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pro vyhledávání: '"Penelope M.S. Clark"'
Plasma insulin, intact proinsulin and 32–33 split proinsulin measured by specific immunoradiometric assays and insulin and C-peptide measured by radioimmunoassay were measured during a constant infusion of glucose test in ten diet-treated subjects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fedc559e6efb8470aa26e6996cfa8d21
https://ora.ox.ac.uk/objects/uuid:11c0a1a3-69a0-494f-ad6f-fef981694bf9
https://ora.ox.ac.uk/objects/uuid:11c0a1a3-69a0-494f-ad6f-fef981694bf9
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 47:200-204
Background Since more than 90% of cortisol is bound to protein, serum free cortisol (SFC) may be a more appropriate marker of adrenal status than total cortisol. However, measurement of SFC is technically difficult and calculated SFC may offer a more
Autor:
Mario Plebani, Stephan K G Grebe, Luca Giovanella, Ulla Feldt-Rasmussen, Penelope M.S. Clark, Frederik A. Verburg
Differentiated thyroid cancer (DTC) is the most common endocrine cancer and its incidence has increased in recent decades. The initial treatment consists of total thyroidectomy followed by ablation of thyroid remnants by radioiodine in most cases. As
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::415defec6a59a9bde2b598d4adbcb50d
http://hdl.handle.net/11577/3230441
http://hdl.handle.net/11577/3230441
Autor:
PD Gluckman, David J.P. Barker, Bernhard H. Breier, Penelope M.S. Clark, Chittaranjan S. Yajnik, Catherine Law, Caroline H.D. Fall, Anand Pandit, A. W. Shiell, Clive Osmond
Publikováno v:
Archives of Disease in Childhood. 73:287-293
OBJECTIVE--To test the hypothesis that reduced fetal growth leads to altered plasma insulin-like growth factor-1 (IGF-1) concentrations in childhood. DESIGN--A follow up study of 4 year old children whose birth weights were recorded, and of 7 year ol
Autor:
Owen M. Edwards, Robert Swinn, Robert Gregory, Victoria Curling, Penelope M.S. Clark, Kevin J. Dalton, Nicholas J. Wareham, Stephen O'Rahilly
Publikováno v:
Diabetes. 44:911-915
Using assays that specifically measure insulin, intact proinsulin, and 32,33 split proinsulin, we examined the β-cell secretory response to an oral glucose tolerance test (OGTT) in 64 women with gestational diabetes mellitus (GDM) and 154 pregnant n
Autor:
Penelope M.S. Clark, Lorna Cox, Kenneth S. Polonsky, JohnS. Yudkin, C. N. Hales, D.K. Nagi, Diane Ostrega
Publikováno v:
Diabetes. 44:437-440
Human proinsulin and 32–33 split proinsulin have been measured in the peripheral circulation by immunoradiometric assays (IRMAs) and have been shown to be elevated in impaired glucose tolerance and non-insulin-dependent diabetes mellitus (NIDDM). T
Autor:
Clive Osmond, Penelope M.S. Clark, Yvonne Stirling, C. N. Hales, David J.P. Barker, Caroline H.D. Fall, T W Meade
Publikováno v:
BMJ. 310:428-432
Objective: To examine whether cardiovascular risk factors in women are related to fetal and infant growth. Design: Follow up study of women born 1923-30 whose birth weights and weights at one year were recorded. Setting: Hertfordshire. Subjects: 297
Autor:
Nicholas J. Wareham, Christopher D. Byrne, D. C. Brown, T. W. M. Wang, Nicholas E. Day, D. R. R. Williams, Christopher R. Palmer, Penelope M.S. Clark, Lorna Cox, C. N. Hales
Publikováno v:
Diabetologia. 37:889-896
Although plasma insulin and triglyceride concentrations are positively correlated in many studies, the relationships between insulin resistance, insulin secretion and hypertriglyceridaemia remain unclear. To study these associations, subjects between
Publikováno v:
Diabetologia. 37:592-596
Recent studies suggest that NIDDM is linked with reduced fetal and infant growth. Observations on malnourished infants and studies of experimental animals exposed to protein energy or protein deficiency in fetal or early neonatal life suggest that th
Publikováno v:
Diabetic Medicine. 10:839-842
The short insulin tolerance test is a simple method of estimating insulin resistance by measuring the rate of fall of blood glucose following the intravenous administration of insulin. To determine its reproducibility, 18 healthy subjects underwent d