Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Penelope J. Noble"'
Autor:
Yu-ling Ma, Rou-Mu Hu, Xinchun Yang, Taiyi Wang, Penelope J. Noble, Robert Wilkins, Clive Ellory, Carolyn Carr, Denis Noble, Jiefu Yang, Weixing Lu, Junhua Zhang, Hongde Hu, Xiaomei Guo, Min Chen, Yang Wu, Meng Wei, Jingyuan Mao, Xiaochang Ma, Ling Qin, Huanlin Wu, Feng Lu, Ying Cao, Sheng Gao, Wanli Gu
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Xin Su Ning (XSN), a China patented and certified multi-herbal medicine, has been available in China since 2005 for treating cardiac ventricular arrhythmia including arrhythmia induced by ischemic heart diseases and viral myocarditis, without adverse
Externí odkaz:
https://doaj.org/article/88aec205a4694cb580e174cb249d9750
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Since the Principle of Biological Relativity was formulated and developed there have been many implementations in a wide range of biological fields. The purpose of this article is to assess the status of the applications of the principle and to clari
Externí odkaz:
https://doaj.org/article/b551b2a39e5146af905ef47704647522
Publikováno v:
Physiome.
We describe a major development of the Shorten et al. (Shorten et al., 2007) model of skeletal muscle electrophysiology, biochemistry, and mechanics. The model was developed by incorporating equations for sarcolemmal transport of calcium ions, includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f33132e85bf1f83394e369308d4a3258
https://doi.org/10.36903/physiome.12885590
https://doi.org/10.36903/physiome.12885590
In an accompanying paper [2], we developed the Shorten [3] model of skeletal muscle by incorporating equations such as surface calcium fluxes. In further research in this paper, we succeeded in reproducing muscle cramp, as well as its prevention and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d4cd87e4825fac1ef848827dc287134
https://doi.org/10.36903/physiome.12871364.v1
https://doi.org/10.36903/physiome.12871364.v1
Autor:
Xiaochang Ma, Penelope J. Noble, Xiaomei Guo, Denis Noble, Huanlin Wu, Jingyuan Mao, Junhua Zhang, Jiefu Yang, Feng Lu, Robert Wilkins, Min Chen, Meng Wei, Hongde Hu, Yu-Ling Ma, Carolyn A. Carr, Yang Wu, Clive Ellory, Ying Cao, Taiyi Wang, Xinchun Yang, Ling Qin, Wanli Gu, Rou-Mu Hu, Sheng Gao, Weixing Lu
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Frontiers in Pharmacology
Frontiers in Pharmacology
Xin Su Ning (XSN), a China patented and certified multi-herbal medicine, has been available in China since 2005 for treating cardiac ventricular arrhythmia including arrhythmia induced by ischemic heart diseases and viral myocarditis, without adverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c54b59fd46b0192d6af0c5552cfa1ef2
https://www.frontiersin.org/article/10.3389/fphar.2020.00600/full
https://www.frontiersin.org/article/10.3389/fphar.2020.00600/full
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Frontiers in Physiology
Frontiers in Physiology
Since the Principle of Biological Relativity was formulated and developed there have been many implementations in a wide range of biological fields. The purpose of this article is to assess the status of the applications of the principle and to clari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b86edf1a37287e66f7525df76ab823ed
https://www.frontiersin.org/article/10.3389/fphys.2019.00827/full
https://www.frontiersin.org/article/10.3389/fphys.2019.00827/full
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e4f3d795e897220c84dd940f862719a
https://doi.org/10.1096/fasebj.2019.33.1_supplement.538.5
https://doi.org/10.1096/fasebj.2019.33.1_supplement.538.5
Autor:
Pierre Fontanaud, Matteo E. Mangoni, Henri Benkemoun, Penelope J. Noble, Denis Noble, Sylvain Richard, Joël Nargeot
OBJECTIVE: The L-type Ca(2+) current (I(Ca,L)) contributes to the generation and modulation of the pacemaker action potential (AP). We investigated facilitation of I(Ca,L) in sino-atrial cells. METHODS: Facilitation was studied in regularly-beating c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d6b01c1d7cc2e71022030bcf5bf195b
https://ora.ox.ac.uk/objects/uuid:b5b78662-7582-4cca-ba41-846dae022717
https://ora.ox.ac.uk/objects/uuid:b5b78662-7582-4cca-ba41-846dae022717
Autor:
Denis Noble, Slavisa Garic, Colin Enticott, David Abramson, David J. Gavaghan, Anna A. Sher, Tom Peachey, Penelope J. Noble
Publikováno v:
Computational Science – ICCS 2008 ISBN: 9783540693833
ICCS (1)
ICCS (1)
Understanding physiological mechanisms underlying the activity of the heart is of great medical importance. Mathematical modeling and numerical simulation have become a widely accepted method of unraveling the underlying mechanism of the heart. Calci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::283abd593e084e53ae2e6b91795432e7
https://ora.ox.ac.uk/objects/uuid:d2e37260-5758-4090-8a36-8a3c8b6a6574
https://ora.ox.ac.uk/objects/uuid:d2e37260-5758-4090-8a36-8a3c8b6a6574
Early development of ionic models for cardiac myocytes, from the pioneering modification of the Hodgkin–Huxley giant squid axon model by Noble to the iconic DiFrancesco–Noble model integrating voltage-gated ionic currents, ion pumps and exchanger
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::040214707af21bbce8ad1d9381660f80
https://ora.ox.ac.uk/objects/uuid:38227495-5377-496b-8699-ca38a1a9ccca
https://ora.ox.ac.uk/objects/uuid:38227495-5377-496b-8699-ca38a1a9ccca