Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Penelope J. Knowles"'
Autor:
David R. Grattan, Penelope J. Knowles, Ana Maria Ornstein, Guillermina Maria Luque, Felicitas Lopez-Vicchi, Damasia Becu-Villalobos, Papillon Gustafson, Sharon R Ladyman
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 34(3)
To study the pathological effects of continuous hyperprolactinemia on food intake mechanisms we used female mice that lack dopamine D2 receptors in lactotropes (lacDrd2KO). These mice had lifelong hyperprolactinemia, increased food intake, and gradua
Autor:
David R. Grattan, Rachael A. Augustine, Zin Khant Aung, Sharon R Ladyman, Penelope J. Knowles
Publikováno v:
Journal of Neuroendocrinology. 31
Pregnancy in rodents is associated with hyperphagia, increased fat deposition, elevated leptin concentrations and insensitivity to the satiety action of leptin. To investigate the hormonal mechanisms involved in the development of this state of pregn
Autor:
Amanda Wyatt, Sharon R Ladyman, Papillon Gustafson, Hollian R Phillipps, Paul LeTissier, Caroline M. Larsen, David R. Grattan, Ilona C. Kokay, Penelope J. Knowles, Rosemary S E Brown, Siew Hoong Yip
Publikováno v:
Brown, R S E, Kokay, I C, Phillipps, H R, Yip, S H, Gustafson, P, Wyatt, A, Larsen, C M, Knowles, P, Ladyman, S R, Le Tissier, P & Grattan, D R 2016, ' Conditional Deletion of the Prolactin Receptor Reveals Functional Subpopulations of Dopamine Neurons in the Arcuate Nucleus of the Hypothalamus ', Journal of Neuroscience, vol. 36, no. 35, pp. 9173-85 . https://doi.org/10.1523/JNEUROSCI.1471-16.2016
UNLABELLED: Tuberoinfundibular dopamine (TIDA) neurons, known as neuroendocrine regulators of prolactin secretion from the pituitary gland, also release GABA within the hypothalamic arcuate nucleus. As these neurons express prolactin receptors (Prlr)
Autor:
Tarcília Aparecida Silva, Soraia Macari, L. Ajay Sharma, David R. Grattan, Amanda Wyatt, George J. Dias, Gustavo Pompermaier Garlet, Penelope J. Knowles, Raphael E. Szawka
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Estrogen deficiency results in disruption of maxillary alveolar bone microarchitecture. Most of the actions of estrogen in long bones occur via estrogen receptor α (ERα). However, the function of ERα in the maxillary bone has not been defined. We
Autor:
Amanda Wyatt, Ryan E. Herbison, Sharon R Ladyman, William A. Banks, Nadine Binart, Rosemary S E Brown, David R. Grattan, Penelope J. Knowles
Publikováno v:
The FASEB Journal. 30:1002-1010
The anterior pituitary hormone prolactin exerts important physiologic actions in the brain. However, the mechanism by which prolactin crosses the blood-brain barrier and enters the brain is not completely understood. On the basis of high expression o
Autor:
Z. Khant Aung, Sharon R Ladyman, Rosemary S E Brown, Hollian R Phillipps, David R. Grattan, M. A. MacLeod, Penelope J. Knowles
Publikováno v:
Journal of neuroendocrinology. 29(10)
Among its many functions, prolactin has been implicated in energy homeostasis, particularly during pregnancy and lactation. The arcuate nucleus is a key site in the regulation of energy balance. The present study aimed to examine whether arcuate nucl
Publikováno v:
Journal of Neuroendocrinology. 23:224-231
The synthesis and secretion of catecholamines by the adrenal medulla is of major importance in the stress response. Tyrosine hydroxylase, the rate-limiting enzyme for catecholamine biosynthesis, has been extensively studied in adrenal medullary chrom
Publikováno v:
Neuroscience letters. 445(1)
Isolated adrenal medullary chromaffin cells maintained in culture have been widely used to study neurosecretory events. Many of these studies have been conducted using cells obtained from the bovine adrenal. In this study we have cultured chromaffin