Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Peiwen Fan"'
Publikováno v:
Translational Oncology, Vol 44, Iss , Pp 101923- (2024)
Objective: This study aimed to investigate the genomic alteration profiles of cervical cancer patients, examine the correlation between mutation patterns and clinical and immune attributes, and discover novel targets for treatment of individuals with
Externí odkaz:
https://doaj.org/article/3c48774c891c478095de26222c699246
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundThe combination of agonistic antibodies with immune checkpoint inhibitors presents a promising avenue for cancer immunotherapy. Our objective is to explore the co-expression of 4-1BB, ICOS, CD28, with PD-1 on CD8+ T cells in the peripheral
Externí odkaz:
https://doaj.org/article/91fc37f17fe448c3b07e2ed6177218bb
Publikováno v:
Biomolecules & Biomedicine, Vol 23, Iss 4 (2023)
The use of immune checkpoint inhibitors in malignant tumors improves patient outcomes. Because single-agent immune checkpoint blockade has a low objective response rate, it is meaningful to explore combined blockade of immune checkpoint receptors. We
Externí odkaz:
https://doaj.org/article/d964facf99334fbf83119c87b2c606e7
Publikováno v:
Heliyon, Vol 9, Iss 5, Pp e16079- (2023)
Object: This study sought to elucidate the role of microRNA-210 (miR-210) in the occurrence and development of lung adenocarcinoma (LUAD). Methods: The levels of lncRNA miR-210HG and miR-210 in LUAD tissues and corresponding normal tissues were analy
Externí odkaz:
https://doaj.org/article/0a39a429e19a4d23bffb34d9d3e05c7b
Publikováno v:
Precision Radiation Oncology, Vol 6, Iss 3, Pp 199-208 (2022)
Abstract Objective We aimed to investigate the relationship between the expression of killer cell lectin like receptor G1 (KLRG1) in peripheral blood lymphocytes, and the clinical characteristics and prognosis in patients with locally advanced nasoph
Externí odkaz:
https://doaj.org/article/af1d8d11d1084454840c631b9a2da56c
Autor:
Yong-Qiao He, Tong-Min Wang, Mingfang Ji, Zhi-Ming Mai, Minzhong Tang, Ruozheng Wang, Yifeng Zhou, Yuming Zheng, Ruowen Xiao, Dawei Yang, Ziyi Wu, Changmi Deng, Jiangbo Zhang, Wenqiong Xue, Siqi Dong, Jiyun Zhan, Yonglin Cai, Fugui Li, Biaohua Wu, Ying Liao, Ting Zhou, Meiqi Zheng, Yijing Jia, Danhua Li, Lianjing Cao, Leilei Yuan, Wenli Zhang, Luting Luo, Xiating Tong, Yanxia Wu, Xizhao Li, Peifen Zhang, Xiaohui Zheng, Shaodan Zhang, Yezhu Hu, Weiling Qin, Bisen Deng, Xuejun Liang, Peiwen Fan, Yaning Feng, Jia Song, Shang-Hang Xie, Ellen T. Chang, Zhe Zhang, Guangwu Huang, Miao Xu, Lin Feng, Guangfu Jin, Jinxin Bei, Sumei Cao, Qing Liu, Zisis Kozlakidis, Haiqiang Mai, Ying Sun, Jun Ma, Zhibin Hu, Jianjun Liu, Maria Li Lung, Hans-Olov Adami, Hongbing Shen, Weimin Ye, Tai-Hing Lam, Yi-Xin Zeng, Wei-Hua Jia
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Polygenic Risk Scores (PRS) show promise for facilitating cancer risk stratification. Here, the authors performed a large genome-wide association study and develop a PRS for nasopharyngeal carcinoma, which could improve risk stratification and person
Externí odkaz:
https://doaj.org/article/38540eac80b54048956f4f90b04a69b8
Autor:
Hongchao Cai, Yaning Feng, Peiwen Fan, Yuping Guo, Gulina Kuerban, Cheng Chang, Xuan Yao, Yanchun Peng, Ruozheng Wang
Publikováno v:
Infectious Agents and Cancer, Vol 16, Iss 1, Pp 1-11 (2021)
Abstract Background T cell epitopes are polypeptide fragments presented to T cell receptors by MHC molecules encoded by human leukocyte antigen (HLA) genes after antigen-presenting cell processing, which is the basis for the study of antigen immune m
Externí odkaz:
https://doaj.org/article/e58ee5ebe51548b599111e08dfaad40e
Autor:
Peiwen Fan, Xi Li, Yaning Feng, Hongchao Cai, Danning Dong, Yanchun Peng, Xuan Yao, Yuping Guo, Miaomiao Ma, Tao Dong, Ruozheng Wang
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Despite the expansion of PD-1 checkpoint blockade to multiple types of cancer, whether the programmed cell death 1 (PD-1) expression status on CD8+ tumour infiltrating lymphocytes (TILs) could be a prognostic factor in cervical cancer is still unclea
Externí odkaz:
https://doaj.org/article/31b20a1059c148e1aa7fdec330d9f045
Publikováno v:
Infectious Agents and Cancer, Vol 13, Iss 1, Pp 1-9 (2018)
Abstract Background Cervical cancer is attributable to human papilloma virus (HPV) infection in the majority cases. E1, an HPV derived-protein, plays an important role in the initiation and development of cervical cancer. Our study aims to investigat
Externí odkaz:
https://doaj.org/article/ae777060f0ee4acdb1ae17ccb098809d
Autor:
Xi Li, Rouzheng Wang, Peiwen Fan, Xuan Yao, Ling Qin, Yanchun Peng, Miaomiao Ma, Neil Asley, Xuimei Chang, Yaning Feng, Yunhui Hu, Yonghong Zhang, Chris Li, Gregory Fanning, Stephanie Jones, Clare Verrill, David Maldonado-Perez, Paul Sopp, Craig Waugh, Stephen Taylor, Simon Mcgowan, Vincenzo Cerundolo, Christopher Conlon, Andrew McMichael, Shichun Lu, Xiyan Wang, Ning Li, Tao Dong
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Background: Cancer patients often display dysfunctional antitumor T-cell responses. Because noteworthy benefits of immune checkpoint pathway blockade, such as programmed cell death protein 1 (PD-1) inhibitors, have been achieved in multiple advanced
Externí odkaz:
https://doaj.org/article/772c0dafccf74a729e4b3727ac88843d