Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Peirong Yang"'
Autor:
Yun Zhang, Shunbin Xiong, Bin Liu, Vinod Pant, Francis Celii, Gilda Chau, Ana C. Elizondo-Fraire, Peirong Yang, Mingjian James You, Adel K. El-Naggar, Nicholas E. Navin, Guillermina Lozano
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Mutations in TP53 gene are very common in cancer development. Here the authors take advantage of murine models to show that somatic Trp53 mutations differentially drive breast cancer and evolution of metastases.
Externí odkaz:
https://doaj.org/article/6f7368c1d73241eeac39f0f8b051d0b9
Autor:
Zhaojing Zheng, Li Hong, Xiaodong Huang, Peirong Yang, Juan Li, Yu Ding, Ru-En Yao, Juan Geng, Yongnian Shen, Yiping Shen, Qihua Fu, Yongguo Yu
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67039 (2013)
To investigate potential functional variants in FTO and SH2B1 genes among Chinese children with obesity.Sanger sequencing of PCR products of all FTO and SH2B1 exons and their flanking regions were performed in 338 Chinese Han children with obesity an
Externí odkaz:
https://doaj.org/article/0a483747ef3345fdbf317da661905895
Autor:
Xiaodong Huang, Zhaohui Lu, Zhongwei Lv, Tingting Yu, Peirong Yang, Yongnian Shen, Yu Ding, Da Fu, Xiaoping Zhang, Qihua Fu, Yongguo Yu
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71553 (2013)
Phenylketonuria (PKU), an autosomal recessive disorder of amino acid metabolism caused by mutations in the phenylalanine hydroxylase (PAH) gene, leads to childhood mental retardation by exposing neurons to cytotoxic levels of phenylalanine (Phe). A r
Externí odkaz:
https://doaj.org/article/42d95a12311c4c13886aaaa379008ed1
Autor:
Guillermina Lozano, Gilda Chau, James G. Jackson, Peirong Yang, Shunbin Xiong, Adel K. El-Naggar, Yun Zhang, Qin Li
The p53 (TP53) tumor suppressor is the most frequently mutated gene in human cancers. Restoring expression of wild-type p53 has led to tumor growth suppression in a variety of tumor models that are p53 deficient. Other mechanisms, for example, upregu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::553e74add2e0d52bc76ae4234b7fdb27
https://doi.org/10.1158/1541-7786.c.6540082.v1
https://doi.org/10.1158/1541-7786.c.6540082.v1
Autor:
Guillermina Lozano, Gilda Chau, James G. Jackson, Peirong Yang, Shunbin Xiong, Adel K. El-Naggar, Yun Zhang, Qin Li
PDF file - 354K, Figure S1. Tumor-free survival curves of the Mdm2Tg p53Neo/Neo and Mdm2Tg p53Neo/Neo CreER mice. Figure S2. Analysis of p53Neo recombination in tamoxifen-treated Mdm2Tg p53Neo/Neo CreER tumors. Figure S3. Initial tumor volumes of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98bae288f35b5bbabe8f1eca66cc52b6
https://doi.org/10.1158/1541-7786.22511944.v1
https://doi.org/10.1158/1541-7786.22511944.v1
Autor:
Shunbin Xiong, Dhruv Chachad, Yun Zhang, Jovanka Gencel-Augusto, Mario Sirito, Vinod Pant, Peirong Yang, Chang Sun, Gilda Chau, Yuan Qi, Xiaoping Su, Elizabeth M. Whitley, Adel K. El-Naggar, Guillermina Lozano
Publikováno v:
Cancer Res
The majority of TP53 missense mutations identified in cancer patients are in the DNA-binding domain and are characterized as either structural or contact mutations. These missense mutations exhibit inhibitory effects on wild-type p53 activity. More i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c9eb6ec46b920498654f867fda44067
https://doi.org/10.1158/0008-5472.can-21-3376
https://doi.org/10.1158/0008-5472.can-21-3376
Autor:
Guillermina Lozano, Adel K. El-Naggar, Elizabeth M. Whitley, Xiaoping Su, Yuan Qi, Gilda Chau, Chang Sun, Peirong Yang, Vinod Pant, Mario Sirito, Jovanka Gencel-Augusto, Yun Zhang, Dhruv Chachad, Shunbin Xiong
Supplementary Data from Differential Gain-of-Function Activity of Three p53 Hotspot Mutants In Vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f61202988b4872111a72a07e59b8ed
https://doi.org/10.1158/0008-5472.22430796.v1
https://doi.org/10.1158/0008-5472.22430796.v1
Autor:
Guillermina Lozano, Adel K. El-Naggar, Elizabeth M. Whitley, Xiaoping Su, Yuan Qi, Gilda Chau, Chang Sun, Peirong Yang, Vinod Pant, Mario Sirito, Jovanka Gencel-Augusto, Yun Zhang, Dhruv Chachad, Shunbin Xiong
The majority of TP53 missense mutations identified in cancer patients are in the DNA-binding domain and are characterized as either structural or contact mutations. These missense mutations exhibit inhibitory effects on wild-type p53 activity. More i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a67c92d56086e8319c53b9da6550756d
https://doi.org/10.1158/0008-5472.c.6513720.v1
https://doi.org/10.1158/0008-5472.c.6513720.v1
Autor:
Shunbin Xiong, Dhruv Chachad, Yun Zhang, Jovanka Gencel-Augusto, Mario Sirito, Vinod Pant, Peirong Yang, Chang Sun, Guillermina Lozano
Publikováno v:
Cancer Research. 83:A042-A042
The majority of p53 missense mutations identified in cancer patients are in the DNA-binding domain and are characterized as either structural or contact mutations. These missense mutations exhibit inhibitory effects on wild-type p53 activity. More im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b82c2d8df64e3a18d82d610be08d4c8b
https://doi.org/10.1158/1538-7445.metastasis22-a042
https://doi.org/10.1158/1538-7445.metastasis22-a042
Publikováno v:
International Journal of Chronic Diseases, Vol 2021 (2021)
International Journal of Chronic Diseases
International Journal of Chronic Diseases
Background. Overweight and obesity have become a serious health problem. There are a few data on the prevalence of overweight and obesity in Baoji city of western China, this study was conducted to investigate the epidemiologic features of overweight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c384a302fc9d467e67b3b9699277ee4
https://doaj.org/article/8e34c989b525433da345734f83861235
https://doaj.org/article/8e34c989b525433da345734f83861235