Association of Peripheral Insulin Resistance and Other Markers of Type 2 Diabetes Mellitus with Brain Amyloid Deposition in Healthy Individuals at Risk of Dementia

Autor: Pekkala, T., Hall, A., Mangialasche, F., Kemppainen, N., Mecocci, P., Ngandu, T., Rinne, J. O., Soininen, H., Tuomilehto, J., Kivipelto, M., Solomon, A., Ashford, J. W.

Publikováno v: Journal of Alzheimer's Disease

We explored the association of type 2 diabetes related blood markers with brain amyloid accumulation on PiB-PET scans in 41 participants from the FINGER PET sub-study. We built logistic regression models for brain amyloid status with12 plasma markers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c8ce8111585d6ede25ba594fd76283b0
https://pubmed.ncbi.nlm.nih.gov/32623394

Insights into Preservation of Blood Biomarkers in Biobank Samples.

Autor: Juurikka K; Cancer and Translational Medicine Research Unit, University of Oulu, Oulu, Finland.; Medical Research Center, Oulu University Hospital and University of Oulu, Oulu, Finland., Åström P; The Research Unit of Biomedicine, University of Oulu, Oulu, Finland., Pekkala T; Biobank Borealis of Northern Finland, Oulu University Hospital, Oulu, Finland., Öhman H; Biobank Borealis of Northern Finland, Oulu University Hospital, Oulu, Finland.; Faculty of Medicine, University of Oulu, Oulu, Finland., Sorsa T; Department of Oral and Maxillofacial Diseases, Head and Neck Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Division of Periodontology, Department of Dental Medicine, Karolinska Institute, Stockholm, Sweden., Tervahartiala T; Department of Oral and Maxillofacial Diseases, Head and Neck Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Salo T; Cancer and Translational Medicine Research Unit, University of Oulu, Oulu, Finland.; Medical Research Center, Oulu University Hospital and University of Oulu, Oulu, Finland.; Department of Oral and Maxillofacial Diseases, Head and Neck Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Translational Immunology Research Program (TRIMM), University of Helsinki, Helsinki, Finland., Lehenkari P; Cancer and Translational Medicine Research Unit, University of Oulu, Oulu, Finland.; Medical Research Center, Oulu University Hospital and University of Oulu, Oulu, Finland., Nyberg P; Cancer and Translational Medicine Research Unit, University of Oulu, Oulu, Finland.; Medical Research Center, Oulu University Hospital and University of Oulu, Oulu, Finland.; Biobank Borealis of Northern Finland, Oulu University Hospital, Oulu, Finland.

Publikováno v: Biopreservation and biobanking [Biopreserv Biobank] 2022 Jun; Vol. 20 (3), pp. 297-301. Date of Electronic Publication: 2022 Jan 11.

Detecting Amyloid Positivity in Elderly With Increased Risk of Cognitive Decline.

