Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Pekka Katajisto"'
Autor:
Tom Barsby, Eliisa Vähäkangas, Jarkko Ustinov, Hossam Montaser, Hazem Ibrahim, Väinö Lithovius, Emilia Kuuluvainen, Vikash Chandra, Jonna Saarimäki-Vire, Pekka Katajisto, Ville Hietakangas, Timo Otonkoski
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112970- (2023)
Summary: Pancreatic islets regulate blood glucose homeostasis through the controlled release of insulin; however, current metabolic models of glucose-sensitive insulin secretion are incomplete. A comprehensive understanding of islet metabolism is int
Externí odkaz:
https://doaj.org/article/ce7f7f087e48409ea41c81a3c021754a
Autor:
Toni T. Lemmetyinen, Emma W. Viitala, Linnea Wartiovaara, Tuomas Kaprio, Jaana Hagström, Caj Haglund, Pekka Katajisto, Timothy C. Wang, Eva Domènech-Moreno, Saara Ollila
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 4 (2023)
Externí odkaz:
https://doaj.org/article/ed2fb70acff64aa0b0a827344937d4ff
Autor:
Mara Martín-Alonso, Sharif Iqbal, Pia M. Vornewald, Håvard T. Lindholm, Mirjam J. Damen, Fernando Martínez, Sigrid Hoel, Alberto Díez-Sánchez, Maarten Altelaar, Pekka Katajisto, Alicia G. Arroyo, Menno J. Oudhoff
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
While the role of smooth muscle in peristalsis has been studied extensively, little is known about its other functions in the intestine. Here the authors identify MMP17, expressed by smooth muscle cells, as a modulator of intestinal epithelial regene
Externí odkaz:
https://doaj.org/article/8dd66dd807d54c32a63b16e262a5ef10
Publikováno v:
Frontiers in Computer Science, Vol 4 (2022)
Techniques to acquire and analyze biological images are central to life science. However, the workflow downstream of imaging can be complex and involve several tools, leading to creation of very specialized scripts and pipelines that are difficult to
Externí odkaz:
https://doaj.org/article/1d65bcbbc5704877b006d2bf597fd2af
Autor:
Joel Johnson George, Mikko Oittinen, Laura Martin-Diaz, Veronika Zapilko, Sharif Iqbal, Terhi Rintakangas, Fábio Tadeu Arrojo Martins, Henri Niskanen, Pekka Katajisto, Minna U. Kaikkonen, Keijo Viiri
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 873-889 (2021)
Background & Aims: Microfold cells (M cells) are immunosurveillance epithelial cells located in the Peyer’s patches (PPs) in the intestine and are responsible for monitoring and transcytosis of antigens, microorganisms, and pathogens. Mature M cell
Externí odkaz:
https://doaj.org/article/7d3af4b16f85404c962fbd3a9b4b2aeb
Autor:
Maria Azkanaz, Bernat Corominas-Murtra, Saskia I. J. Ellenbroek, Lotte Bruens, Anna T. Webb, Dimitrios Laskaris, Koen C. Oost, Simona J. A. Lafirenze, Karl Annusver, Hendrik A. Messal, Sharif Iqbal, Dustin J. Flanagan, David J. Huels, Felipe Rojas-Rodríguez, Miguel Vizoso, Maria Kasper, Owen J. Sansom, Hugo J. Snippert, Prisca Liberali, Benjamin D. Simons, Pekka Katajisto, Edouard Hannezo, Jacco van Rheenen
Publikováno v:
Nature, 607(7919), 548-554. Nature Publishing Group
Nature
Nature
The morphology and functionality of the epithelial lining differ along the intestinal tract, but tissue renewal at all sites is driven by stem cells at the base of crypts(1-3). Whether stem cell numbers and behaviour vary at different sites is unknow
Autor:
Laura Hakanpää, Amr Abouelezz, An-Sofie Lenaerts, Seyda Culfa, Michael Algie, Jenny Bärlund, Pekka Katajisto, Harvey McMahon, Leonardo Almeida-Souza
Publikováno v:
Journal of Cell Biology. 222
Reticular adhesions (RAs) consist of integrin αvβ5 and harbor flat clathrin lattices (FCLs), long-lasting structures with similar molecular composition as clathrin-mediated endocytosis (CME) carriers. Why FCLs and RAs colocalize is not known. Here,
Autor:
Sandra Scharaw, Agustin Sola-Carvajal, Ilya Belevich, Anna T. Webb, Srustidhar Das, Simon Andersson, Nalle Pentinmikko, Eduardo J. Villablanca, James R. Goldenring, Eija Jokitalo, Robert J. Coffey, Pekka Katajisto
Publikováno v:
bioRxiv
Cell-to-cell signalling between niche and stem cells regulates tissue regeneration. While the identity of many mediating factors is known, it is largely unknown whether stem cells optimize their receptiveness to niche signals according to the niche o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f375b37b9bdd105bf60efd1863a63ba
https://doi.org/10.1101/2023.03.23.533814
https://doi.org/10.1101/2023.03.23.533814
Autor:
Laura Hakanpää, Amr Abouelezz, An-Sofie Lenaerts, Seyda Culfa, Michael Algie, Jenny Bärlund, Pekka Katajisto, Harvey T McMahon, Leonardo Almeida-Souza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd327d8e4fcb11b7dc0505460be99985
https://doi.org/10.15252/rc.2023903181
https://doi.org/10.15252/rc.2023903181
Autor:
Helena A. K. Lapatto, Minna Kuusela, Aino Heikkinen, Maheswary Muniandy, Birgitta W. van der Kolk, Swetha Gopalakrishnan, Noora Pöllänen, Martin Sandvik, Mark S. Schmidt, Sini Heinonen, Sina Saari, Juho Kuula, Antti Hakkarainen, Janne Tampio, Tuure Saarinen, Marja-Riitta Taskinen, Nina Lundbom, Per-Henrik Groop, Marja Tiirola, Pekka Katajisto, Marko Lehtonen, Charles Brenner, Jaakko Kaprio, Satu Pekkala, Miina Ollikainen, Kirsi H. Pietiläinen, Eija Pirinen
Publikováno v:
Science Advances. 9
Nicotinamide adenine dinucleotide (NAD + ) precursor nicotinamide riboside (NR) has emerged as a promising compound to improve obesity-associated mitochondrial dysfunction and metabolic syndrome in mice. However, most short-term clinical trials condu