Azatriangulene-Based Conductive C═C Linked Covalent Organic Frameworks with Near-Infrared Emission.

Autor: Hamzehpoor E; Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec, H3A 09B, Canada., Ghamari P; Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec, H3A 09B, Canada., Tao Y; Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec, H3A 09B, Canada., Rafique MG; Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec, H3A 09B, Canada., Zhang Z; Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec, H3A 09B, Canada., Salehi M; Department of Chemical Engineering, McGill University, 3610 University Street, Montreal, Quebec, H3A 0C5, Canada., Stein RS; Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec, H3A 09B, Canada., Ramos-Sanchez J; Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec, H3A 09B, Canada., Laramée AW; Département de chimie, Institut Courtois, Université de Montréal, 1375 Avenue Thérèse-Lavoie-Roux, Montréal, Québec, H2V 0B3, Canada., Cosa G; Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec, H3A 09B, Canada., Pellerin C; Département de chimie, Institut Courtois, Université de Montréal, 1375 Avenue Thérèse-Lavoie-Roux, Montréal, Québec, H2V 0B3, Canada., Seifitokaldani A; Department of Chemical Engineering, McGill University, 3610 University Street, Montreal, Quebec, H3A 0C5, Canada., Khaliullin RZ; Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec, H3A 09B, Canada., Perepichka DF; Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec, H3A 09B, Canada.

Publikováno v: Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2024 Oct 21, pp. e2413629. Date of Electronic Publication: 2024 Oct 21.

Discovery of the Potent and Selective ATR Inhibitor Camonsertib (RP-3500).

Autor: Black WC; Repare Therapeutics, Inc., 7171 Frederick-Banting, Building 2, Saint-Laurent, Quebec H4S 1Z9, Canada., Abdoli A; Nuchem Sciences, Inc., 2350 Rue Cohen, Suite 201, Saint-Laurent, Quebec H4R 2N6, Canada., An X; New York Blood Center Enterprises, New York, New York 10065, United States., Auger A; Ventus Therapeutics, Inc., 7150 Frederick-Banting, Saint-Laurent, Quebec H4S 2A1, Canada., Beaulieu P; OmegaChem, 480 Rue Perreault, Lévis, Quebec G6W 7V6, Canada., Bernatchez M; OmegaChem, 480 Rue Perreault, Lévis, Quebec G6W 7V6, Canada., Caron C; Repare Therapeutics, Inc., 7171 Frederick-Banting, Building 2, Saint-Laurent, Quebec H4S 1Z9, Canada., Chefson A; Ventus Therapeutics, Inc., 7150 Frederick-Banting, Saint-Laurent, Quebec H4S 2A1, Canada., Crane S; Nuchem Sciences, Inc., 2350 Rue Cohen, Suite 201, Saint-Laurent, Quebec H4R 2N6, Canada., Diallo M; Repare Therapeutics, Inc., 7171 Frederick-Banting, Building 2, Saint-Laurent, Quebec H4S 1Z9, Canada., Dorich S; Ventus Therapeutics, Inc., 7150 Frederick-Banting, Saint-Laurent, Quebec H4S 2A1, Canada., Fader LD; Ventus Therapeutics, Inc., 7150 Frederick-Banting, Saint-Laurent, Quebec H4S 2A1, Canada., Ferraro GB; Repare Therapeutics, Inc., 7171 Frederick-Banting, Building 2, Saint-Laurent, Quebec H4S 1Z9, Canada., Fournier S; Repare Therapeutics, Inc., 7171 Frederick-Banting, Building 2, Saint-Laurent, Quebec H4S 1Z9, Canada., Gao Q; J-Star Research, Inc., 3001 Hadley Road, Suites 1-5A, South Plainfield, New Jersey 07080, United States., Ginzburg Y; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States., Hamel M; Repare Therapeutics, Inc., 7171 Frederick-Banting, Building 2, Saint-Laurent, Quebec H4S 1Z9, Canada., Han Y; New York Blood Center Enterprises, New York, New York 10065, United States., Jones P; Nuchem Sciences, Inc., 2350 Rue Cohen, Suite 201, Saint-Laurent, Quebec H4R 2N6, Canada., Lanoix S; Nuchem Sciences, Inc., 2350 Rue Cohen, Suite 201, Saint-Laurent, Quebec H4R 2N6, Canada., Lacbay CM; Nuchem Sciences, Inc., 2350 Rue Cohen, Suite 201, Saint-Laurent, Quebec H4R 2N6, Canada., Leclaire ME; Repare Therapeutics, Inc., 7171 Frederick-Banting, Building 2, Saint-Laurent, Quebec H4S 1Z9, Canada., Levy M; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States., Mamane Y; Repare Therapeutics, Inc., 7171 Frederick-Banting, Building 2, Saint-Laurent, Quebec H4S 1Z9, Canada., Mulani A; Nuchem Sciences, Inc., 2350 Rue Cohen, Suite 201, Saint-Laurent, Quebec H4R 2N6, Canada., Papp R; Repare Therapeutics, Inc., 7171 Frederick-Banting, Building 2, Saint-Laurent, Quebec H4S 1Z9, Canada., Pellerin C; Ventus Therapeutics, Inc., 7150 Frederick-Banting, Saint-Laurent, Quebec H4S 2A1, Canada., Picard A; Ventus Therapeutics, Inc., 7150 Frederick-Banting, Saint-Laurent, Quebec H4S 2A1, Canada., Skeldon A; Ventus Therapeutics, Inc., 7150 Frederick-Banting, Saint-Laurent, Quebec H4S 2A1, Canada., Skorey K; Nuchem Sciences, Inc., 2350 Rue Cohen, Suite 201, Saint-Laurent, Quebec H4R 2N6, Canada., Stocco R; Repare Therapeutics, Inc., 7171 Frederick-Banting, Building 2, Saint-Laurent, Quebec H4S 1Z9, Canada., St-Onge M; Ventus Therapeutics, Inc., 7150 Frederick-Banting, Saint-Laurent, Quebec H4S 2A1, Canada., Truchon JF; Repare Therapeutics, Inc., 7171 Frederick-Banting, Building 2, Saint-Laurent, Quebec H4S 1Z9, Canada., Truong VL; Nuchem Sciences, Inc., 2350 Rue Cohen, Suite 201, Saint-Laurent, Quebec H4R 2N6, Canada., Zimmermann M; Repare Therapeutics, Inc., 7171 Frederick-Banting, Building 2, Saint-Laurent, Quebec H4S 1Z9, Canada., Zinda M; Repare Therapeutics, Inc., 7171 Frederick-Banting, Building 2, Saint-Laurent, Quebec H4S 1Z9, Canada., Roulston A; Repare Therapeutics, Inc., 7171 Frederick-Banting, Building 2, Saint-Laurent, Quebec H4S 1Z9, Canada.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2024 Feb 22; Vol. 67 (4), pp. 2349-2368. Date of Electronic Publication: 2024 Feb 01.

