Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Pellegrino G. Magro"'
Autor:
Rowayda Peters, Angelo J. Russo, Jennifer Mandola, Wei-Wei Li, Zhen Hu, Joseph R. Bertino, Debabrata Banerjee, Pellegrino G. Magro
Publikováno v:
Cancer Research. 66:7253-7260
The E2F transcription factors play a critical role in coordinating transcription of specific genes essential for G1-S transition. In early G1, the retinoblastoma protein (pRB) becomes phosphorylated by cyclin-dependent kinases, disrupting pRB binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::903e859b30580f637d53f8410635972c
https://doi.org/10.1158/0008-5472.can-05-3725
https://doi.org/10.1158/0008-5472.can-05-3725
Publikováno v:
Cancer research. 70(21)
The multidrug resistance 1 gene (MDR1) encodes P-glycoprotein (Pgp), a member of the ATP-binding cassette (ABC) transporter family that confers tumor drug resistance by actively effluxing a number of antitumor agents. We had previously shown that MDR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1293fb207f023114242a5e6a8d2db82b
https://pubmed.ncbi.nlm.nih.gov/20861184
https://pubmed.ncbi.nlm.nih.gov/20861184
Publikováno v:
Cancer research. 64(12)
The p14ARF protein, the product of an alternate reading frame of the INK4A/ARF locus on human chromosome 9p21, disrupts the ability of MDM2 to target p53 for proteosomal degradation and causes an increase in steady-state p53 levels, leading to a G1 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b7082f562d932648dfeb774ec0753a
https://pubmed.ncbi.nlm.nih.gov/15205349
https://pubmed.ncbi.nlm.nih.gov/15205349