Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Pek Y. Lum"'
Autor:
Eric E. Schadt, Pek Y. Lum
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 12, Pp 2601-2613 (2006)
Diseases such as obesity, diabetes, and atherosclerosis result from multiple genetic and environmental factors, and importantly, interactions between genetic and environmental factors. Identifying susceptibility genes for these diseases using genetic
Externí odkaz:
https://doaj.org/article/2073523c4b4846128544b73772364459
Autor:
ABASIOFIOK MARK IBEKWE, Jincai eMa, David E Crowley, Ching-Hong eYang, Alexis M. Johnson, Tanya C. Petrossian, Pek Y. Lum
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 4 (2014)
Shiga toxin-producing E. coli O157:H7 and non-O157 have been implicated in many foodborne illnesses caused by the consumption of contaminated fresh produce. However, data on their persistence in soils are limited due to the complexity in datasets gen
Externí odkaz:
https://doaj.org/article/db1a105a2f594138b9e5e128fe30c7a2
Autor:
Albert C. Koong, Maho Niwa, Quynh-Thu Le, Amato J. Giaccia, Nicholas C. Denko, Pek Y. Lum, David E. Solow-Cordero, Margaret M. Kozak, Aparna Gupta, Michael P. Hay, Muthuraman Alagappan, Arvin B. Tam, Dadi Jiang
The Supplementary Material contains additional characterization for the compounds mentioned in the paper. We have provided melting point, 1H NMR and low resolution mass spectrometry data as well as HPLC purity for these known compounds. We have also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36a22946057ba1e4e044375218054437
https://doi.org/10.1158/1535-7163.22503138.v1
https://doi.org/10.1158/1535-7163.22503138.v1
Autor:
Jessica L Nielson, Shelly R Cooper, John K Yue, Marco D Sorani, Tomoo Inoue, Esther L Yuh, Pratik Mukherjee, Tanya C Petrossian, Jesse Paquette, Pek Y Lum, Gunnar E Carlsson, Mary J Vassar, Hester F Lingsma, Wayne A Gordon, Alex B Valadka, David O Okonkwo, Geoffrey T Manley, Adam R Ferguson, TRACK-TBI Investigators
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0169490 (2017)
BACKGROUND:Traumatic brain injury (TBI) is a complex disorder that is traditionally stratified based on clinical signs and symptoms. Recent imaging and molecular biomarker innovations provide unprecedented opportunities for improved TBI precision med
Externí odkaz:
https://doaj.org/article/957f8e379b09490ea552d3058dddc116
Autor:
Xudong, Dai, Yudong D, He, Hongyue, Dai, Pek Y, Lum, Christopher J, Roberts, Jeffrey F, Waring, Roger G, Ulrich
Publikováno v:
Genome informatics. International Conference on Genome Informatics. 17(2)
Toxicity is a major cause of failure in drug development. A toxicogenomic approach may provide a powerful tool for better assessing the potential toxicity of drug candidates. Several approaches have been reported for predicting hepatotoxicity based o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::112c08d4090fc361cc718f70b2244f74
https://pubmed.ncbi.nlm.nih.gov/17503381
https://pubmed.ncbi.nlm.nih.gov/17503381
Autor:
Zhidong Tu, Mark P Keller, Chunsheng Zhang, Mary E Rabaglia, Danielle M Greenawalt, Xia Yang, I-Ming Wang, Hongyue Dai, Matthew D Bruss, Pek Y Lum, Yun-Ping Zhou, Daniel M Kemp, Christina Kendziorski, Brian S Yandell, Alan D Attie, Eric E Schadt, Jun Zhu
Publikováno v:
PLoS Genetics, Vol 8, Iss 12, p e1003107 (2012)
Complex diseases result from molecular changes induced by multiple genetic factors and the environment. To derive a systems view of how genetic loci interact in the context of tissue-specific molecular networks, we constructed an F2 intercross compri
Externí odkaz:
https://doaj.org/article/0e466adc0d29468ab383a6fed2c47c6b
Autor:
Eric E Schadt, Cliona Molony, Eugene Chudin, Ke Hao, Xia Yang, Pek Y Lum, Andrew Kasarskis, Bin Zhang, Susanna Wang, Christine Suver, Jun Zhu, Joshua Millstein, Solveig Sieberts, John Lamb, Debraj GuhaThakurta, Jonathan Derry, John D Storey, Iliana Avila-Campillo, Mark J Kruger, Jason M Johnson, Carol A Rohl, Atila van Nas, Margarete Mehrabian, Thomas A Drake, Aldons J Lusis, Ryan C Smith, F Peter Guengerich, Stephen C Strom, Erin Schuetz, Thomas H Rushmore, Roger Ulrich
Publikováno v:
PLoS Biology, Vol 6, Iss 5, p e107 (2008)
Genetic variants that are associated with common human diseases do not lead directly to disease, but instead act on intermediate, molecular phenotypes that in turn induce changes in higher-order disease traits. Therefore, identifying the molecular ph
Externí odkaz:
https://doaj.org/article/690823c1095b471bb00d96bfa2f8780e
Autor:
Jun Zhu, Matthew C Wiener, Chunsheng Zhang, Arthur Fridman, Eric Minch, Pek Y Lum, Jeffrey R Sachs, Eric E Schadt
Publikováno v:
PLoS Computational Biology, Vol 3, Iss 4, p e69 (2007)
To dissect common human diseases such as obesity and diabetes, a systematic approach is needed to study how genes interact with one another, and with genetic and environmental factors, to determine clinical end points or disease phenotypes. Bayesian
Externí odkaz:
https://doaj.org/article/4e13b757b79a4a65a0ed64bea730fc66