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Utility investigation of automated techniques in hematopoietic progenitor cell count and viability assessment in the Good Manufacturing Practice (GMP) setting

Autor: Şükran Şeker, Klara Dalva, Orkun Cevheroğlu, Oznur Coskun, Aydin Ozturk, Pelin Kilic, Ayşe Eser Elçin, Ozge Lalegul Ulker, Pinar Baydin, Açelya Yilmazer, Mahmut Parmaksiz, Senay Ipek, Gunseli Cubukcuoglu Deniz, Meltem Bay, Gunhan Gurman, Ceylan Verda Bitirim

Publikováno v: EXPERIMENTAL BIOMEDICAL RESEARCH; Vol 3 No 4 (2020): Experimental Biomedical Research; 231-238

Aim: To compare our parameters as regards: i) cell count via two different automated cell count techniques, and ii) viability via automated trypan blue exclusion and 7-aminoactinomycin D (7-AAD) staining. Method: We used the trypan blue exclusion tec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31875b30e2ac031a07fd35db8bbbb4ef
https://doi.org/10.30714/j-ebr.2020463606

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Quality Management Systems (QMSs) of Human-Based Tissue and Cell Product Manufacturing Facilities

Autor: Pelin, Kilic

Publikováno v: Methods in molecular biology (Clifton, N.J.). 2286

In the broadest sense, a quality management system (QMS) runs by continuous interaction of elements based on processes, procedures, policies, guidelines, and resources that are compiled to guide an organization under the scope of its operational miss

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::542e13c737fbb5a65327dad815e5f98e
https://pubmed.ncbi.nlm.nih.gov/33543429

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Quality Management Systems (QMSs) of Human-Based Tissue and Cell Product Manufacturing Facilities

Autor: Pelin Kilic

Publikováno v: Methods in Molecular Biology ISBN: 9781071613269

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7bca27a98516b13a9cf97c46c1a89ff4
https://doi.org/10.1007/7651_2020_341

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Named Entity Recognition on Morphologically Rich Language: Exploring the Performance of BERT with varying Training Levels

Autor: Pinar Karagoz, Yuksel Pelin Kilic, Duygu Dinc

Publikováno v: IEEE BigData

Named Entity Recognition (NER) is an information extraction task that aims to automatically identify named entities in a given text. Named entities are special types of nouns or noun groups that refer to specific entities including as person, locatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4b994cd6bead4c63a5255f156a147129
https://doi.org/10.1109/bigdata50022.2020.9377869

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Understanding factors affecting human chondrocyte culturing: an experimental study

Autor: Pelin Kilic, Açelya Yilmazer, Gunhan Gurman, Cansu Gurcan

Publikováno v: Cell and tissue banking. 21(4)

Over the years, surgical strategies have been developed in hope of full regeneration of the injured cartilage. In our study, we aimed to develop an optimized chondrocyte culture isolation technique as an active ingredient of a standardized autologous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc5ce4401ee721bbfebcb8d0f70531a8
https://pubmed.ncbi.nlm.nih.gov/32671509

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Where is human-based cellular pharmaceutical R&D taking us in cartilage regeneration?

Autor: Pelin Kilic, Cansu Gurcan, Damla Alkaya, Açelya Yilmazer, Gunhan Gurman

Publikováno v: 3 Biotech

Lately, cellular-based cartilage joint therapies have gradually gained more attention, which leads to next generation bioengineering approaches in the development of cell-based medicinal products for human use in cartilage repair. The greatest hurdle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbaa6e22f97fcd0153fc50cec7cc199f
https://europepmc.org/articles/PMC7060299/

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A CD34+ Cell Enrichment Protocol of Hematopoietic Stem Cells in a Well-Established Quality Management System

Autor: Ayşe Eser Elçin, Açelya Yilmazer, Pinar Baydin, Yasin Yildirim, Şükran Şeker, Osman Ilhan, Meltem Bay, Gunhan Gurman, Ozge Lalegul Ulker, Mahmut Parmaksiz, Oznur Coskun, Pelin Kilic, Kamil Can Akcali, Gunseli Cubukcuoglu Deniz, Klara Dalva

Publikováno v: Cells, tissues, organs. 207(1)

Allogeneic stem cell transplantation applications have improved tremendously over the past quarter of a century. The use of new immunosuppressive protocols and elimination of T cells by CD34+ cell enrichment or T cell depletion on apheresis products

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::980e287e2b4b1df16ab25368b080949f
https://pubmed.ncbi.nlm.nih.gov/31357194

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