Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Pekka Mali"'
Publikováno v:
Duodecim; laaketieteellinen aikakauskirja. 132(6)
In addition to conventional cytotoxic agents, novel drug treatments have in the last few years been introduced for the treatment of non-small cell lung cancer. Whereas some of the novel treatments have brought significant improvement in treatment out
Publikováno v:
International Journal of Clinical Medicine. :346-351
This phase II study assessed the clinical response and short-term quality of life of patients receiving first-line chemotherapy with epirubicin-docetaxel combination for metastatic breast cancer. Thirty-one breast cancer patients were treated with ep
Autor:
Maria Sundvall, Pekka Mali, Mika Savisalo, Teemu T. Junttila, Reidar Grénman, Klaus Elenius, Kaisa Erjala, Jarmo Kulmala, Na Zhang, Jaakko Pulkkinen
Publikováno v:
Clinical Cancer Research. 12:4103-4111
Purpose: The epidermal growth factor receptor (EGFR) inhibitor gefitinib (Iressa) has shown antitumor activity in clinical trials against cancers, such as non–small cell lung cancer and head and neck squamous cell carcinoma (HNSCC). Research on non
Autor:
D. Aubert, Pekka Mali, J. Terrassa Pons, Christian Manegold, Miklos Pless, D. Betticher, F. De Marinis, C. Gridelli, Martin Reck, Y. Parlier, Rolf A. Stahel, J.-P. Burillon, L. Portalone, O. Castelnau
Publikováno v:
European Journal of Cancer. 40:2424-2431
Vinorelbine intravenously (i.v.) demonstrated its efficacy and tolerability in advanced non-small cell lung cancer (NSCLC) patients, including elderly subjects. Since vinorelbine is now available as an oral formulation this phase II open study was de
Autor:
Leena Kivisaari, Maija Halme, Tiina Ollikainen, Aija Knuuttila, Pekka Mali, Karin Mattson, Kaija Linnainmaa, Antti Jekunen
Publikováno v:
Anti-Cancer Drugs. 11:257-261
We chose to treat malignant pleural mesothelioma with a combination of docetaxel and irinotecan (CPT-11), because there have been preliminary reports that CPT-11 is active against mesothelioma, and docetaxel and CPT-11 were the most active agents in
Publikováno v:
Duodecim; laaketieteellinen aikakauskirja. 128(21)
Nearly half of all lung cancers are adenocarcinomas falling into various subtypes. Other common types of lung cancer include squamous cell carcinoma and small cell carcinoma. The pathogenesis and molecular biology of lung cancer has been the subject
Publikováno v:
Biology of Reproduction. 53:499-510
The temporal and spatial expression of thirteen novel spermatid-specific genes corresponding to cDNA clones isolated from an adult mouse testis library was analyzed. Northern analysis of RNA from seminiferous tubules at defined stages of the rat and
Publikováno v:
Molecular and Cellular Endocrinology. 113:175-181
Cyclic protein-2/cathepsin L (CP-2) is secreted by Sertoli cells in a highly stage-specific manner, maximally during stages VI-VII of the rat seminiferous epithelial cycle. We investigated FSH regulation of CP-2 mRNA expression of its cellular locali
Publikováno v:
Radiation Oncology (London, England)
Radiation Oncology, Vol 7, Iss 1, p 79 (2012)
Radiation Oncology, Vol 7, Iss 1, p 79 (2012)
Background and purpose Stereotactic lung radiotherapy (SLRT) has emerged as a curative treatment for medically inoperable patients with early-stage non-small cell lung cancer (NSCLC) and the use of intensity-modulated radiotherapy (IMRT) and volumetr
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 74(2)
Erlotinib is a highly potent inhibitor of epidermal growth factor receptor tyrosine-kinase activity that significantly prolongs overall survival in patients with non-small-cell lung cancer (NSCLC), and improves symptom control and quality of life com