Zobrazeno 1 - 10
of 1 596
pro vyhledávání: '"Pengfei XU"'
Autor:
Peng Pan, Michael Zoberman, Pengsong Zhang, Sharanja Premachandran, Sanjana Bhatnagar, Pallavi P. Pilaka-Akella, William Sun, Chengyin Li, Charlotte Martin, Pengfei Xu, Zefang Zhang, Ryan Li, Wesley Hung, Hua Tang, Kailynn MacGillivray, Bin Yu, Runze Zuo, Karinna Pe, Zhen Qin, Shaojia Wang, Ang Li, W. Brent Derry, Mei Zhen, Arneet L. Saltzman, John A. Calarco, Xinyu Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The nematode Caenorhabditis elegans is widely employed as a model organism to study basic biological mechanisms. However, transgenic C. elegans are generated by manual injection, which remains low-throughput and labor-intensive, limiting the
Externí odkaz:
https://doaj.org/article/b503551c7f214a86a2d6655e303a67ea
Autor:
Pengfei Xu, Yingjie Zhang, Junyan Guo, Huihui Li, Sandra Konrath, Peng Zhou, Liming Cai, Haojie Rao, Hong Chen, Jian Lin, Zhao Cui, Bingyang Ji, Jianwei Wang, Nailin Li, De-Pei Liu, Thomas Renné, Miao Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Factor XII (FXII) is the zymogen of the plasma protease FXIIa that activates the intrinsic coagulation pathway and the kallikrein kinin-system. The role of FXII in inflammation has been obscure. Here, we report a single-domain antibody (nano
Externí odkaz:
https://doaj.org/article/af1ffc261c974bac96acdb6aa83394f7
Autor:
Jiawan Wang, Wei Wang, Jiandong Zhang, Fei Xiao, Zeya Li, Pengfei Xu, Haozhou Wang, Heng Du, Siqi Liu, Huili Li, Xuan Zhang, Siqi Chen, Zeyu Gao, Sheng Wang, Jun Wang, Moshi Song
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract The kidney is vulnerable to ischemia and reperfusion (I/R) injury that can be fatal after major surgery. Currently, there are no effective treatments for I/R-induced kidney injury. Trimethylamine N-oxide (TMAO) is a gut-derived metabolite li
Externí odkaz:
https://doaj.org/article/c450d9ec4ab44133a23dde52404da7f9
Autor:
D’Juan T. Farmer, Jennifer E. Dukov, Hung-Jhen Chen, Claire Arata, Jose Hernandez-Trejo, Pengfei Xu, Camilla S. Teng, Robert E. Maxson, J. Gage Crump
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Cranial sutures separate neighboring skull bones and are sites of bone growth. A key question is how osteogenic activity is controlled to promote bone growth while preventing aberrant bone fusions during skull expansion. Using single-cell tr
Externí odkaz:
https://doaj.org/article/64e509a19a1944e79ff640fcdd4c8206
Autor:
Pengfei Xu, Joy C. Yang, Bo Chen, Shu Ning, Xiong Zhang, Leyi Wang, Christopher Nip, Yuqiu Shen, Oleta T. Johnson, Gabriela Grigorean, Brett Phinney, Liangren Liu, Qiang Wei, Eva Corey, Clifford G. Tepper, Hong-Wu Chen, Christopher P. Evans, Marc A. Dall’Era, Allen C. Gao, Jason E. Gestwicki, Chengfei Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract N-Myc is a key driver of neuroblastoma and neuroendocrine prostate cancer (NEPC). One potential way to circumvent the challenge of undruggable N-Myc is to target the protein homeostasis (proteostasis) system that maintains N-Myc levels. Here
Externí odkaz:
https://doaj.org/article/7245d627558b40309015d3fca64f4865
Autor:
Yachen Ji, Xianhui Ding, Lulu Xiao, Min Li, Kangfei Wu, Junfeng Xu, Zuowei Duan, Wen Sun, Pengfei Xu, Xianjun Huang
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 7, Pp 1921-1929 (2024)
Abstract Objectives A higher reperfusion grade after endovascular thrombectomy (EVT) is associated with a good prognosis. However, the effect of the number of retrievals has not yet been investigated in vertebrobasilar occlusion (VBAO). Therefore, th
Externí odkaz:
https://doaj.org/article/3b22a481cfdb443186a748694bbaedc8
Autor:
Jinhang Zhang, Ya Huang, Hong Li, Pengfei Xu, Qinhui Liu, Yang Sun, Zijing Zhang, Tong Wu, Qin Tang, Qingyi Jia, Yan Xia, Ying Xu, Xiandan Jing, Jiahui Li, Li Mo, Wen Xie, Aijuan Qu, Jinhan He, Yanping Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Pregnane X receptor (PXR) has been reported to regulate glycolipid metabolism. The dysfunction of intestinal barrier contributes to metabolic disorders. However, the role of intestinal PXR in metabolic diseases remains largely unknown. Here,
Externí odkaz:
https://doaj.org/article/c585118dd2cb442cb8c2dbc63eae7924
Autor:
Kaiyue Zhou, Zhengliang Xiao, Qi Liu, Xu Wang, Jiaxin Huo, Xiaoqi Wu, Xiaoxiao Zhao, Xiaohan Feng, Baoyi Fu, Pengfei Xu, Yunyun Deng, Wenwen Xiao, Tao Sun, Lin Da
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract T-cell receptor (TCR) detection can examine the extent of T-cell immune responses. Therefore, the article analyzed characteristic data of glioma obtained by DNA-based TCR high-throughput sequencing, to predict the disease with fewer biomarke
Externí odkaz:
https://doaj.org/article/7cfb84388f4d466195a9e296e77d37ec
Publikováno v:
Ecological Indicators, Vol 167, Iss , Pp 112672- (2024)
Urban areas are major sources of carbon emissions, making it crucial to understand their emission characteristics for effective carbon reduction and sustainable development. Using carbon emission data from mainland China (2001–2021), we analyzed th
Externí odkaz:
https://doaj.org/article/ef704906202942d78a9836ab113b3845
Autor:
Cheng Yu, Linan Hu, Qilin Yu, Yulu Ren, Minping Zhang, Lujing Gao, Shiyi Lyu, Junli Wang, Enhua Xiao, Zhu Chen, Quanliang Shang, Pengfei Xu
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Eliciting anti-tumor immune responses and improving the tumor microenvironment crucial for boosting the effectiveness of anti-PD-1 immunotherapy. Tumor-associated macrophages (TAMs), the primary types of immune cells infiltrating tumors, play a criti
Externí odkaz:
https://doaj.org/article/c99a504c4d04475a9f5227a649ea3b6c