu, Jia Wang, Qian Ma, Xianglin Huang, Yujie Sun, Xinyi Liu, Fenjie Li, Miguel Fidalgo, Jun Sun, Yingping Hou, Jiahao Chen, Yilong Chen, Yi-Liang Miao, Pengguihang Zeng, Danya Wu, Diana Guallar
Publikováno v:
Cell stem cell. 28(10)
Topological-associated domains (TADs) are thought to be relatively stable across cell types, although some TAD reorganization has been observed during cellular differentiation. However, little is known about the mechanisms through which TAD reorganiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7263228ffb6e293a66d69f515baa0c02
https://pubmed.ncbi.nlm.nih.gov/34624226
https://pubmed.ncbi.nlm.nih.gov/34624226