Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Pele Chong"'
Autor:
Hsiao-Yun Shao, Juo-Yu Huang, Yi-Wen Lin, Shu-Ling Yu, Ebenezer Chitra, Ching-Kun Chang, Wang-Chou Sung, Pele Chong, Yen-Hung Chow
Publikováno v:
International Journal of Infectious Diseases, Vol 41, Iss C, Pp 56-64 (2015)
Objectives: The regulation of the immunopathology of respiratory syncytial virus (RSV) by regulatory T-cells (CD4+CD25+Foxp3+; Tregs) is not understood. Methods: To deduce the same, Tregs were depleted in BALB/c mice by injecting anti-CD25 antibody f
Externí odkaz:
https://doaj.org/article/f9b2d845cfc2494aaf1e0e9a5a3ce482
Autor:
Yueh-Liang Tsou, Yi-Wen Lin, Hsiao-Yun Shao, Shu-Ling Yu, Shang-Rung Wu, Hsiao-Yu Lin, Chia-Chyi Liu, Chieh Huang, Pele Chong, Yen-Hung Chow
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 4, p e0003692 (2015)
Enterovirus 71 (EV71) and coxsackieviruses (CV) are the major causative agents of hand, foot and mouth disease (HFMD). There is not currently a vaccine available against HFMD, even though a newly developed formalin-inactivated EV71 (FI-EV71) vaccine
Externí odkaz:
https://doaj.org/article/e615ce527757405895e928fb2abad072
Autor:
Hsin-Wei Chen, Hui-Mei Hu, Szu-Hsien Wu, Chen-Yi Chiang, Yu-Ju Hsiao, Chia-Kai Wu, Chun-Hsiang Hsieh, Han-Hsuan Chung, Pele Chong, Chih-Hsiang Leng, Chien-Hsiung Pan
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145717 (2015)
Dengue is the leading cause of mosquito-borne viral infections and no vaccine is available now. Envelope protein domain III (ED3) is the major target for the binding of dengue virus neutralizing antibodies; however, the ED3-specifc T-cell response is
Externí odkaz:
https://doaj.org/article/03bb7c0712d04005b1336f7f13448a16
Autor:
Chia-Chyi Liu, Chyi-Sing Hwang, Wun-Syue Yang, Dan-Chin Tsai, Sze-Hsien Wu, Ai-Hsiang Chou, Yen-Hung Chow, Suh-Chin Wu, Jen-Ren Wang, Jen-Ron Chiang, Chin-Cheng Huang, Chien-Hsiung Pan, Pele Chong
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106756 (2014)
Enterovirus 71 (EV71) has caused epidemics of hand, foot and mouth diseases in Asia during the past decades and no vaccine is available. A formalin-inactivated EV71 candidate vaccine (EV71vac) based on B4 subgenotype has previously been developed and
Externí odkaz:
https://doaj.org/article/d77af39062a048e9859fa2c0fabdb411
Autor:
Chen-Yi Chiang, Chien-Hsiung Pan, Chun-Hsiang Hsieh, Jy-Ping Tsai, Mei-Yu Chen, Hsueh-Hung Liu, Shih-Jen Liu, Pele Chong, Chih-Hsiang Leng, Hsin-Wei Chen
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 9, p e2432 (2013)
BACKGROUND: Dengue virus is a mosquito-transmitted virus that can cause self-limiting dengue fever, severe life-threatening dengue hemorrhagic fever and dengue shock syndrome. The existence of four serotypes of dengue virus has complicated the develo
Externí odkaz:
https://doaj.org/article/89c70b8ff91d4c39a42ce5f0b44215b0
Autor:
Yi-Wen Lin, Shu-Ling Yu, Hsiao-Yun Shao, Hsiang-Yin Lin, Chia-Chyi Liu, Kuang-Nan Hsiao, Ebenezer Chitra, Yueh-Liang Tsou, Hsuen-Wen Chang, Charles Sia, Pele Chong, Yen-Hung Chow
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57591 (2013)
Enterovirus 71 (EV71) and coxsackievirus (CVA) are the most common causative factors for hand, foot, and mouth disease (HFMD) and neurological disorders in children. Lack of a reliable animal model is an issue in investigating EV71-induced disease ma
Externí odkaz:
https://doaj.org/article/a07204f5a28f49109e2bd68a1a2771e3
Autor:
Hsuen-Wen Chang, Yi-Wen Lin, Hui-Min Ho, Min-Han Lin, Chia-Chyi Liu, Hsiao-Yun Shao, Pele Chong, Charles Sia, Yen-Hung Chow
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69858 (2013)
Hand-foot-mouth diseases (HFMD) caused by enterovirus 71 (EV71) and coxsackievirus 16 (CVA16) in children have now become a severe public health issue in the Asian-Pacific region. Recently we have successfully developed transgenic mice expressing hum
Externí odkaz:
https://doaj.org/article/6bade2f9c7e14f6b91d00fa5cc79d5cf
Autor:
Chen-Yi Chiang, Ming-Hsi Huang, Chun-Hsiang Hsieh, Mei-Yu Chen, Hsueh-Hung Liu, Jy-Ping Tsai, Yi-Shiuan Li, Ching-Yun Chang, Shih-Jen Liu, Pele Chong, Chih-Hsiang Leng, Hsin-Wei Chen
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 5, p e1645 (2012)
The major weaknesses of subunit vaccines are their low immunogenicity and poor efficacy. Adjuvants can help to overcome some of these inherent defects with subunit vaccines. Here, we evaluated the efficacy of the newly developed water-in-oil-in-water
Externí odkaz:
https://doaj.org/article/27772dfe94284c2c80097403d3bc8ef0
Autor:
Ai-Hsiang Chou, Chia-Chyi Liu, Cheng-Peng Chang, Meng-Shin Guo, Shih-Yang Hsieh, Wen-Hsueh Yang, Hsin-Ju Chao, Chien-Long Wu, Ju-Lan Huang, Min-Shi Lee, Alan Yung-Chi Hu, Sue-Chen Lin, Yu-Yun Huang, Mei-Hua Hu, Yen-Hung Chow, Jen-Ron Chiang, Jui-Yuan Chang, Pele Chong
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34834 (2012)
BACKGROUND: Enterovirus 71 (EV71) has caused several epidemics of hand, foot and mouth diseases (HFMD) in Asia and now is being recognized as an important neurotropic virus. Effective medications and prophylactic vaccine against EV71 infection are ur
Externí odkaz:
https://doaj.org/article/3c324a36e7794b5d982598f7648f7b6a
Autor:
Chiung-Yi Huang, Jeremy J W Chen, Kuan-Yin Shen, Li-Sheng Chang, Yi-Chen Yeh, I-Hua Chen, Pele Chong, Shih-Jen Liu, Chih-Hsiang Leng
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40970 (2012)
The E7 oncoprotein of human papillomavirus (HPV) is an ideal target for developing immunotherapeutic strategies against HPV-associated tumors. However, because protein-based immunogens alone are poor elicitors of the cytotoxic T-lymphocyte (CTL) resp
Externí odkaz:
https://doaj.org/article/f577e7b5d858402f807e6a3f6bad7d71