Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Pema Maretich"'
Autor:
Min Yang, Jing Ge, Yu-Lian Liu, Huan-Yu Wang, Zhi-Han Wang, Dan-Pei Li, Rui He, Yu-Yu Xie, Hong-Yan Deng, Xue-Min Peng, Wen-She Wang, Jia-Dai Liu, Zeng-Zhe Zhu, Xue-Feng Yu, Pema Maretich, Shingo Kajimura, Ru-Ping Pan, Yong Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Beige fat activation involves a fuel switch to fatty acid oxidation following chronic cold adaptation. Mitochondrial acyl-CoA synthetase long-chain family member 1 (ACSL1) localizes in the mitochondria and plays a key role in fatty acid oxid
Externí odkaz:
https://doaj.org/article/35f6336cc18f4ad4a0ac9089445e2439
Autor:
John H Day, Catherine M Della Santina, Pema Maretich, Alexander L Auld, Kirsten K Schnieder, Tay Shin, Edward S Boyden, Laurie A Boyer
Publikováno v:
eLife, Vol 13 (2024)
Expansion microscopy (ExM) enables nanoscale imaging using a standard confocal microscope through the physical, isotropic expansion of fixed immunolabeled specimens. ExM is widely employed to image proteins, nucleic acids, and lipid membranes in sing
Externí odkaz:
https://doaj.org/article/7347856438fd4b8699c28a0773fb92c0
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Brown and beige adipose tissues play a large role in non-shivering thermogenesis (NST) in mammals, and subsequently have been studied for decades as potential therapeutic targets to treat obesity and its related metabolic diseases. However, the mecha
Externí odkaz:
https://doaj.org/article/683fc6de505f4d3fb1e4a67de7342649
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Brown fat and beige fat are known as thermogenic fat due to their contribution to non-shivering thermogenesis in mammals following cold stimulation. Beige fat is unique due to its origin and its development in white fat. Subsequently, both brown fat
Externí odkaz:
https://doaj.org/article/9dd9370777524e089dde47bf8397c19d
Autor:
Yong Chen, Min Yang, Zengzhe Zhu, Rui He, Danpei Li, Zhihan Wang, Yuyu Xie, Huanyu Wang, Hongyan Deng, Jiadai Liu, Xuefeng Yu, Ruping Pan, Pema Maretich, Shingo Kajimura
Obesity and its related metabolic disorders are caused by an imbalance between homeostatic energy consumption and expenditure. Brown and beige adipose tissues have been shown to be protective against these diseases due to their critical roles in non-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f8dbab212a46e200859d3eb4774a2ff
https://doi.org/10.21203/rs.3.rs-2667036/v1
https://doi.org/10.21203/rs.3.rs-2667036/v1
Autor:
Vaishnavi V. Phadnis, Emily L. Ricq, Bryan Ferguson, Laurie A. Boyer, John K. Eaton, Yilong Zou, Emily T. Graham, Sateja Paradkar, Stuart L. Schreiber, Pema Maretich, Heather R. Keys, Paul A. Clemons, Whitney S. Henry, Ferenc Reinhardt, Natalie Boehnke, Joshua Fairman, Amy Deik, Vlado Dančík, Robert A. Weinberg, Clary B. Clish, Paula T. Hammond, Wenyu Wang
Publikováno v:
Nature. 585:603-608
Ferroptosis—an iron-dependent, non-apoptotic cell death process—is involved in various degenerative diseases and represents a targetable susceptibility in certain cancers1. The ferroptosis-susceptible cell state can either pre-exist in cells that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27559b6580ec0119a3287ef6713a813e
https://doi.org/10.1038/s41586-020-2732-8
https://doi.org/10.1038/s41586-020-2732-8
Autor:
Pema Maretich, Jacqueline A. Lees, Marguerite Blair, Joon Ho Kang, Hannah R. Hagen, Jette Lengefeld, Chia-Wei Cheng, Adam Antebi, Joachim D. Steiner, Sean J. Morrison, Angelika Amon, Teemu P. Miettinen, Scott R. Manalis, Emily Sullivan, Melanie R. McReynolds, Laurie A. Boyer, Christina Roberts, Ömer H. Yilmaz, Kyra Majors
Publikováno v:
Science Advances
Sci Adv
Sci Adv
Description
Small cell size preserves the function of hematopoietic stem cells (HSCs); HSC enlargement during aging causes their dysfunction.
Stem cells are remarkably small. Whether small size is important for stem cell function is unknown
Small cell size preserves the function of hematopoietic stem cells (HSCs); HSC enlargement during aging causes their dysfunction.
Stem cells are remarkably small. Whether small size is important for stem cell function is unknown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cef0359cfcab8c62dbdd1603e75e9093
https://pubmed.ncbi.nlm.nih.gov/34824454
https://pubmed.ncbi.nlm.nih.gov/34824454
Autor:
Joon Ho Kang, Marguerite Blair, Pema Maretich, Chia-Wei Cheng, Adam Antebi, Sean J. Morrison, Joachim D. Steiner, Laurie A. Boyer, Christina Roberts, Angelika Amon, Jacqueline A. Lees, Jette Lengefeld, Kyra Majors, Melanie R. McReynolds, Scott R. Manalis, Hannah R. Hagen, Teemu P. Miettinen, Ömer H. Yilmaz, Emily Sullivan
Stem cells are remarkably small in size. Whether small size is important for stem cell function is unknown. We find that murine hematopoietic stem cells (HSCs) enlarge under conditions known to decrease stem cell function. This decreased fitness of l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24a7dfd1fa21c9d83fbc6da6eb5f60d1
https://doi.org/10.1101/2020.10.27.355388
https://doi.org/10.1101/2020.10.27.355388
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Brown and beige adipose tissues play a large role in non-shivering thermogenesis (NST) in mammals, and subsequently have been studied for decades as potential therapeutic targets to treat obesity and its related metabolic diseases. However, the mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a03e1b89ff6248eb0055fcbb5faeeb7
https://www.frontiersin.org/article/10.3389/fendo.2020.00633/full
https://www.frontiersin.org/article/10.3389/fendo.2020.00633/full
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Frontiers in Endocrinology
Frontiers in Endocrinology
Brown fat and beige fat are known as thermogenic fat due to their contribution to non-shivering thermogenesis in mammals following cold stimulation. Beige fat is unique due to its origin and its development in white fat. Subsequently, both brown fat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d198eed5e5d58c3b4d931b1c0015f3f
https://pubmed.ncbi.nlm.nih.gov/32351446
https://pubmed.ncbi.nlm.nih.gov/32351446