Zobrazeno 1 - 10
of 304
pro vyhledávání: '"Pellet Dosage Form"'
Autor:
Mr. Madhu, B.K., Dr. Anu Kaushik
Broadened discharge drug drugs have as of late arisen as an exceptionally down to earth device in clinical work on, giving patients different genuine and saw benefits. Since it is more straightforward to regulate and brings about higher patient consi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b84528e5fbdd79eac3a15dc0a4ce56ff
Autor:
Sunil Kumar Battu, Joseph T. Morott, Michael A. Repka, Majumdar Soumyajit, Sindhuri Maddineni
Publikováno v:
Journal of Pharmacy and Pharmacology. 66:309-322
ObjectiveThe objective of this study was to develop techniques for an abuse-deterrent (AD) platform utilizing the hot-melt extrusion (HME) process.MethodsFormulation optimization was accomplished by utilizing Box–Behnken design of experiments to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::555f109b32ae5bf48fbe94820eea374f
https://doi.org/10.1111/jphp.12129
https://doi.org/10.1111/jphp.12129
Publikováno v:
Archives of Pharmacal Research. 34:1135-1142
In the present study, an extended release pellet dosage form of ketoprofen was prepared using powder layering technique. A combination of ethyl cellulose (45 cps) and shellac polymers was used as a binder (12% w/w polymer) during drug layering and an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d311b3c036e1d3b2eb5bae2bd800656
https://doi.org/10.1007/s12272-011-0711-1
https://doi.org/10.1007/s12272-011-0711-1
Autor:
Dima Ghanam, Peter Kleinebudde
Publikováno v:
International Journal of Pharmaceutics. 409:9-18
κ-Carrageenan is a novel pelletisation aid with high formulation robustness and quick disintegration leading to fast drug release unlike the matrix-like release from non-disintegrating microcrystalline cellulose pellets. Compression of pellets into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eed119bb675be3bede59123a82b841ea
https://doi.org/10.1016/j.ijpharm.2011.02.016
https://doi.org/10.1016/j.ijpharm.2011.02.016
Autor:
Yassin Farag, Claudia S. Leopold
Publikováno v:
European Journal of Pharmaceutical Sciences. 42:400-405
Shellac is an important coating material for food products. Since the introduction of aqueous ammoniacal solutions it also regained importance for pharmaceutical applications. Because of the comparatively high dissolution pH of this material, further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf38940b19907ab326b723c8a8cda4a0
https://doi.org/10.1016/j.ejps.2011.01.006
https://doi.org/10.1016/j.ejps.2011.01.006
Publikováno v:
Combinatorial Chemistry & High Throughput Screening. 14:138-145
Powder layering technique was evaluated using laboratory scale centrifugal granulator instrument to prepare extended release pellet dosage form of ketoprofen. Ethyl cellulose and shellac polymers were used for drug layering and extended release coati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6f8af974b1010b509c2202a9502d10
https://doi.org/10.2174/138620711794474042
https://doi.org/10.2174/138620711794474042
Autor:
Hea-Eun Lee, Da-Young Seo, Myung Yung Jeong, Guang J. Choi, In-Chun Wang, Min-Jeong Lee, Woo-Sik Kim
Publikováno v:
International Journal of Pharmaceutics. 403:66-72
Along with the risk-based approach, process analytical technology (PAT) has emerged as one of the key elements to fully implement QbD (quality-by-design). Near-infrared (NIR) spectroscopy has been extensively applied as an in-line/on-line analytical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb33d7d7a1cac8520171cfc7925745d
https://doi.org/10.1016/j.ijpharm.2010.10.022
https://doi.org/10.1016/j.ijpharm.2010.10.022
Autor:
Narubodee Phadoongsombut, Saipin Setthacheewakul, Sirima Mahattanadul, Wiwat Pichayakorn, Ruedeekorn Wiwattanapatapee
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 76:475-485
This study describes the development and characterization of self-microemulsifying drug delivery systems (SMEDDS) in liquid and pellet forms that result in improved solubility, dissolution, and in vivo oral absorption of the poorly water-soluble comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5342385ac5b8d1a25dd4919252d36f
https://doi.org/10.1016/j.ejpb.2010.07.011
https://doi.org/10.1016/j.ejpb.2010.07.011
Publikováno v:
International Journal of Pharmaceutics. 400:138-144
The major aim of this study was to prepare isosorbide-5-mononitrate (5-ISMN) sustained-release pellets and evaluate their stability. The pellets were prepared by extrusion/spheronization, and then the core pellets were coated with ethylcellulose (EC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565dd03fe489ec2501c98a3b4d7bfb46
https://doi.org/10.1016/j.ijpharm.2010.08.046
https://doi.org/10.1016/j.ijpharm.2010.08.046
Autor:
Angelina Yoo, Jakub Szlęk, Renata Jachowicz, Markus Thommes, Peter Kleinebudde, Aleksander Mendyk
Publikováno v:
European Journal of Pharmaceutical Sciences. 41:421-429
The objective was to prepare neural models identifying relationships between formulation characteristics and pellet properties based on algorithmic approach of crucial variables selection and neuro-fuzzy systems application. The database consisted of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f70e8d58e239aa3370c571e7e69598e
https://doi.org/10.1016/j.ejps.2010.07.010
https://doi.org/10.1016/j.ejps.2010.07.010