Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Penelope Roques"'
Autor:
Jordi Perez-Tur, Susanne Froelich, Guy Prihar, Richard Crook, Matt Baker, Karen Duff, Michelle Wragg, Frances Busfield, Corinne Lendon, Robert F. Clark, Penelope Roques, Rebecca A. Fuldner, Janet Johnston, Richard Cowburn, Charlotte Forsell, Karin Axelman, Lena Lilius, Henry Houlden, Eric Karran, Gareth W. Roberts, Martin Rossor, Mark D. Adams, John Hardy, Alison Goate, Lars Lannfelt, Michael Hutton
Publikováno v:
Scopus-Elsevier
A series of mutations has been reported in the presenilin-1 (PS-1) gene which cause early onset Alzheimer's disease (AD). The mutations reported to date have encoded missense mutations which alter residues conserved between PS-1 and the presenilin-2
Autor:
Mike Hutton, Frances Busfield, Michelle Wragg, Richard Crook, Jordi Perez-Tur, Robert F. Clark, Guy Prihar, Helen Phillips, Kristal Wright, Matt Baker, Corinne Lendon, Karen Duff, Alonso Martinez, Henry Houlden, Andy Nichols, Eric Karran, Gareth Roberts, Penelope Roques, Martin Rossor, J. Craig Venter, Mark D. Adams, Robin T. Cline, Cheryl A. Phillips, Rebecca A. Fuldner, John Hardy, Alison Goate
Publikováno v:
Neuroreport. 7(3)
THE presenilin 1 gene has recently been identified as the locus on chromosome 14 which is responsible for a large proportion of early onset, autosomal dominantly inherited Alzheimer's disease (AD). We have elucidated the intron/exon structure of the