Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Penelope A. Jeggo"'
Autor:
Martin D. Burkhalter, Tom Stiff, Lars D. Maerz, Teresa Casar Tena, Heike Wiese, Julian Gerhards, Steffen A. Sailer, Linh Anna Trúc Vu, Max Duong Phu, Cornelia Donow, Marius Alupei, Sebastian Iben, Marco Groth, Sebastian Wiese, Joseph A. Church, Penelope A. Jeggo, Melanie Philipp
Publikováno v:
Cell Death and Disease, Vol 15, Iss 9, Pp 1-14 (2024)
Abstract The WD repeat-containing protein 4 (WDR4) has repeatedly been associated with primary microcephaly, a condition of impaired brain and skull growth. Often, faulty centrosomes cause microcephaly, yet aberrant cilia may also be involved. Here,
Externí odkaz:
https://doaj.org/article/c7c8e616bb0a44d686f248d5e16d846c
Autor:
Robert A. Baldock, Matthew Day, Oliver J. Wilkinson, Ross Cloney, Penelope A. Jeggo, Antony W. Oliver, Felicity Z. Watts, Laurence H. Pearl
Publikováno v:
Cell Reports, Vol 13, Iss 10, Pp 2081-2089 (2015)
53BP1 plays multiple roles in mammalian DNA damage repair, mediating pathway choice and facilitating DNA double-strand break repair in heterochromatin. Although it possesses a C-terminal BRCT2 domain, commonly involved in phospho-peptide binding in o
Externí odkaz:
https://doaj.org/article/c06c3687bc4d494f9663a7453ab3cb8b
Supplementary Figure Legends PDF file - 101K, Legends for Supplementary Figures S1-5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02dd6f0f91eaa95d50b8a5880a66a925
https://doi.org/10.1158/1541-7786.22516992
https://doi.org/10.1158/1541-7786.22516992
Publikováno v:
DNA Repair. 113:103304
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9798ad78421a78791ee8fb18021efdf4
https://doi.org/10.1016/j.dnarep.2022.103304
https://doi.org/10.1016/j.dnarep.2022.103304
Autor:
Penelope A. Jeggo, Thomas M. Rünger, Bernd Epe, Martin Poot, Martin Leverkus, Doris Hellfritsch, Markus Kotas
Publikováno v:
Tumor Biology. 24:100-108
Chromosomal instability plays a pivotal role in multistep carcinogenesis by facilitating the acquisition of the multiple genetic alterations necessary for malignant transformation. In order to study the role of abnormal DNA repair in malignant melano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66635213cba08b005d24831c1ae31051
https://doi.org/10.1159/000071083
https://doi.org/10.1159/000071083
Autor:
Aaron A, Goodarzi, Penelope A, Jeggo
Publikováno v:
Advances in genetics. 82
A DNA double-strand break (DSB) has long been recognized as a severe cellular lesion, potentially representing an initiating event for carcinogenesis or cell death. The evolution of DSB repair pathways as well as additional processes, such as cell cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7c1adfdd6e32d7e822086b4a11b310ec
https://pubmed.ncbi.nlm.nih.gov/23721719
https://pubmed.ncbi.nlm.nih.gov/23721719
Publikováno v:
The FASEB Journal. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8db907c7d459424eb4fc96cd70b5e365
https://doi.org/10.1096/fasebj.24.1_supplement.411.1
https://doi.org/10.1096/fasebj.24.1_supplement.411.1