Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Pen-Hsiu Grace Chao"'
Autor:
Ya-Hui Chi, Wan-Ping Wang, Ming-Chun Hung, Gunn-Guang Liou, Jing-Ya Wang, Pen-Hsiu Grace Chao
Publikováno v:
Epigenetics & Chromatin, Vol 15, Iss 1, Pp 1-17 (2022)
Abstract The cause of nuclear shape abnormalities which are often seen in pre-neoplastic and malignant tissues is not clear. In this study we report that deformation of the nucleus can be induced by TGFβ1 stimulation in several cell lines including
Externí odkaz:
https://doaj.org/article/179eb39224d3408090865197ecf1df5f
Autor:
Farid Alisafaei, Delaram Shakiba, Leanne E. Iannucci, Matthew D. Davidson, Kenneth M. Pryse, Pen-hsiu Grace Chao, Jason A. Burdick, Spencer P. Lake, Elliot L. Elson, Vivek B. Shenoy, Guy M. Genin
Mechanical factors such as stress in the extracellular environment are known to affect phenotypic commitment of cells. However, the stress fields experienced by cells in tissues are multiaxial, and the ways that cells integrate this multiaxial inform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e14667016dc8588aea829aecff111bc4
https://doi.org/10.1101/2022.03.13.484154
https://doi.org/10.1101/2022.03.13.484154
Publikováno v:
Acta biomaterialia. 152
Tissues and the embedded cells experience anisotropic deformations due to their functions and anatomical locations. The resident cells, such as tenocytes and muscle cells, are often restricted by their extracellular matrix and organize parallel to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf37aea59f99f6ef25c988b8283e7a26
https://pubmed.ncbi.nlm.nih.gov/36089236
https://pubmed.ncbi.nlm.nih.gov/36089236
Autor:
Ya-Hui Chi, Ming-Chun Hung, Pen-Hsiu Grace Chao, Gunn-Guang Liou, Jing-Ya Wang, Wan-Ping Wang
Publikováno v:
Epigenetics & Chromatin, Vol 15, Iss 1, Pp 1-17 (2022)
Epigenetics & Chromatin
Epigenetics & Chromatin
The cause of nuclear shape abnormalities which are often seen in pre-neoplastic and malignant tissues is not clear. In this study we report that deformation of the nucleus can be induced by TGFb1 stimulation in several cell lines including Huh7. In o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97c24b023136cd05266ddf98d39fff35
https://doi.org/10.21203/rs.3.rs-944682/v1
https://doi.org/10.21203/rs.3.rs-944682/v1
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 14
International Journal of Molecular Sciences, Vol 22, Iss 7725, p 7725 (2021)
Volume 22
Issue 14
International Journal of Molecular Sciences, Vol 22, Iss 7725, p 7725 (2021)
Reconstruction of the periodontal ligament (PDL) to fulfill functional requirement remains a challenge. This study sought to develop a biomimetic microfibrous system capable of withstanding the functional load to assist PDL regeneration. Collagen-bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3dccacbee1c2e23dacc973008ae3d41
Autor:
Robert L. Mauck, Tonia K. Tsinman, Harvey E. Smith, Edward D. Bonnevie, Dawn M. Elliott, Sarah E. Gullbrand, Beth G. Ashinsky, Pen-Hsiu Grace Chao
Publikováno v:
Nature biomedical engineering
In fibrous tissues, prestressed boundary constraints at bone interfaces instil residual strain throughout the tissue, even when unloaded. For example, internal swelling pressures in the central nucleus pulposus of the intervertebral disc generate pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f1e5e20dc71936b8ff86b3e80779df9
https://doi.org/10.1038/s41551-019-0458-4
https://doi.org/10.1038/s41551-019-0458-4
Autor:
Shih Ting Chen, Pin Chen Lin, Chih-Yu Wu, Hsien-Yeh Chen, Po Chun Chen, Po Kang Lin, Pen-Hsiu Grace Chao, Zhen Yu Guan
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 175:545-553
The field of implantable electronics relies on using silicon materials due to the merits of a well-established fabrication process and favorable properties; of particular interest is the surface modification of such materials. In the present study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2210db639be65370e7f97e8369828f8
https://doi.org/10.1016/j.colsurfb.2018.12.034
https://doi.org/10.1016/j.colsurfb.2018.12.034
Publikováno v:
Proceedings of the National Academy of Sciences. 114:8568-8573
Endogenous electric fields (EFs) are involved in developmental regulation and wound healing. Although the phenomenon is known for more than a century, it is not clear how cells perceive the external EF. Membrane proteins, responding to electrophoreti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18523dac627196f1e60dcf65a6dbe7e8
https://doi.org/10.1073/pnas.1702526114
https://doi.org/10.1073/pnas.1702526114
Autor:
Pen-Hsiu Grace Chao, Xiaoning Yuan, Johnathan Ng, Derya E. Arkonac, Yiyong Wei, Aranzazu Villasante, Gordana Vunjak-Novakovic
Publikováno v:
Biomaterials. 132:59-71
Interest in non-invasive injectable therapies has rapidly risen due to their excellent safety profile and ease of use in clinical settings. Injectable hydrogels can be derived from the extracellular matrix (ECM) of specific tissues to provide a biomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e911fd511baa4b08f2b5526643c571
https://doi.org/10.1016/j.biomaterials.2017.04.004
https://doi.org/10.1016/j.biomaterials.2017.04.004
Autor:
Tristan P. Driscoll, Spencer E. Szczesny, Hsiao Yun Tseng, Su Jin Heo, Robert L. Mauck, Pen-Hsiu Grace Chao, Pang Ching Liu
Publikováno v:
ACS Biomaterials Science & Engineering. 3:2869-2876
To fully recapitulate tissue microstructure and mechanics, fiber crimping must exist within biomaterials used for tendon/ligament engineering. Existing crimped nanofibrous scaffolds produced via electrospinning are dense materials that prevent cellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be2db67629e95073a83ff57e9284029a
https://doi.org/10.1021/acsbiomaterials.6b00646
https://doi.org/10.1021/acsbiomaterials.6b00646