Piezo1–Pannexin1 complex couples force detection to ATP secretion in cholangiocytes

Autor: Desplat, Angélique, Penalba, Virginie, Gros, Emeline, Parpaite, Thibaud, Coste, Bertrand, Delmas, Patrick

Publikováno v: Journal of General Physiology
Journal of General Physiology, 2021, 153 (12), ⟨10.1085/jgp.202112871⟩
Journal of General Physiology, Rockefeller University Press, 2021, 153 (12), ⟨10.1085/jgp.202112871⟩

International audience; Cholangiocytes actively contribute to the final composition of secreted bile. These cells are exposed to abnormal mechanical stimuli during obstructive cholestasis, which has a deep impact on their function. However, the effec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f93116e749e6d65a03bdd509ffd0db56
https://hal.science/hal-03420422/document

Maladaptive activation of Nav1.9 channels by nitric oxide causes triptan-induced medication overuse headache

Autor: Bonnet, Caroline, Hao, Jizhe, Osorio, Nancy, Donnet, Anne, Penalba, Virginie, Ruel, Jérôme, Delmas, Patrick

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications, 2019, 10 (1), ⟨10.1038/s41467-019-12197-3⟩
Nature Communications, Nature Publishing Group, 2019, 10 (1), ⟨10.1038/s41467-019-12197-3⟩

Medication-overuse headaches (MOH) occur with both over-the-counter and pain-relief medicines, including paracetamol, opioids and combination analgesics. The mechanisms that lead to MOH are still uncertain. Here, we show that abnormal activation of N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9246e4468d27f6eebf2f0afcfbc7cac3
https://doaj.org/article/13bb724449b94f508ae02468f5087389

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Author Correction: Maladaptive activation of Nav1.9 channels by nitric oxide causes triptan-induced medication overuse headache.

Autor: Bonnet, Caroline, Hao, Jizhe, Osorio, Nancy, Donnet, Anne, Penalba, Virginie, Ruel, Jérôme, Delmas, Patrick

Publikováno v: Nature Communications; 11/23/2021, Vol. 12 Issue 1, p1-1, 1p