Low prevalence of archived integrase strand transfer inhibitors resistance associated mutations in Botswana before the roll out of dolutegravir based first line antiretroviral therapy.

Autor: Maruapula D; Botswana Harvard Health Partnership, Gaborone, Botswana., Ditshwanelo D; Botswana Harvard Health Partnership, Gaborone, Botswana., Pema MN; Botswana Harvard Health Partnership, Gaborone, Botswana., Bareng OT; Botswana Harvard Health Partnership, Gaborone, Botswana.; Faculty of Health Sciences, Medical Laboratory Sciences, University of Botswana, Gaborone, Botswana., Choga WT; Botswana Harvard Health Partnership, Gaborone, Botswana.; Faculty of Health Sciences, Medical Laboratory Sciences, University of Botswana, Gaborone, Botswana., Moraka NO; Botswana Harvard Health Partnership, Gaborone, Botswana.; Faculty of Health Sciences, Medical Laboratory Sciences, University of Botswana, Gaborone, Botswana., Mokgethi PT; Botswana Harvard Health Partnership, Gaborone, Botswana.; Department of Biological Sciences, University of Botswana, Gaborone, Botswana., Seatla KK; Botswana Harvard Health Partnership, Gaborone, Botswana., Koofhethile CK; Botswana Harvard Health Partnership, Gaborone, Botswana.; Department of Immunology and Infectious Diseases, Harvard University T.H Chan School of Public Health, Boston, MA, United States., Zuze BJ; Botswana Harvard Health Partnership, Gaborone, Botswana., Gaolathe T; Botswana Harvard Health Partnership, Gaborone, Botswana., Pretorius-Holme M; Department of Immunology and Infectious Diseases, Harvard University T.H Chan School of Public Health, Boston, MA, United States., Lebani K; Department of Biological Sciences and Biotechnology, Botswana International University of Science and Technology, Palapye, Botswana., Makhema J; Botswana Harvard Health Partnership, Gaborone, Botswana.; Department of Immunology and Infectious Diseases, Harvard University T.H Chan School of Public Health, Boston, MA, United States., Novitsky V; Botswana Harvard Health Partnership, Gaborone, Botswana., Shapiro R; Botswana Harvard Health Partnership, Gaborone, Botswana.; Department of Immunology and Infectious Diseases, Harvard University T.H Chan School of Public Health, Boston, MA, United States., Lockman S; Botswana Harvard Health Partnership, Gaborone, Botswana.; Department of Immunology and Infectious Diseases, Harvard University T.H Chan School of Public Health, Boston, MA, United States.; Division of Infectious Disease, Brigham and Women's Hospital, Boston, MA, United States., Moyo S; Botswana Harvard Health Partnership, Gaborone, Botswana.; Department of Immunology and Infectious Diseases, Harvard University T.H Chan School of Public Health, Boston, MA, United States.; School of Health Systems and Public Health, Faculty of Sciences, University of Pretoria, Pretoria, South Africa., Gaseitsiwe S; Botswana Harvard Health Partnership, Gaborone, Botswana.; Department of Immunology and Infectious Diseases, Harvard University T.H Chan School of Public Health, Boston, MA, United States.

Publikováno v: Frontiers in microbiology [Front Microbiol] 2024 Oct 24; Vol. 15, pp. 1482348. Date of Electronic Publication: 2024 Oct 24 (Print Publication: 2024).

Predicted broadly neutralizing antibody (bnAb) resistance and associated envelope characteristics of adults with HIV-1 seroconversion in Botswana.

Autor: Moraka NO; Botswana Harvard AIDS Institute Partnership., Choga WT; Botswana Harvard AIDS Institute Partnership., Pema MN; Botswana Harvard AIDS Institute Partnership., Chawawa MK; Botswana Harvard AIDS Institute Partnership., Gobe I; University of Botswana., Mokomane M; University of Botswana., Bareng OT; Botswana Harvard AIDS Institute Partnership., Bhebhe L; Botswana Harvard AIDS Institute Partnership., Kelentse N; Botswana Harvard AIDS Institute Partnership., Mulenga G; Botswana Harvard AIDS Institute Partnership., Pretorius-Holme M; Harvard University., Mohammed T; Botswana Harvard AIDS Institute Partnership., Koofhethile CK; Botswana Harvard AIDS Institute Partnership., Makhema JM; Botswana Harvard AIDS Institute Partnership., Shapiro R; Harvard University., Lockman S; Harvard University., Moyo S; Botswana Harvard AIDS Institute Partnership., Gaseitsiwe S; Botswana Harvard AIDS Institute Partnership.

Publikováno v: Research square [Res Sq] 2023 Aug 29. Date of Electronic Publication: 2023 Aug 29.