Výsledky vyhledávání - "Pejnović, Lana"

Akademický článek

Farmakogenetika u kliničkoj praksi - preporuke i smjernice Smjernice za kliničku praksu.

Autor: Božina, Nada nbozina@kbc-zagreb.hr, Pejnović, Lana¹

Publikováno v: Paediatria Croatica. Oct2013, Vol. 57 Issue 4, p318-330. 13p.

Influence of CYP2D6 and ABCB1 polimorphisms on the serum steady-state concentrations of risperidone and 9-oh risperidone in patients using long-acting injectable risperidone

Autor: Pejnović, Lana, Božina, Nada, Lovrić, Mila, Živković, Maja, Klarica, Iva, Filipčić, Igor

INTRODUCTION: An increased risk of adverse effects and discontinuation of risperidone therapy is observed in patients with schizophrenia. Long- acting injectable (LAI) risperidone should have improved pharmacokinetics and reduce side effects. Risperi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2112782cda6ce23d842ff064e43a4f5b
https://www.bib.irb.hr/811182

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Acute extrapyramidal adverse effects in male schizophrenic patients treated with haloperidol: the association study of polymorphisms in DRD2, SLC6A3, and COMT genes

Autor: Živković, Maja, Mihaljević-Peleš, Alma, Božina, Nada, Šagud, Marina, Brečić, Petrana, Bagarić, Dario, Pejnović, Lana, Vuksan-Cusa, Bjanka, Nikolac Perković, Matea, Muck-Šeler, Dorotea

Objective: Several gene polymorphisms may be important in potential to antipsychotic-induced acute extrapyramidal adverse effects (EPS) in schizophrenia. The goal of this study was to determine association between dopaminergic type 2 receptor (DRD2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::0c1bed3c3b90555857ae24da0e649229
https://www.bib.irb.hr/811187

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Lethal toxicity following standard dose of 5-FU in patients carrying DPYD c.1905+1G>A mutation

Autor: Božina, Nada, Goršić, Irma, Pejnović, Lana, Badžek, Saša, Pleština, Stjepko

Dihydropyrimidine dehydrogenase (DPD) is the key enzyme in the detoxification of 5-fluorouracil (5-FU). Patients with DPD deficiency are at increased risk of severe toxicity from 5-FU. UGT1A1 is important for the irinotecan pharmacokinetic. DPYD c.19

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::a11ea9e9633354a66af2dd6b501bc2fc
https://www.bib.irb.hr/686002

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Farmakogenetika u kliničkoj praksi – preporuke i smjernice

Autor: Božina, Nada, Pejnović, Lana

Varijabilnosti u učinku lijeka mogu se djelomično objasniti genetičkim razlikama. Postoje interindividualne razlike u metaboličkom i transportnom kapacitetu i detoksikaciji lijekova i drugih ksenobiotika. Osjetljivost na toksične učinke jednim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::1a54ce090f05541f7cf0de3be1ebda91
https://www.bib.irb.hr/683487

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The association study of polymorphisms DRD2, SLC6A3 and COMT genes and achieving the symptomatic remission in male schizophrenic patients treated with olanzapine

Autor: Živković, Maja, Mihaljević-Peleš, Alma, Muck- Šeler, Dorotea, Šagud, Marina, Pivac, Nela, Pejnović, Lana, Božina, Nada

INTRODUCTION: Olanzapine is one of the most prescribed second generation antipsychotic used in the treatment of schizophrenia. Along with other factors, variations in treatment response among patients with schizophrenia could be genetically predeterm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::2854f8ebd350d2d3346d9c9c52d84c1f
https://www.bib.irb.hr/666274

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Drug transporter and metabolic enzyme gene variants and fluvastatin adverse drug reactions in renal transplant recipients

Autor: Mirošević Skvrce, Nikica, Božina, Nada, Božina, Tamara, Barišić, Ivan, Zibar, Lada, Pejnović, Lana, Macolić-Šarinić, Viola

BACKGROUND. Statin use in transplant recipients had been hindered by concern about adverse drug reactions (ADRs). Polymorphisms in genes encoding metabolic enzymes and drug transporters could be valuable predictors of fluvastatin ADRs. Fluvastatin is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::4668ce6249d1585881438d4ce0ae0844
https://www.bib.irb.hr/965867

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Uloga polimorfizma prijenosnika lijekova u kliničkoj praksi ; put prema personaliziranom liječenju

Autor: Božina, Nada, Lovrić, Mila, Pejnović, Lana, Mirošević Skvrce, Nikica

Drug transporters play important role in carrying their substrates accross different barriers, and are an important factor of drug bioavailability. They can act as uptake or efflux transporters. Most efflux transporters belong to the ATP-binding cass

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::fb41fc2783d200edc141cd7b43ebeb5e
https://www.bib.irb.hr/680564

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Nove farmakogenetičke smjernice u kliničkoj praksi

Autor: Božina, Nada, Pejnović, Lana

Važnost znanstvenih istraživanja u području farmakogenetike i njihov uspješan prijenos u kliničku praksu: enzimi uključeni u metabolizam lijekova još uvijek u središtu farmakogenetičkih studija. Primjerice, ustanovljeno je da polimorfi zam e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::d26a8c6c847e454065356e69c524816e
https://www.bib.irb.hr/685921

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