Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Peixin Amy Chen"'
Autor:
Linda T. Vo, P. Jonathan Li, Theodore L. Roth, Murad R. Mamedov, David N. Nguyen, Peixin Amy Chen, Eric Shifrut, Jeffrey A. Bluestone, Ryan Apathy, Alexander Marson, Francis C. Szoka, Jennifer M. Puck, Daniel B. Goodman, Victoria Tobin
Publikováno v:
Nature biotechnology
Nature biotechnology, vol 38, iss 1
Nature biotechnology, vol 38, iss 1
Versatile and precise genome modifications are needed to create a wider range of adoptive cellular therapies1-5. Here we report two improvements that increase the efficiency of CRISPR-Cas9-based genome editing in clinically relevant primary cell type
Autor:
Natasha L. Rudy, Anna C.E. Hurst, Alexander Marson, Steven H. Kroft, James Garifallou, Sarah K. Nicholas, Piyush Pillarisetti, Gerald Wertheim, Di Sun, Andrew D. Wells, Titus J. Boggon, Gregory M.K. Poon, Kelly Maurer, Brian Nolan, Caroline Khanna, Francis Wright, Jennifer M. Puck, Struan F.A. Grant, Suela Xhani, Amy Rymaszewski, Ivan K. Chinn, Viktoria Zakharova, Samuel Yoon, James W. Verbsky, Neil Romberg, David N. Nguyen, Linda T. Vo, Kathleen E. Sullivan, Chun Su, Anna Shcherbina, Alix E. Seif, T. Prescott Atkinson, Amy L. Stiegler, Hakon Hakonarson, Anna Mukhina, Amanda V. Albrecht, Timothy S. Olson, Peixin Amy Chen, John M. Routes, Benjamin Demaree, Joud Hajjar, James R. Lupski, Adam R. Abate, Michael Gonzalez, Carole Le Coz
Publikováno v:
Journal of Experimental Medicine. 218
The pioneer transcription factor (TF) PU.1 controls hematopoietic cell fate by decompacting stem cell heterochromatin and allowing nonpioneer TFs to enter otherwise inaccessible genomic sites. PU.1 deficiency fatally arrests lymphopoiesis and myelopo
Autor:
Murad R Mamedov, Shane Vedova, Jacob W. Freimer, Avinash Das Sahu, Peixin Amy Chen, Amrita Ramesh, Kristina Hanspers, Vinh Q. Nguyen, Erin J Adams, Alexander Marson
Publikováno v:
The Journal of Immunology. 208:62.10-62.10
γδ T cells are potent anti-cancer effectors with potential to target tumors broadly, independent of neoantigens or HLA-background. γδ T cells can sense conserved cell stress signals prevalent in transformed cells, although the mechanisms governin
Autor:
Theodore L. Roth, Francis C. Szoka, Eric Shifrut, Jeffrey A. Bluestone, Puck Jm, Murad R. Mamedov, Peixin Amy Chen, Jia Jie Li, David N. Nguyen, Ryan Apathy, Alexander Marson, Tobin, Daniel B. Goodman, Linda T. Vo
Virus-modified T cells are approved for cancer immunotherapy, but more versatile and precise genome modifications are needed for a wider range of adoptive cellular therapies1–4. We recently developed a non-viral CRISPR–Cas9 system for genomic sit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e256adbe001873bc098df8a6e71f5b
https://doi.org/10.1101/591719
https://doi.org/10.1101/591719