Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Peng-Nien Huang"'
Autor:
Yu-An Kung, Huan-Jung Chiang, Mei-Ling Li, Yu-Nong Gong, Hsin-Ping Chiu, Chuan-Tien Hung, Peng-Nien Huang, Sheng-Yu Huang, Pei-Yu Wang, Tsu-An Hsu, Gary Brewer, Shin-Ru Shih
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Enterovirus infections can cause severe complications, such as poliomyelitis, encephalitis, myocarditis, meningitis, neurological pulmonary edema, and even death. Here, we used genome-wide CRISPR screens to gain new insight into the mechanis
Externí odkaz:
https://doaj.org/article/296ab0bacfe54232b59880a5976bf66c
Autor:
Kuan-Ting Liu, Yu-Nong Gong, Chung-Guei Huang, Peng-Nien Huang, Kar-Yee Yu, Hou-Chen Lee, Sun-Che Lee, Huan-Jung Chiang, Yu-An Kung, Yueh-Te Lin, Mei-Jen Hsiao, Po-Wei Huang, Sheng-Yu Huang, Hsin-Tai Wu, Chih-Ching Wu, Rei-Lin Kuo, Kuan-Fu Chen, Chuan-Tien Hung, Kasopefoluwa Y. Oguntuyo, Christian S. Stevens, Shreyas Kowdle, Hsin-Ping Chiu, Benhur Lee, Guang-Wu Chen, Shin-Ru Shih
Publikováno v:
mSphere, Vol 7, Iss 1 (2022)
ABSTRACT Considering the urgent demand for faster methods to quantify neutralizing antibody titers in patients with coronavirus (CoV) disease 2019 (COVID-19), developing an analytical model or method to replace the conventional virus neutralization t
Externí odkaz:
https://doaj.org/article/2329db479b854b42bcfab73d82950bf4
Autor:
Kuan-Ying A. Huang, Daming Zhou, Elizabeth E. Fry, Abhay Kotecha, Peng-Nien Huang, Shu-Li Yang, Kuo-Chien Tsao, Yhu-Chering Huang, Tzou-Yien Lin, Jingshan Ren, David I. Stuart
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
To date, no therapeutic agents against enterovirus 71, the causative agent of hand, foot and mouth disease, exist. Here, using Cryo-EM Huang et al. characterize two plasmablast-derived plateau-binding neutralizing antibodies conferring effective prot
Externí odkaz:
https://doaj.org/article/4b4769b88b7b49b0ba87e9ad7d89cbcd
Autor:
Yu-Nong Gong, Kuo-Chien Tsao, Mei-Jen Hsiao, Chung-Guei Huang, Peng-Nien Huang, Po-Wei Huang, Kuo-Ming Lee, Yi-Chun Liu, Shu-Li Yang, Rei-Lin Kuo, Kuan-Fu Chen, Yen-Chin Liu, Sheng-Yu Huang, Hsing-I. Huang, Ming-Tsan Liu, Ji-Rong Yang, Cheng-Hsun Chiu, Cheng-Ta Yang, Guang-Wu Chen, Shin-Ru Shih
Publikováno v:
Emerging Microbes and Infections, Vol 9, Iss 1, Pp 1457-1466 (2020)
ABSTRACTTaiwan experienced two waves of imported infections with Coronavirus Disease 2019 (COVID-19). This study aimed at investigating the genomic variation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Taiwan and compared their
Externí odkaz:
https://doaj.org/article/c9f4e2455fd64241a25bf10b7d2d5ec0
Autor:
Chi-Hsin Lee, Peng-Nien Huang, Pharaoh Fellow Mwale, Wei-Chu Wang, Sy-Jye Leu, Sung-Nien Tseng, Shin-Ru Shih, Liao-Chun Chiang, Yan-Chiao Mao, Bor-Yu Tsai, Nhlanhla Benedict Dlamini, Tien-Cuong Nguyen, Chen-Hsin Tsai, Yi-Yuan Yang
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 12967 (2022)
Enterovirus 71 (EV71) is the major etiological agent contributing to the development of hand-foot-mouth disease (HFMD). There are not any global available vaccines or antibody drugs against EV71 released yet. In this study, we perform the virus immun
Externí odkaz:
https://doaj.org/article/05e23aca2bac4c2cb6a1a7881c16a9c6
Publikováno v:
Viruses, Vol 14, Iss 7, p 1560 (2022)
We aimed to review the existing literature on the different types of neutralization assays and international standards for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We comprehensively summarized the serological assays for detectin
Externí odkaz:
https://doaj.org/article/06f80505f32e4d8b92b3595c52657e27
Autor:
Sheng-Yu Huang, Yu-An Kung, Peng-Nien Huang, Sheng-Yun Chang, Yu-Nong Gong, Yi-Ju Han, Huan-Jung Chiang, Kuan-Ting Liu, Kuo-Ming Lee, Chia-Yu Chang, Chia-Ching Chang, Chung-Guei Huang, Shin-Ru Shih
Publikováno v:
mSphere, Vol 6, Iss 2 (2021)
It has been observed that variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are more stable and infectious after storage at −20°C than at 4°C. A SARS-CoV-2 S-D614G variant is currently the most dominant variant in circulati
Externí odkaz:
https://doaj.org/article/3358e70149b94b52b0cf95cea8d29bd8
Autor:
Hsiang-Ching Wang, Hui-Chen Hung, Peng-Nien Huang, Yu-An Kung, Sung-Nien Tseng, Yun-Ming Wang, Shin-Ru Shih, John Tsu-An Hsu
Publikováno v:
Biochemistry and Biophysics Reports, Vol 24, Iss , Pp 100860- (2020)
Frequent outbreaks of enterovirus A71 (EVA71) occur in the Asia-Pacific area, and these are closely associated with severe neurological symptoms in young children. No effective antiviral therapy is currently available for the treatment of EVA71 infec
Externí odkaz:
https://doaj.org/article/ee321dac7414433f8ce0206970c0169b
Autor:
Kuan-Ying A Huang, Peng-Nien Huang, Yhu-Chering Huang, Shu-Li Yang, Kuo-Chien Tsao, Cheng-Hsun Chiu, Shin-Ru Shih, Tzou-Yien Lin
Publikováno v:
PLoS Pathogens, Vol 16, Iss 9, p e1008857 (2020)
An outbreak of the hand-foot-mouth disease with severe neurological cases, mainly caused by the genotype C1 enterovirus A71 (EV-A71), occurred in Taiwan between 2018 and early 2019. In the recent decade, the most dominant EV-A71 genotypes in Taiwan w
Externí odkaz:
https://doaj.org/article/384160c6d511417f916c55e110bbbc2d
Autor:
Peng-Nien Huang
Publikováno v:
Medicine in Microecology, Vol 3, Iss , Pp 100006- (2020)
Enteric viruses can directly infect the mammalian gastrointestinal tract which is home to a diverse community of commensal microorganism. Emerging evidence suggests that certain enteric viruses utilize these microbiotas to promote infection. Multiple
Externí odkaz:
https://doaj.org/article/d3871d38790b4d31a5b348a4f4bc02dc