Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Penelope J. Hopkins"'
Autor:
Sam Kassegne, Anita H. Forster, Marcus Tirado, Joon Mo Yang, Howard R. Reese, Penelope J. Hopkins, Ying Huang
Publikováno v:
Biomedical Microdevices. 5:217-225
Separation of simulants of biological warfare agents from blood using dielectrophoresis (DEP) was demonstrated in a miniaturized DEP device. The device was fabricated by laminating five different layers (all 40 mm×40 mm) including a polycarbonate su
Publikováno v:
European Journal of Human Genetics. 10:82-85
Tumour necrosis factor (TNF) alpha affects immune response and airway inflammation, which are characteristics of asthma. Genetic factors may impact TNFalpha levels, and several polymorphisms in the TNF gene cluster on chromosome 6p21 have been associ
Autor:
Dan Mercola, Jason J. Scalise, Robert E. Sobol, Ruth A. Gjerset, Penelope J. Hopkins, Heli Collins, Sally T. Turla
Publikováno v:
Molecular Carcinogenesis. 14:275-285
It is known that transfer of the wild-type p53 gene into p53-negative cells from transgenic mice increases their sensitivity to drug and radiation-induced apoptosis. However, unlike many human tumors, these transgenic cells do not express mutant p53,
Autor:
Nils Bergenhem, Richard E. Tashian, Penelope J. Hopkins, Patrick J. Venta, David Hewett-Emmett
Publikováno v:
Gene. 152:265-269
The structure of the gene encoding carbonic anhydrase I (CA I) was determined for the pigtail macaque Macaca nemestrina. When the deduced amino-acid sequence was compared with those of five other primates, four non-primate mammals and a turtle, seven
Publikováno v:
Clinics in Laboratory Medicine. 12:277-304
Chronic granulomatous disease (CGD) is caused by the failure of phagocytes to produce microbicidal derivatives of molecular oxygen, such as hydrogen peroxide. It is one of the best characterized of the phagocyte disorders and represents an important
Publikováno v:
Biochemical Genetics. 30:279-287
Autor:
Roy B. Jones, Penelope J. Hopkins, Jeffrey R. Marks, Susan Spruill, Gloria Broadwater, Jeff Hall, William P. Petros, O. Michael Colvin, James J. Vredenburgh, William P. Peters
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 23(25)
Purpose To evaluate associations between patient survival, pharmacokinetics, and drug metabolism–related genetic polymorphisms in patients receiving a combination chemotherapy regimen for breast cancer. Patients and Methods A genotype association s
Autor:
John T. Curnutte, David T. Barrett, Shixing Zhan, Penelope J. Hopkins, Joachim Roesler, Agnes Görlach, Barbara L. Christensen, Stephen J. Chanock, Pauline Lee
Publikováno v:
Blood cells, moleculesdiseases. 26(1)
The cytosolic factor p47-phox, encoded by the NCF1 gene, is an essential component of the phagocyte NADPH-oxidase system. Upon activation of this multicomponent system, p47-phox translocates to the membrane and participates in the electron transfer f
Autor:
John T. Curnutte, Penelope J. Hopkins, Mary C. Dinauer, Deborah Noack, Ryoko Kuruto, Peter E. Newburger, Julie Rae
SummaryChronic granulomatous disease (CGD) is a hereditary disorder of host defense due to absent or decreased activity of phagocyte NADPH oxidase. The X-linked form of the disease derives from defects in the CYBB gene, which encodes the 91-kD glycop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9149f5340fd8fcdb41526e806c057077
https://europepmc.org/articles/PMC1377153/
https://europepmc.org/articles/PMC1377153/
Autor:
Penelope J. Hopkins, Mary Kelly, Gail Shields, Timothy J. Crow, Robin Sherrington, J. Loftus, Antonio Vita, Angela B. Smith, Lon R. Cardon, Sarah H. Shaw, Lynn E. DeLisi, Marc De Hert, S. H. Laval
Publikováno v:
Università degli Studi di Brescia-IRIS
We completed a systematic genome-wide search for evidence of loci linked to schizophrenia using a collection of 70 pedigrees containing multiple affected individuals according to three phenotype classifications: schizophrenia only (48 pedigrees; 70 s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdac49547d6af5478187719c64caa999
http://hdl.handle.net/11379/6464
http://hdl.handle.net/11379/6464