Autor: Pekkala T; Institute of Clinical Medicine/Neurology, University of Eastern Finland, Kuopio, Finland., Hall A; Institute of Clinical Medicine/Neurology, University of Eastern Finland, Kuopio, Finland., Ngandu T; Public Health Promotion Unit, Finnish Institute for Health and Welfare, Helsinki, Finland.; Division of Clinical Geriatrics, Center for Alzheimer Research, NVS, Karolinska Institutet, Stockholm, Sweden., van Gils M; VTT Technical Research Centre of Finland Ltd., Tampere, Finland., Helisalmi S; Institute of Clinical Medicine/Neurology, University of Eastern Finland, Kuopio, Finland., Hänninen T; Neurocenter/Neurology, Kuopio University Hospital, Kuopio, Finland., Kemppainen N; Turku PET Centre, University of Turku, Turku, Finland.; Division of Clinical Neurosciences, Turku University Hospital, Turku, Finland., Liu Y; Institute of Clinical Medicine/Neurology, University of Eastern Finland, Kuopio, Finland.; Department of Clinical Radiology, Kuopio University Hospital, Kuopio, Finland., Lötjönen J; Combinostics, Tampere, Finland., Paajanen T; Finnish Institute of Occupational Health, Helsinki, Finland., Rinne JO; Turku PET Centre, University of Turku, Turku, Finland.; Division of Clinical Neurosciences, Turku University Hospital, Turku, Finland., Soininen H; Institute of Clinical Medicine/Neurology, University of Eastern Finland, Kuopio, Finland.; Neurocenter/Neurology, Kuopio University Hospital, Kuopio, Finland., Kivipelto M; Institute of Clinical Medicine/Neurology, University of Eastern Finland, Kuopio, Finland.; Division of Clinical Geriatrics, Center for Alzheimer Research, NVS, Karolinska Institutet, Stockholm, Sweden.; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.; Ageing Epidemiology Research Unit, School of Public Health, Imperial College London, London, United Kingdom., Solomon A; Institute of Clinical Medicine/Neurology, University of Eastern Finland, Kuopio, Finland.; Division of Clinical Geriatrics, Center for Alzheimer Research, NVS, Karolinska Institutet, Stockholm, Sweden.

Publikováno v: Frontiers in aging neuroscience [Front Aging Neurosci] 2020 Jul 30; Vol. 12, pp. 228. Date of Electronic Publication: 2020 Jul 30 (Print Publication: 2020).

Non-Receptor Tyrosine Kinases: Their Structure and Mechanistic Role in Tumor Progression and Resistance.

Autor: Eshaq, Abdulaziz M.^1,2 (AUTHOR) eshaq@gwu.edu, Flanagan, Thomas W.³ (AUTHOR) tflan1@lsuhsc.edu, Hassan, Sofie-Yasmin⁴ (AUTHOR) sofie00@gmx.de, Al Asheikh, Sara A.² (AUTHOR) walamoudi@alfaisal.edu, Al-Amoudi, Waleed A.² (AUTHOR) maryam.o.alamodi@gmail.com, Santourlidis, Simeon⁵ (AUTHOR) simeon.santourlidis@med.uni-duesseldorf.de, Hassan, Sarah-Lilly⁶ (AUTHOR) saha109@hhu.de, Alamodi, Maryam O.² (AUTHOR) m.alamodi1998@gmail.com, Bendhack, Marcelo L.⁷ (AUTHOR) marcelo@uro-onco.net, Alamodi, Mohammed O.² (AUTHOR), Haikel, Youssef^8,9,10 (AUTHOR) youssef.haikel@unistra.fr, Megahed, Mossad¹¹ (AUTHOR) mmegahed@ukaachen.de, Hassan, Mohamed^8,9,12 (AUTHOR) dr.hassan@gmx.de

Publikováno v: Cancers. Aug2024, Vol. 16 Issue 15, p2754. 34p.

Computerized decision support is an effective approach to select memory clinic patients for amyloid-PET.

Autor: Rhodius-Meester, Hanneke F. M.^1,2,3,4 (AUTHOR) h.rhodius@amsterdamumc.nl, van Maurik, Ingrid S.^1,2,5,6 (AUTHOR), Collij, Lyduine E.⁷ (AUTHOR), van Gils, Aniek M.^1,2 (AUTHOR), Koikkalainen, Juha⁸ (AUTHOR), Tolonen, Antti⁸ (AUTHOR), Pijnenburg, Yolande A. L.^1,2 (AUTHOR), Berkhof, Johannes^5,6 (AUTHOR), Barkhof, Frederik^7,9 (AUTHOR), van de Giessen, Elsmarieke^1,2,7 (AUTHOR), Lötjönen, Jyrki⁸ (AUTHOR), van der Flier, Wiesje M.^1,2,5,6 (AUTHOR)

Publikováno v: PLoS ONE. 5/20/2024, Vol. 19 Issue 5, p1-17. 17p.