Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Pekka Anttila"'
Autor:
Raija Silvennoinen, Anu Partanen, Anders Waage, Valdas Pečeliūnas, Fredrik Schjesvold, Pekka Anttila, Katarina Uttervall, Marjaana Säily, Mervi Putkonen, Kristina Carlson, Einar Haukas, Marja Sankelo, Damian Szatkowski, Markus Hansson, Anu Marttila, Per Axelsson, Ronald Svensson, Birgitta Lauri, Maija Mikkola, Conny Karlsson, Johanna Abelsson, Erik Ahlstrand, Anu Sikiö, Monika Klimkowska, Reda Matuzeviciene, Mona Hoyseter Fenstad, Sorella Ilveskero, Hareth Nahi
Publikováno v:
HemaSphere, Vol 7, p e5534069 (2023)
Externí odkaz:
https://doaj.org/article/d72831d2759849ac8fefd808f7e030d6
Autor:
Marja Hakkarainen, Jessica R. Koski, Caroline A. Heckman, Pekka Anttila, Raija Silvennoinen, Juha Lievonen, Outi Kilpivaara, Ulla Wartiovaara‐Kautto
Publikováno v:
eJHaem, Vol 3, Iss 4, Pp 1352-1357 (2022)
Abstract Observations of inherited susceptibility to multiple myeloma have led to active research in defining predisposing genes to the disease. Here, we analysed 128 plasma cell dyscrasia patients’ germline whole‐exome sequencing data. Rare domi
Externí odkaz:
https://doaj.org/article/2c12cac227bf47e280d6d74f3b53ad94
Autor:
Ciara Tierney, Despina Bazou, Muntasir M. Majumder, Pekka Anttila, Raija Silvennoinen, Caroline A. Heckman, Paul Dowling, Peter O’Gorman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract With the introduction of novel therapeutic agents, survival in Multiple Myeloma (MM) has increased in recent years. However, drug-resistant clones inevitably arise and lead to disease progression and death. The current International Myeloma
Externí odkaz:
https://doaj.org/article/108cd3dd8b6c4ba986fd1fc4eda995a5
Autor:
Minxia Liu, Yinyin Wang, Juho J. Miettinen, Romika Kumari, Muntasir Mamun Majumder, Ciara Tierney, Despina Bazou, Alun Parsons, Minna Suvela, Juha Lievonen, Raija Silvennoinen, Pekka Anttila, Paul Dowling, Peter O’Gorman, Jing Tang, Caroline A. Heckman
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Despite several new therapeutic options, multiple myeloma (MM) patients experience multiple relapses and inevitably become refractory to treatment. Insights into drug resistance mechanisms may lead to the development of novel treatment strategies. Th
Externí odkaz:
https://doaj.org/article/ebd1a0e2671e4755b6242ea4919a4c67
Autor:
Rubén Sánchez-Gómez, Carlos Romero-Morales, Álvaro Gómez-Carrión, Blanca De-la-Cruz-Torres, Ignacio Zaragoza-García, Pekka Anttila, Matti Kantola, Ismael Ortuño-Soriano
Publikováno v:
Sensors, Vol 20, Iss 11, p 3205 (2020)
Background: The mobility of the first metatarsophalangeal joint (I MPTJ) has been related to the proper windlass mechanism and the triceps surae during the heel-off phase of running gait; the orthopedic treatment of the I MPTJ restriction has been ma
Externí odkaz:
https://doaj.org/article/e47987e759ac493d95f11bf1c523a10a
Autor:
Kari Remes, Pekka Anttila, Raija Silvennoinen, Mervi Putkonen, Hanna Ollikainen, Venla Terävä, Marjatta Sinisalo, Kristiina Kananen, Frida Schain, Päivi Castren-Kortegangas, Tiina M Järvinen, Marta Pisini, Felix Wahl, Tricia Dixon, Amy Leval
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208507 (2018)
Outcomes for patients with multiple myeloma (MM) have improved with the advent of novel therapies, however, real-world evidence of outcomes in clinical practice is scarce. We conducted a multi-center registry study to build a reliable picture of trea
Externí odkaz:
https://doaj.org/article/11689cf4afe845ac9bd414f022a2ebe9
Autor:
Iiro Toppila, Kai Kysenius, Tatu Miettinen, Mariann Ida Lassenius, Juha Lievonen, Pekka Anttila
Multiple myeloma (MM) patients are predominantly elderly with comorbidities that have an impact on patient mortality and treatment decisions. We previously reported the patient characteristics and overall survival outcomes of the Finnish MM cohort di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f91af0228ab83f34dc8d374e732fdffb
http://hdl.handle.net/10138/349901
http://hdl.handle.net/10138/349901
Autor:
Sini Luoma, Philipp Sergeev, Komal Kumar Javarappa, Tiina J. Öhman, Markku Varjosalo, Marjaana Säily, Pekka Anttila, Marja Sankelo, Anu Partanen, Anne Nihtinen, Caroline A. Heckman, Raija Silvennoinen
Publikováno v:
Cancers; Volume 15; Issue 9; Pages: 2604
The bone marrow microenvironment interacts with malignant cells and regulates cancer survival and immune evasion in multiple myeloma (MM). We investigated the immune profiles of longitudinal bone marrow samples from patients with newly diagnosed MM (
Autor:
Juha Lievonen, Tatu Miettinen, Mariann I. Lassenius, Pekka Anttila, Melissa Bauer, Iiro Toppila
Publikováno v:
Annals of Hematology. 100:1779-1787
Current understanding of the epidemiology and outcomes for patients with multiple myeloma in Finland is scarce due to lack of comprehensive real-world evidence in clinical practice. The aim of this study was to gain understanding of epidemiological c
Autor:
Muntasir Mamun Majumder, Romika Kumari, Nina N. Nupponen, Raija Silvennoinen, Pekka Anttila, Juha Lievonen, Fredrik Lehmann, Caroline A. Heckman
Publikováno v:
British Journal of Cancer
Background Esterase enzymes differ in substrate specificity and biological function and may display dysregulated expression in cancer. This study evaluated the biological significance of esterase expression in multiple myeloma (MM). Methods For gene