Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Pemra Ozbek"'
Autor:
Hande Beklen, Sema Arslan, Gizem Gulfidan, Beste Turanli, Pemra Ozbek, Betul Karademir Yilmaz, Kazim Yalcin Arga
Publikováno v:
Frontiers in Bioinformatics, Vol 1 (2021)
There is a critical requirement for alternative strategies to provide the better treatment in colorectal cancer (CRC). Hence, our goal was to propose novel biomarkers as well as drug candidates for its treatment through differential interactome based
Externí odkaz:
https://doaj.org/article/2999ef6b66e3445bafd3e487c38a5771
Autor:
Onur Serçinoğlu, Pemra Ozbek
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232849 (2020)
Class I Major Histocompatibility Complex (MHC) binds short antigenic peptides with the help of Peptide Loading Complex (PLC), and presents them to T-cell Receptors (TCRs) of cytotoxic T-cells and Killer-cell Immunglobulin-like Receptors (KIRs) of Nat
Externí odkaz:
https://doaj.org/article/3e5fbf81ef5c49989e0296c9a20f57fe
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 10, p e1004461 (2015)
Protein-protein interfaces have been evolutionarily-designed to enable transduction between the interacting proteins. Thus, we hypothesize that analysis of the dynamics of the complex can reveal details about the nature of the interaction, and in par
Externí odkaz:
https://doaj.org/article/3ff12170bc824125bfce94fcbdcfa0d3
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74320 (2013)
It is of significant interest to understand how proteins interact, which holds the key phenomenon in biological functions. Using dynamic fluctuations in high frequency modes, we show that the Gaussian Network Model (GNM) predicts hot spot residues wi
Externí odkaz:
https://doaj.org/article/822bad0794a94d3fb9c38dab3db23b0b
Akademický článek
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Publikováno v:
Pathog Glob Health
The production of β-lactamases is a prevalent mechanism that poses serious pressure on the control of bacterial resistance. Furthermore, the unavoidable and alarming increase in the transmission of bacteria producing extended-spectrum β-lactamases
Autor:
Shabnam Mohammadi, Halil İbrahim Özdemir, Pemra Ozbek, Fidan Sumbul, Josefin Stiller, Yuan Deng, Andrew J. Crawford, Hannah M. Rowland, Jay F. Storz, Peter Andolfatto, Susanne Dobler
The recurrent evolution of resistance to cardiotonic steroids (CTS) across diverse animals most frequently involves convergent amino-acid substitutions to the H1-H2 extracellular loop of Na+,K+-ATPase (NKA). Previous work established that hystricogna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbb654bea4c80236d3bad60fb09a7ef0
https://doi.org/10.1101/2022.09.01.506169
https://doi.org/10.1101/2022.09.01.506169
© 2022 Elsevier Inc.The connection of Epstein Barr virus (EBV) with diseases such as Burkitt Lymphoma, Hodgkin disease, multiple sclerosis, systemic lupus erythematosus and various B-cell lymphomas made EBV glycoproteins one of the most popular vacc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e28c7251dd98264ac1fe6b0860de17e6
https://hdl.handle.net/11424/289536
https://hdl.handle.net/11424/289536
Publikováno v:
Journal of Chemical Information and Modeling. 61:2444-2453
Antigen presentation by major histocompatibility complex (MHC) proteins to T-cell receptors (TCRs) plays a crucial role in triggering the adaptive immune response. Most of our knowledge on TCR-peptide-loaded major histocompatibility complex (pMHC) in
Autor:
Metin Yazar, Pemra Ozbek
© 2022 Elsevier LtdSingle nucleotide variants (SNVs) are single base substitutions that could influence many biological functions in the cell including gene expression, protein folding, and protein-protein interactions among many others. Thus, predi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ed2998f4cda87cefd527639206687b
https://hdl.handle.net/11424/289558
https://hdl.handle.net/11424/289558