Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Pelin Ozfiliz Kilbas"'
Autor:
Pelin Ozfiliz Kilbas, Nisan Denizce Can, Tugba Kizilboga, Fikret Ezberci, Hamdi Levent Doganay, Elif Damla Arisan, Gizem Dinler Doganay
Publikováno v:
PLoS ONE, Vol 17, Iss 1 (2022)
Bag-1 protein is a crucial target in cancer to increase the survival and proliferation of cells. The Bag-1 expression is significantly upregulated in primary and metastatic cancer patients compared to normal breast tissue. Overexpression of Bag-1 dec
Externí odkaz:
https://doaj.org/article/f13417a6a2814ae79858e9f97aadee10
Autor:
Nisan Denizce Can, Ezgi Basturk, Tugba Kizilboga, Izzet Mehmet Akcay, Baran Dingiloglu, Ozge Tatli, Sevilay Acar, Pelin Ozfiliz Kilbas, Efe Elbeyli, Serena Muratcioglu, Ayse Tarbin Jannuzzi, Attila Gursoy, Ozlem Keskin, Hamdi Levent Doganay, Betul Karademir Yilmaz, Gizem Dinler Doganay
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0256640 (2021)
Bag-1 is a multifunctional protein that regulates Hsp70 chaperone activity, apoptosis, and proliferation. The three major Bag-1 isoforms have different subcellular localizations and partly non-overlapping functions. To identify the detailed interacti
Externí odkaz:
https://doaj.org/article/81c93148aa0b4ba2a4cb6391661ba753
Autor:
Miray Turk, Ozge Tatli, Hamza Furkan Alkan, Pelin Ozfiliz Kilbas, Gizem Alkurt, Gizem Dinler Doganay
Publikováno v:
Molecules, Vol 26, Iss 4, p 854 (2021)
Expression levels of the major mammalian autophagy regulator Beclin 1 and its interaction with Bcl-2 regulate the switch between autophagic cell survival and apoptotic cell death pathways. However, some of the regulators and the precise mechanisms of
Externí odkaz:
https://doaj.org/article/8e97b2af48d9470c8b696cf28d5b05c2
Autor:
Pelin Ozfiliz Kilbas, Ozlem Sonmez, Pinar Uysal-Onganer, Ajda Coker Gurkan, Pinar Obakan Yerlikaya, Elif Damla Arisan
Publikováno v:
Biology, Vol 9, Iss 10, p 320 (2020)
Paclitaxel (PTX) is a widely used chemotherapeutic agent in the treatment of breast cancer, and resistance to PTX is a common failure of breast cancer therapy. Therefore, understanding the effective molecular targets in PTX-resistance gains importanc
Externí odkaz:
https://doaj.org/article/f3225cddd9c344dba62d81f5a3acc80a
Autor:
Sina Kashani, Pelin Ozfiliz Kilbas, Pinar Obakan Yerlikaya, Ajda Coker Gurkan, Elif Damla Arisan
Publikováno v:
Proceedings, Vol 40, Iss 1, p 42 (2020)
Prostate cancer is the second common cause of death among men worldwide. In the treatment of prostate cancer, conventional chemotherapeutics are commonly used. The plant alkaloid Paclitaxel and platinum-based cisplatin are the most common chemotherap
Externí odkaz:
https://doaj.org/article/87f271a934194af797af9f077e0eec40
Publikováno v:
Molecular Biology Reports. 46:847-860
The multifunctional anti-apoptotic Bag-1 protein has important roles in apoptosis, proteasome-mediated degradation, transcriptional regulation, and intracellular signaling. Bag-1 promotes cell survival and proliferation, and is overexpressed in breas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d17e3ed629ec0ff663411263d422d3ee
https://doi.org/10.1007/s11033-018-4540-x
https://doi.org/10.1007/s11033-018-4540-x
Autor:
Pelin Ozfiliz Kilbas, Nisan Denizce Can, Tugba Kizilboga, Fikret Ezberci, Hamdi Levent Doganay, Elif Damla Arisan, Gizem Dinler Doganay
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 1, p e0261062 (2022)
PLoS ONE, Vol 17, Iss 1 (2022)
PLoS ONE, Vol 17, Iss 1, p e0261062 (2022)
PLoS ONE, Vol 17, Iss 1 (2022)
Bag-1 protein is a crucial target in cancer to increase the survival and proliferation of cells. The Bag-1 expression is significantly upregulated in primary and metastatic cancer patients compared to normal breast tissue. Overexpression of Bag-1 dec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65499369304750c0a94600eea285ba5a
https://pubmed.ncbi.nlm.nih.gov/34995286
https://pubmed.ncbi.nlm.nih.gov/34995286
Autor:
Narcin Palavan-Unsal, Pınar Obakan-Yerlikaya, Ozlem Sonmez, Ajda Coker-Gurkan, Elif Damla Arisan, Pinar Uysal-Onganer, Pelin Ozfiliz-Kilbas
Publikováno v:
Cancers
Volume 13
Issue 21
Cancers, Vol 13, Iss 5322, p 5322 (2021)
Volume 13
Issue 21
Cancers, Vol 13, Iss 5322, p 5322 (2021)
Simple Summary: Altered metabolic pathways determine the aggressivity of breast cancer cells. To highlight the potential markers gains importance to understand early molecular signatures of disease. microRNAs are the small non-coding RNAs found in di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::217b56081cecf6a91b6f0c4ab7b99b60
https://doi.org/10.3390/cancers13215322
https://doi.org/10.3390/cancers13215322
Autor:
Elif Damla Arisan, Ajda Çoker Gürkan, Pelin Ozfiliz Kilbas, Pınar Obakan Yerlikaya, Sina Kashani
Publikováno v:
Proceedings, Vol 40, Iss 1, p 42 (2020)
Prostate cancer is the second common cause of death among men worldwide. In the treatment of prostate cancer, conventional chemotherapeutics are commonly used. The plant alkaloid Paclitaxel and platinum-based cisplatin are the most common chemotherap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d85c97a0f4d3556c8d9ca20b886a63
https://doi.org/10.3390/proceedings2019040042
https://doi.org/10.3390/proceedings2019040042
Autor:
Elif Damla Arisan, Pelin Ozfiliz Kilbas, Pinar Uysal-Onganer, Ozlem Sonmez, Pınar Obakan Yerlikaya, Ajda Çoker Gürkan
Publikováno v:
Biology
Volume 9
Issue 10
Biology, Vol 9, Iss 320, p 320 (2020)
Volume 9
Issue 10
Biology, Vol 9, Iss 320, p 320 (2020)
Simple Summary Investigation into effective targets of drug resistance is important for identifying novel strategies in cancer therapy. The study aimed to determine the functional role of paclitaxel (PTX) resistance on MCF-7 cell survival related to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f930139d091f1d2ed29e2492a907cd
https://doi.org/10.3390/biology9100320
https://doi.org/10.3390/biology9100320