Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Pekka Patrikainen"'
Autor:
Kati Thiel, Pekka Patrikainen, Csaba Nagy, Duncan Fitzpatrick, Nicolas Pope, Eva-Mari Aro, Pauli Kallio
Publikováno v:
Microbial Cell Factories, Vol 18, Iss 1, Pp 1-16 (2019)
Abstract Background Oxygen-evolving photoautotrophic organisms, like cyanobacteria, protect their photosynthetic machinery by a number of regulatory mechanisms, including alternative electron transfer pathways. Despite the importance in modulating th
Externí odkaz:
https://doaj.org/article/f845a85417b54611a198d07211c342ec
Publikováno v:
Metabolic Engineering Communications, Vol 5, Iss C, Pp 9-18 (2017)
Aldehyde deformylating oxygenase (ADO) is a unique enzyme found exclusively in photosynthetic cyanobacteria, which natively converts acyl aldehyde precursors into hydrocarbon products embedded in cellular lipid bilayers. This capacity has opened door
Externí odkaz:
https://doaj.org/article/869533c5081a4f10a5935bfb376b7ed1
Autor:
Pasi Paananen, Jarmo Niemi, Pekka Mäntsälä, Mikko Metsä-Ketelä, Pauli Kallio, Pekka Patrikainen, Laila Niiranen
Publikováno v:
Biochemistry. 52(31):5304-5314
Angucyclines are biologically active natural products constructed around a common benz[a]anthraquinone carbon frame. One key branching point in the biosynthesis of angucyclines is the ketoreduction at C-6, which results in the opposite stereochemistr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2b393b69137d13e82a3457747ceca38
https://doi.org/10.1021/bi400712q
https://doi.org/10.1021/bi400712q
Autor:
Anna-Maria Brandt, Henri Niskanen, Vimal Parkash, Jyrki Heino, Jarmo Käpylä, Tiina A. Salminen, Matti Lahti, Eva Bligt, Pekka Patrikainen, Johanna Jokinen
Publikováno v:
Journal of Biological Chemistry. 286:43343-43351
We have analyzed the structure and function of the integrin α(1)I domain harboring a gain-of-function mutation E317A. To promote protein crystallization, a double variant with an additional C139S mutation was used. In cell adhesion assays, the E317A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05deb18d1b9d77e40515e7a00eef7ded
https://doi.org/10.1074/jbc.m111.261909
https://doi.org/10.1074/jbc.m111.261909
Autor:
Pauli Kallio, Jukka-Pekka Suomela, Pekka Patrikainen, Pekka Mäntsälä, Mikko Metsä-Ketelä, Jarmo Niemi
Publikováno v:
Biochemistry. 50:5535-5543
A simplified model system composed of a NADPH-dependent flavoprotein hydroxylase PgaE and a short-chain alcohol dehydrogenase/reductase (SDR) CabV was used to dissect a multistep angucycline modification redox cascade into several subreactions in vit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cc24a18a6a68cc293f1d313f2758093
https://doi.org/10.1021/bi200600k
https://doi.org/10.1021/bi200600k
Autor:
Jarmo Niemi, Pekka Mäntsälä, Mikko Metsä-Ketelä, Pauli Kallio, Keqian Yang, Pekka Patrikainen, Georgiy A. Belogurov
Publikováno v:
Biochemistry. 52(26)
Two functionally distinct homologous flavoprotein hydroxylases, PgaE and JadH, have been identified as branching points in the biosynthesis of the polyketide antibiotics gaudimycin C and jadomycin A, respectively. These evolutionarily related enzymes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d460f9537170f62104183cf82123e7d
https://pubmed.ncbi.nlm.nih.gov/23731237
https://pubmed.ncbi.nlm.nih.gov/23731237
Autor:
Karel D. Klika, Jarmo Niemi, Pekka Patrikainen, Keqiang Fan, Khaled A. Shaaban, Pekka Mäntsälä, Mikko Metsä-Ketelä, Pauli Kallio, Jürgen Rohr, Keqian Yang
Publikováno v:
Chemistry & Biology. (5):647-655
SummaryComparison of homologous angucycline modification enzymes from five closely related Streptomyces pathways (pga, cab, jad, urd, lan) allowed us to deduce the biosynthetic steps responsible for the three alternative outcomes: gaudimycin C, dehyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb9ed2e0356379395a1e9c5aba52f8e8
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.