Výsledky vyhledávání - "Pelvic peritoneum"

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Walthard Cell Nests/Transitional Cell Metaplasia in Distal Fallopian Tubes and Pelvic Peritoneum Derived From Reserve Cells.

Autor: Jo U; Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine., Sung CO; Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine., Kim KR; Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine.; Department of Pathology, Seegene Medical Foundation, Seoul, Korea.

Publikováno v: International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists [Int J Gynecol Pathol] 2024 Dec 03. Date of Electronic Publication: 2024 Dec 03.

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Cross-Tissue Regulatory Network Analyses Reveal Novel Susceptibility Genes and Potential Mechanisms for Endometriosis Endometriosis (EMT) is a common gynecological disease with a strong genetic component, while its precise etiology remains elusive. This study aims to integrate transcriptome-wide association study (TWAS), Mendelian randomization (MR), and bioinformatics analyses to reveal novel putatively causal genes and potential mechanisms. We obtained summary-level data of the Genotype-Tissue Expression Project (GTEx), v8 expression quantitative loci (eQTL) data, and the genome-wide association study (GWAS) data of EMT and its subtypes from the R11 release results of the FinnGen consortium for analysis. GWAS data of modifiable risk factors were collected from IEU Open GWAS. Cross-tissue TWAS analyses were performed using the unified test for molecular signature (UTMOST), while functional summary-based imputation (FUSION) was employed for single-tissue TWAS analyses. Furthermore, we also conducted multi-marker analysis of genomic annotation (MAGMA) analyses to validate the significant associations. Subsequent Mendelian randomization (MR) and colocalization analysis elucidated the causal associations between the identified genes across various tissues and EMT. To further delve into mechanisms, two-sample network MR analyses were conducted. At last, bioinformatics analyses were employed to enhance our understanding of the functional implications and expression patterns of these identified genes. For EMT, 22 significant gene signals were identified by UTMOST, 615 by FUSION, and 354 by MAGMA. Ultimately, six genes, including CISD2, EFRB, GREB1, IMMT, SULT1E1, and UBE2D3, were identified as candidate susceptibility genes for EMT. Through similar procedures, we identified GREB1, IL1A, and SULT1E1 for EMT of the ovary, and we identified GREB1 for EMT of the pelvic peritoneum, EMT of rectovaginal septum and vagina, and deep EMT. In MR analyses, the expression of IMMT in 2

Autor: Zou, Mingrui^1,2,3,4,5 (AUTHOR) 2110301145@stu.pku.edu.cn, Lin, Mingmei^1,2,3,4 (AUTHOR) linmingmei2023@163.com, Hu, Kai-Lun^1,2,3,4 (AUTHOR) hukailun@bjmu.edu.cn, Li, Rong^1,2,3,4 (AUTHOR) hukailun@bjmu.edu.cn

Publikováno v: Biology (2079-7737). Nov2024, Vol. 13 Issue 11, p871. 18p.

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Surgical efficacy and quality of wide resection of the pelvic peritoneum in patients with epithelial ovarian cancer

Autor: Nishimura, Akiho, Motohara, Takeshi, Morinaga, Jun, Iwagoi, Yutaka, Yamamoto, Mayuko, Yamaguchi, Munekage, Miyahara, Yo, Tashiro, Hironori, Katabuchi, Hidetaka

Publikováno v: In Surgical Oncology June 2023 48

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Laparoscopic right hemicolectomy with aortocaval lymphadenectomy, and pelvic peritoneum partial resection for ascending colon cancer

Autor: Hannah Kim, An Na Seo, Soo Yeun Park

Publikováno v: Annals of Coloproctology, Vol 39, Iss 3, Pp 283-286 (2023)

The aim of this video is to present the procedural details of laparoscopic right hemicolectomy with aortocaval (infrarenal aortic bifurcation) lymphadenectomy, partial resection of the pelvic peritoneum (peritoneal carcinomatosis index, 3), and hyper

Externí odkaz: https://doaj.org/article/9d12d27c467f49c599a2e795cdab816c

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Spillage and displacement of indocyanine green-stained tissues from uterine cervix to pelvic peritoneum: A proof of concept study for colpotomy approach in minimally invasive surgery

Autor: Tae-Wook Kong, Jimin Lee, Sun Hyung Yum, Jeeyeon Kim, Joo-Hyuk Son, Suk-Joon Chang, Hee-Sug Ryu

Publikováno v: Taiwanese Journal of Obstetrics & Gynecology, Vol 62, Iss 1, Pp 119-122 (2023)

Objective: To analyze peritoneal spillage and displacement of indocyanine green (ICG)-stained tissues from uterine cervix to pelvis during intracorporeal/vaginal colpotomy in laparoscopic-assisted hysterectomy. Materials and methods: Eleven patients

Externí odkaz: https://doaj.org/article/123ad0f5d43a40d9af4b1d14ce4b0082

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