Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Peiwen Pan"'
Autor:
Ashok Aspatwar, Martti E E Tolvanen, Markus J T Ojanen, Harlan R Barker, Anni K Saralahti, Carina A Bäuerlein, Csaba Ortutay, Peiwen Pan, Marianne Kuuslahti, Mataleena Parikka, Mika Rämet, Seppo Parkkila
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134263 (2015)
Carbonic anhydrase related proteins (CARPs) X and XI are highly conserved across species and are predominantly expressed in neural tissues. The biological role of these proteins is still an enigma. Ray-finned fish have lost the CA11 gene, but instead
Externí odkaz:
https://doaj.org/article/bf2bdb2046b64c29b17a23b9c484d97c
Autor:
Sina Saari, Mika Hilvo, Peiwen Pan, Gerolf Gros, Nina Hanke, Abdul Waheed, William S Sly, Seppo Parkkila
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9624 (2010)
BACKGROUND: Carbonic anhydrases (CAs) are key enzymes for physiological pH regulation, including the process of urine acidification. Previous studies have identified seven cytosolic or membrane-bound CA isozymes in the kidney. Recently, we showed by
Externí odkaz:
https://doaj.org/article/1f23071e662a4ca4aabfd630d24f440f
Publikováno v:
Transgenic Research. 25:649-664
From birth, the respiratory tract mucosa is exposed to various chemical, physical, and microbiological stress factors. Efficient defense mechanisms and strictly regulated renewal systems in the mucosa are thus required. Carbonic anhydrase VI (CA VI)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2da8db2a701fd503b7a5cd8e4bb24cd4
https://doi.org/10.1007/s11248-016-9961-5
https://doi.org/10.1007/s11248-016-9961-5
Publikováno v:
ACIT
With the development of modern society. The unprecedented prosperity of science & technology and finance. Objects formed a huge amount of track data in its movement. The large amount of track data contains rich spatio-temporal characteristics informa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb9653212a8276fd1838e7775d827704
https://doi.org/10.1145/3265007.3265015
https://doi.org/10.1145/3265007.3265015
Autor:
Peiwen Pan, Giuseppe La Regina, Elisa Nuti, Ludovica Monti, Vincenzo Alterio, Antonio Coluccia, Sveva Pelliccia, Claudiu T. Supuran, Romano Silvestri, Seppo Parkkila, Simona Maria Monti, Valeria Famiglini, Giuseppina De Simone, Armando Rossello, Daniela Vullo
Publikováno v:
Journal of Medicinal Chemistry. 58:8564-8572
New 1,1'-biphenylsulfonamides were synthesized and evaluated as inhibitors of the ubiquitous human carbonic anhydrase isoforms I, II, IX, XII, and XIV using acetazolamide (AAZ) as reference compound. The sulfonamides 1-21 inhibited all the isoforms,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f12cc46794e8674b63826b578a8e6186
https://doi.org/10.1021/acs.jmedchem.5b01144
https://doi.org/10.1021/acs.jmedchem.5b01144
The role of carbonic anhydrase VI in bitter taste perception: evidence from the Car6-/- mouse model.
Autor:
Patrikainen, Maarit1 maarit.patrikainen@uta.fi, Peiwen Pan1 peiwenpan612@gmail.com, Kulesskaya, Natalia2 natalia.kulesskaya@helsinki.fi, Voikar, Vootele2 vootele.voikar@helsinki.fi, Parkkila, Seppo1,3 seppo.parkkila@uta.fi
Publikováno v:
Journal of Biomedical Science. 2014, Vol. 21 Issue 1, p1-14. 14p. 2 Color Photographs, 1 Graph.
Publikováno v:
The Journal of organic chemistry. 82(3)
A practical and efficient method for divergent synthesis of 3,6-disubstituted- and 3,5,6-trisubstituted-1,2,4-triazines via unexpected rhodium-catalyzed O–H insertion/rearrangement/conditions-controlled intramolecular cyclization and oxidation reac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49223303dfa9f306b9a6ee70e80495a2
https://pubmed.ncbi.nlm.nih.gov/28094530
https://pubmed.ncbi.nlm.nih.gov/28094530
Autor:
Hannele Uusitalo-Järvinen, Abdul Waheed, Silvia Pastorekova, Maria Vähätupa, Seppo Parkkila, William S. Sly, Peiwen Pan, Marleena Aaltonen, Pirkka Kaipiainen, Harlan Barker, Stuart Prince, Ulrike May, Tero A. H. Järvinen
Publikováno v:
Experimental & Molecular Medicine
Skin wound closure occurs when keratinocytes migrate from the edge of the wound and re-epithelialize the epidermis. Their migration takes place primarily before any vascularization is established, that is, under hypoxia, but relatively little is know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26cc4119b202afc3b2d704826aa4e807
https://trepo.tuni.fi/handle/10024/101957
https://trepo.tuni.fi/handle/10024/101957
Autor:
Claudiu T. Supuran, Vincenzo Alterio, Martina Buonanno, Simona Maria Monti, Peiwen Pan, Seppo Parkkila, Giuseppina De Simone
Publikováno v:
Biopolymers. 101:769-778
Carbonic anhydrase isoform XIV (CA XIV) is the last member of the human (h) CA family discovered so far, being localized in brain, kidneys, colon, small intestine, urinary bladder, liver, and spinal cord. It has recently been described as a possible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5083fdd6e609e1345ef6310af62788fa
https://doi.org/10.1002/bip.22456
https://doi.org/10.1002/bip.22456
Autor:
Claudiu T. Supuran, Alane Beatriz Vermelho, Seppo Parkkila, Andrea Scozzafava, Peiwen Pan, Clemente Capasso
Publikováno v:
Bioorganic & Medicinal Chemistry. 21:4472-4476
The protozoan pathogen Trypanosoma cruzi, the causative agent of Chagas disease, encodes an α-class carbonic anhydrase (CA, EC 4.2.1.1), TcCA, which was recently shown to be crucial for its life cycle. Thiols, a class of strong TcCA inhibitors, were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::609adcee94a385562cbec41cf330772b
https://doi.org/10.1016/j.bmc.2013.05.058
https://doi.org/10.1016/j.bmc.2013.05.058