Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Penelope A Boyden"'
Publikováno v:
Arrhythmia & Electrophysiology Review, Vol 10, Iss 3, Pp 190-197 (2021)
Externí odkaz:
https://doaj.org/article/6df29661eefb49a7a3de3a16a18c570a
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106830 (2014)
Because structural remodeling of several proteins, including ion channels, may underlie the abnormal action potentials of Purkinje cells (PCs) that survive in the 48 hr infarcted zone of the canine heart (IZPCs), we sought to determine the subcellula
Externí odkaz:
https://doaj.org/article/6c00919ca9974a5e83ae52ea27ef63f1
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78087 (2013)
Cardiac Na channel remodeling provides a critical substrate for generation of reentrant arrhythmias in border zones of the infarcted canine heart. Recent studies show that Nav1.5 assembly and function are linked to ankyrin-G, gap, and mechanical junc
Externí odkaz:
https://doaj.org/article/0a5405f05cf849acac5e999daa014736
Autor:
Matthew D Christensen, Wen Dun, Penelope A Boyden, Mark E Anderson, Peter J Mohler, Thomas J Hund
Publikováno v:
PLoS Computational Biology, Vol 5, Iss 12, p e1000583 (2009)
Calmodulin kinase II (CaMKII) mediates critical signaling pathways responsible for divergent functions in the heart including calcium cycling, hypertrophy and apoptosis. Dysfunction in the CaMKII signaling pathway occurs in heart disease and is assoc
Externí odkaz:
https://doaj.org/article/0262aead4d844d6b9cfe94d9bc14eefd
Publikováno v:
Arrhythmia & electrophysiology review, vol 10, iss 3
Arrhythmia & Electrophysiology Review
Arrhythmia & Electrophysiology Review, Vol 10, Iss 3, Pp 190-197 (2021)
Arrhythmia & Electrophysiology Review
Arrhythmia & Electrophysiology Review, Vol 10, Iss 3, Pp 190-197 (2021)
The His-Purkinje system is a network of bundles and fibres comprised of specialised cells that allow for coordinated, synchronous activation of the ventricles. Although the histology and physiology of the His-Purkinje system have been studied for mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa6bb80952680b80f5bc70fa725c1077
https://escholarship.org/uc/item/0g27b1c4
https://escholarship.org/uc/item/0g27b1c4
Publikováno v:
Heart rhythm, 16(7), 1121-1126. Elsevier
Much has been written about arrhythmias in structurally normal hearts. In this review, we focus on rapid ventricular arrhythmias that occur in hearts having a pathogenic genetic variant that has been found in families in which arrhythmias occur. We d
Publikováno v:
Prog Biophys Mol Biol
This article reviews work over the past three decades that is related to the contribution of the pacemaker current, If, to basal and autonomically regulated spontaneous rate in the sinoatrial node. It also addresses how the actions of the pacemaker c
Autor:
Donald M. Bers, Tamás Bányász, Penelope A. Boyden, Leighton T. Izu, Masahito Miura, Peter Kohl, Nipavan Chiamvimonvat, Natalia A. Trayanova, Ye Chen-Izu
Publikováno v:
The Journal of physiology, vol 598, iss 7
J Physiol
J Physiol
Cardiac excitation-contraction (E-C) coupling is influenced by (at least) three dynamic systems that couple and feedback to one another (Abstract Figure). Here we review the mechanical effects on cardiomyocytes that include mechano-electro-transducti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f41721d7c30e03e5f20d2de4616d8aa
https://escholarship.org/uc/item/2dj257vh
https://escholarship.org/uc/item/2dj257vh
Publikováno v:
Pacing and clinical electrophysiology : PACE, vol 41, iss 9
His-Purkinje-related ventricular arrhythmias are a subset of ventricular tachycardias that use the specialized cardiac conduction system. These arrhythmias can occur in various different forms of structural heart disease. Here, we review the basic sc
Autor:
Penelope A. Boyden
Publikováno v:
Journal of Interventional Cardiac Electrophysiology. 52:255-262
There has always been an appreciation of the role of Purkinje fibers in the fast conduction of the normal cardiac impulse. Here, we briefly update our knowledge of this important set of cardiac cells. We discuss the anatomy of a Purkinje fiber strand