Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Peng-Peng Zhu"'
Autor:
Peng-Peng Zhu, Hui-Fang Hung, Natalia Batchenkova, Jonathon Nixon-Abell, James Henderson, Pengli Zheng, Benoit Renvoisé, Song Pang, C Shan Xu, Stephan Saalfeld, Jan Funke, Yuxiang Xie, Fabian Svara, Harald F Hess, Craig Blackstone
Publikováno v:
Human Molecular Genetics
Hum Mol Genet
Hum Mol Genet
Hereditary spastic paraplegias (HSPs) comprise a large group of inherited neurologic disorders affecting the longest corticospinal axons (SPG1–86 plus others), with shared manifestations of lower extremity spasticity and gait impairment. Common aut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2baa4de00e3494a28da7f594bfe0af
https://hdl.handle.net/21.11116/0000-000A-6F6A-421.11116/0000-000A-6F6C-221.11116/0000-000A-F45D-B
https://hdl.handle.net/21.11116/0000-000A-6F6A-421.11116/0000-000A-6F6C-221.11116/0000-000A-F45D-B
Publikováno v:
Sci Signal
Mutations in WASHC5 (also known as KIAA0196) cause autosomal dominant hereditary spastic paraplegia (HSP) type SPG8. WASHC5, commonly called strumpellin, is a core component of the Wiskott-Aldrich syndrome protein and SCAR homologue (WASH) complex th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b37b0033388925ecb1fba80407f1846
https://doi.org/10.1126/scisignal.aau7500
https://doi.org/10.1126/scisignal.aau7500
Publikováno v:
Central Nervous System Agents in Medicinal Chemistry. 18:206-212
Introduction Suicide is still a major event of human mortality worldwide. Yet human suicide prediction, prevention and therapeutic systems at this moment are generally ineffective in the clinic. No diagnostic system is reliable for significantly suic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353434e85d6da73e73b56b6c57e802ab
https://doi.org/10.2174/1871524918666180817093015
https://doi.org/10.2174/1871524918666180817093015
Autor:
Craig Blackstone, Samy Sid Ahmed, Philippe Roingeard, Françoise Porrot, Julien Burlaud-Gaillard, Sonia Amraoui, Ali Amara, Maaran Michael Rajah, Blandine Monel, Julian Buchrieser, Cécile Meunier, Maxime Chazal, Olivier Schwartz, Mohamed Lamine Hafirassou, Quentin Nevers, Peng-Peng Zhu, Nolwenn Jouvenet, Audrey Salles
Publikováno v:
J Virol
The endoplasmic reticulum (ER) is the site for Zika virus (ZIKV) replication and is central to the cytopathic effects observed in infected cells. ZIKV induces the formation of ER-derived large cytoplasmic vacuoles followed by “implosive” cell dea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a92577276cd29467f2b544acbe840924
https://pubmed.ncbi.nlm.nih.gov/31534046
https://pubmed.ncbi.nlm.nih.gov/31534046
Publikováno v:
Central Nervous System Agents in Medicinal Chemistry. 16:231-239
Suicide events and episodes are serious human psychiatric disorders affected by a great number of different environmental/economic factors, early trauma/abuse, human bad living habits, human genomic properties and drug intervention decisions. In orde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d7ae06eec7fbac92f06117a0a42038
https://doi.org/10.2174/1871524916666160210142734
https://doi.org/10.2174/1871524916666160210142734
Publikováno v:
Central nervous system agents in medicinal chemistry. 19(1)
The article entitled “Human Suicide, Modern Diagnosis Assistance and Magic Bullet Discovery”, by Da-Yong Lu, Peng-Peng Zhu, Hong-Ying Wu, Nagendra Sastry Yarla, Bin Xu, Jian Ding, Ajit Varki and Ting-Ren Lu, has been retracted on the request of o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cf2fc90c7bd3458b696cadb67078944
https://pubmed.ncbi.nlm.nih.gov/30644350
https://pubmed.ncbi.nlm.nih.gov/30644350
Publikováno v:
DEStech Transactions on Engineering and Technology Research.
A new chiral catalyst, (R,R)-N,N-bis-(3-tert-butyl-5- chloromethylsalicylaldehyde)-1,2- cyclohexanediamine cobalt(III) acetic acid monohydrate (di-CH2Cl-salen-Co), was synthesized and utilized in racemic epichlorohydrin hydrolytic kinetic resolution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94d28190a2dab9afa15c53086b546774
https://doi.org/10.12783/dtetr/apetc2017/11066
https://doi.org/10.12783/dtetr/apetc2017/11066
Publikováno v:
Human molecular genetics, vol 23, iss 21
Hereditary spastic paraplegias are a large, diverse group of neurological disorders (SPG1-71) with the unifying feature of prominent lower extremity spasticity, owing to a length-dependent axonopathy of corticospinal motor neurons. The most common ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efac5d996e7cb2f37082f7bfd496a63a
https://doi.org/10.1093/hmg/ddu280
https://doi.org/10.1093/hmg/ddu280
Autor:
Peng-Peng Zhu, Benoît Renvoisé, Seonghee Park, Lymarie Maldonado-Báez, Craig Blackstone, Guohua Zhao
Publikováno v:
Experimental cell research. 349(1)
Atlastins are large, membrane-bound GTPases that participate in the fusion of endoplasmic reticulum (ER) tubules to generate the polygonal ER network in eukaryotes. They also regulate lipid droplet size and inhibit bone morphogenetic protein (BMP) si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b6e5fddc6c206922916e466396fa008
https://pubmed.ncbi.nlm.nih.gov/27669642
https://pubmed.ncbi.nlm.nih.gov/27669642
Publikováno v:
Central Nervous System Agents in Medicinal Chemistry. 12:250-253
Adverse side effects or toxicities of a drug were previously regarded as a manifestation of drug's own characterizations, such as the chemical structure and property of a drug. More recently, increasing experimental or clinical data and modern ideas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f1bfc33af28b0a6ee79181ff964e2f9
https://doi.org/10.2174/187152412803760591
https://doi.org/10.2174/187152412803760591