Raman Analysis of Orientation and Crystallinity in High T g , Low Crystallinity Electrospun Fibers.

Autor: Laramée AW; Département de chimie, Université de Montréal, Montréal, QC, Canada., Pellerin C; Département de chimie, Université de Montréal, Montréal, QC, Canada.

Publikováno v: Applied spectroscopy [Appl Spectrosc] 2023 Nov; Vol. 77 (11), pp. 1289-1299. Date of Electronic Publication: 2023 Sep 29.

Identification of RP-6685 , an Orally Bioavailable Compound that Inhibits the DNA Polymerase Activity of Polθ.

Autor: Bubenik M; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Mader P; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario M5G 1X5, Canada., Mochirian P; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Vallée F; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Clark J; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Truchon JF; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Perryman AL; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Pau V; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario M5G 1X5, Canada., Kurinov I; Department of Chemistry and Chemical Biology, NE-CAT, Argonne, Cornell University, Illinois, New York 60439, United States., Zahn KE; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Leclaire ME; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Papp R; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Mathieu MC; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Hamel M; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Duffy NM; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Godbout C; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Casas-Selves M; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Falgueyret JP; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Baruah PS; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Nicolas O; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Stocco R; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Poirier H; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Martino G; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Fortin AB; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Roulston A; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Chefson A; Ventus Therapeutics, 7150 Frederick-Banting Suite 200, Montréal, Québec H4S 2A1, Canada., Dorich S; Ventus Therapeutics, 7150 Frederick-Banting Suite 200, Montréal, Québec H4S 2A1, Canada., St-Onge M; Ventus Therapeutics, 7150 Frederick-Banting Suite 200, Montréal, Québec H4S 2A1, Canada., Patel P; Ventus Therapeutics, 7150 Frederick-Banting Suite 200, Montréal, Québec H4S 2A1, Canada., Pellerin C; Ventus Therapeutics, 7150 Frederick-Banting Suite 200, Montréal, Québec H4S 2A1, Canada., Ciblat S; Ventus Therapeutics, 7150 Frederick-Banting Suite 200, Montréal, Québec H4S 2A1, Canada.; Paraza Pharma Inc., 2525 Ave. Marie Curie, Montréal, Québec H4S 1Z9, Canada., Pinter T; Ventus Therapeutics, 7150 Frederick-Banting Suite 200, Montréal, Québec H4S 2A1, Canada., Barabé F; Paraza Pharma Inc., 2525 Ave. Marie Curie, Montréal, Québec H4S 1Z9, Canada., El Bakkouri M; Paraza Pharma Inc., 2525 Ave. Marie Curie, Montréal, Québec H4S 1Z9, Canada.; National Research Council of Canada, 6100 Royalmount Avenue, Montréal, Québec H4P 2R2, Canada., Parikh P; Piramal Pharma Ltd., Plot No. 18, Village Matoda, Taluka: Sanand, Ahmedabad, Gujarat 382213, India., Gervais C; National Research Council of Canada, 6100 Royalmount Avenue, Montréal, Québec H4P 2R2, Canada., Sfeir A; Molecular Biology Program, Sloan Kettering Institute, MSKCC, 430 E 67th Street, New York, New York 10065, United States., Mamane Y; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Morris SJ; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Black WC; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada., Sicheri F; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario M5G 1X5, Canada., Gallant M; Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2022 Oct 13; Vol. 65 (19), pp. 13198-13215. Date of Electronic Publication: 2022 Sep 20.

Safety of subsequent general anaesthesia in patients allergic to neuromuscular blocking agents: value of allergy skin testing

Autor: Chiriac, A.M., Tacquard, C., Fadhel, N.B., Pellerin, C., Malinovsky, J.M., Mertes, P.M., Demoly, P.

Publikováno v: In British Journal of Anaesthesia June 2018 120(6):1437-1440