Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Penelope J Boyd"'
Autor:
Kathryn Richardson, George M Savva, Penelope J Boyd, Clare Aldus, Ian Maidment, Eduwin Pakpahan, Yoon K Loke, Antony Arthur, Nicholas Steel, Clive Ballard, Robert Howard, Chris Fox
Publikováno v:
Health Technology Assessment, Vol 25, Iss 1 (2021)
Background: Sleep disturbance affects around 60% of people living with dementia and can negatively affect their quality of life and that of their carers. Hypnotic Z-drugs (zolpidem, zopiclone and zaleplon) are commonly used to treat insomnia, but the
Externí odkaz:
https://doaj.org/article/8ecbe4c035594e90a908b91c6dd530f1
Autor:
Penelope J Boyd, Wen-Yo Tu, Hannah K Shorrock, Ewout J N Groen, Roderick N Carter, Rachael A Powis, Sophie R Thomson, Derek Thomson, Laura C Graham, Anna A L Motyl, Thomas M Wishart, J Robin Highley, Nicholas M Morton, Thomas Becker, Catherina G Becker, Paul R Heath, Thomas H Gillingwater
Publikováno v:
PLoS Genetics, Vol 13, Iss 4, p e1006744 (2017)
Degeneration and loss of lower motor neurons is the major pathological hallmark of spinal muscular atrophy (SMA), resulting from low levels of ubiquitously-expressed survival motor neuron (SMN) protein. One remarkable, yet unresolved, feature of SMA
Externí odkaz:
https://doaj.org/article/6a1994812232441a91ce50a3acc16685
Publikováno v:
Age and Ageing. 48:273-277
Background: older people with frailty are particularly high users of healthcare services, however a lack of standardised recording of frailty in different healthcare electronic datasets has limited investigations into healthcare service usage and dem
Autor:
Eduwin Pakpahan, Yoon K. Loke, Clive Ballard, Antony Arthur, Chris Fox, Kathryn Richardson, Robert Howard, George M. Savva, Ian Maidment, Clare F Aldus, Penelope J Boyd, Nicholas Steel
Publikováno v:
Health Technology Assessment, Vol 25, Iss 1 (2021)
Health Technol Assess
Health Technol Assess
Background Sleep disturbance affects around 60% of people living with dementia and can negatively affect their quality of life and that of their carers. Hypnotic Z-drugs (zolpidem, zopiclone and zaleplon) are commonly used to treat insomnia, but thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a381e8be9b2a9cfdd650a4d7959190d
https://ueaeprints.uea.ac.uk/id/eprint/78122/
https://ueaeprints.uea.ac.uk/id/eprint/78122/
Autor:
Chris Fox, George M. Savva, Robert Howard, Nicholas Steel, Clive Ballard, Ian Maidment, Yoon K. Loke, Kathryn Richardson, Penelope J Boyd, Antony Arthur, Clare F Aldus
Publikováno v:
BMC Medicine
BackgroundSleep disturbance is common in dementia and often treated with Z-drugs (zopiclone, zaleplon, and zolpidem). While some observational studies suggest that Z-drugs are associated with adverse events such as falls and fracture risks in older p
Autor:
Kathryn Richardson, Antony Arthur, George M. Savva, Clive Ballard, Clare F Aldus, Yoon K Loke, Nicholas Steel, Chris Fox, Robert Howard, Penelope J Boyd, Eduwin Pakpahan, Ian Maidment
Publikováno v:
Alzheimer's & Dementia. 14
Autor:
Kathryn Richardson, Antony Arthur, George M. Savva, Chris Fox, Nicholas Steel, Ian Maidment, Clare F Aldus, Penelope J Boyd, Clive Ballard, Yoon K Loke, Robert Howard
Publikováno v:
Alzheimer's & Dementia. 14
Autor:
Hannah K, Shorrock, Dinja, van der Hoorn, Penelope J, Boyd, Maica, Llavero Hurtado, Douglas J, Lamont, Brunhilde, Wirth, James N, Sleigh, Giampietro, Schiavo, Thomas M, Wishart, Ewout J N, Groen, Thomas H, Gillingwater
Publikováno v:
Brain
Deafferentation of motor neurons as a result of defective sensory-motor connectivity in the spinal cord is an important early event in spinal muscular atrophy. Shorrock et al. report that this process is reversible in mice and results from disruption
Publikováno v:
Biology Open
Biology Open, Vol 4, Iss 10, Pp 1336-1343 (2015)
Biology Open, Vol 4, Iss 10, Pp 1336-1343 (2015)
DISRUPTED-IN-SCHIZOPHRENIA (DISC1) has been one of the most intensively studied genetic risk factors for mental illness since it was discovered through positional mapping of a translocation breakpoint in a large Scottish family where a balanced chrom
The neuromuscular junction (NMJ) is a specialized synapse, forming the primary connection between a lower motor neuron and a skeletal muscle fiber. Maintaining robust function of the NMJ is critical for healthy muscular contraction and movement, with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90874528b8fd18ff5fdf9c4a478eec8d
https://doi.org/10.1016/b978-0-12-803685-3.00008-2
https://doi.org/10.1016/b978-0-12-803685-3.00008-2