CBA (4-chloro-2-(2-chlorophenoxy)acetamido) benzoic acid) inhibits TMEM206 mediated currents and TMEM206 does not contribute to acid-induced cell death in colorectal cancer cells.

Autor: Kappel S; Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland., Melek K; Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland., Ross-Kaschitza D; Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland., Hauert B; Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland., Gerber CE; Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland., Lochner M; Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland., Peinelt C; Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland.

Publikováno v: Frontiers in pharmacology [Front Pharmacol] 2024 Mar 07; Vol. 15, pp. 1369513. Date of Electronic Publication: 2024 Mar 07 (Print Publication: 2024).

A Simple and Fast Method for the Formation and Downstream Processing of Cancer-Cell-Derived 3D Spheroids: An Example Using Nicotine-Treated A549 Lung Cancer 3D Spheres.

Autor: Papapostolou I; Institute of Biochemistry and Molecular Medicine, University of Bern, 3012 Bern, Switzerland., Bochen F; Institute of Biochemistry and Molecular Medicine, University of Bern, 3012 Bern, Switzerland., Peinelt C; Institute of Biochemistry and Molecular Medicine, University of Bern, 3012 Bern, Switzerland., Maldifassi MC; Institute of Biochemistry and Molecular Medicine, University of Bern, 3012 Bern, Switzerland.

Publikováno v: Methods and protocols [Methods Protoc] 2023 Oct 04; Vol. 6 (5). Date of Electronic Publication: 2023 Oct 04.

Targeting Ion Channel TRPM4.

Autor: Preti B; Institute if Biochemistry and Molecular Medicine, University of Bern., Rougier JS; Institute of Biochemistry and Molecular Medicine, University of Bern., Papapostolou I; Institute of Biochemistry and Molecular Medicine, University of Bern., Bochen F; Institute of Biochemistry and Molecular Medicine, University of Bern., Gerber CE; Institute of Biochemistry and Molecular Medicine, University of Bern., Abriel H; Institute of Biochemistry and Molecular Medicine, University of Bern. hugues.abriel@unibe.ch., Lochner M; Institute of Biochemistry and Molecular Medicine, University of Bern. martin.lochner@unibe.ch., Peinelt C; Institute of Biochemistry and Molecular Medicine, University of Bern. christine.peinelt@ibmm.unibe.ch.

Publikováno v: Chimia [Chimia (Aarau)] 2022 Dec 21; Vol. 76 (12), pp. 1039-1044. Date of Electronic Publication: 2022 Dec 21.

Discovery of novel gating checkpoints in the Orai1 calcium channel by systematic analysis of constitutively active mutants of its paralogs and orthologs.

Autor: Augustynek B; Membrane Transport Discovery Lab, Department of Nephrology and Hypertension and Department of Biomedical Research, Inselspital, University of Bern, Freiburgstrasse 15, CH-3010 Bern, Switzerland., Gyimesi G; Membrane Transport Discovery Lab, Department of Nephrology and Hypertension and Department of Biomedical Research, Inselspital, University of Bern, Freiburgstrasse 15, CH-3010 Bern, Switzerland., Dernič J; Membrane Transport Discovery Lab, Department of Nephrology and Hypertension and Department of Biomedical Research, Inselspital, University of Bern, Freiburgstrasse 15, CH-3010 Bern, Switzerland., Sallinger M; Institute of Biophysics, JKU Life Science Center, Johannes Kepler University Linz, A-4020 Linz, Austria., Albano G; Membrane Transport Discovery Lab, Department of Nephrology and Hypertension and Department of Biomedical Research, Inselspital, University of Bern, Freiburgstrasse 15, CH-3010 Bern, Switzerland., Klesse GJ; Membrane Transport Discovery Lab, Department of Nephrology and Hypertension and Department of Biomedical Research, Inselspital, University of Bern, Freiburgstrasse 15, CH-3010 Bern, Switzerland., Kandasamy P; Membrane Transport Discovery Lab, Department of Nephrology and Hypertension and Department of Biomedical Research, Inselspital, University of Bern, Freiburgstrasse 15, CH-3010 Bern, Switzerland., Grabmayr H; Institute of Biophysics, JKU Life Science Center, Johannes Kepler University Linz, A-4020 Linz, Austria., Frischauf I; Institute of Biophysics, JKU Life Science Center, Johannes Kepler University Linz, A-4020 Linz, Austria., Fuster DG; Membrane Transport Discovery Lab, Department of Nephrology and Hypertension and Department of Biomedical Research, Inselspital, University of Bern, Freiburgstrasse 15, CH-3010 Bern, Switzerland., Peinelt C; Institute of Biochemistry and Molecular Medicine, University of Bern, Bühlstrasse 28, 3012 Bern, Switzerland., Hediger MA; Membrane Transport Discovery Lab, Department of Nephrology and Hypertension and Department of Biomedical Research, Inselspital, University of Bern, Freiburgstrasse 15, CH-3010 Bern, Switzerland. Electronic address: matthias.hediger@ibmm.unibe.ch., Bhardwaj R; Membrane Transport Discovery Lab, Department of Nephrology and Hypertension and Department of Biomedical Research, Inselspital, University of Bern, Freiburgstrasse 15, CH-3010 Bern, Switzerland; Current address: Signal Transduction Laboratory, National Institute of Environmental Health Sciences, NIH, 111 TW Alexander Drive, NC 27709, USA. Electronic address: rajesh.bhardwaj@nih.gov.

Publikováno v: Cell calcium [Cell Calcium] 2022 Jul; Vol. 105, pp. 102616. Date of Electronic Publication: 2022 Jun 22.

A Novel Role of the TRPM4 Ion Channel in Exocytosis.

Autor: Stokłosa P; Institute of Biochemistry and Molecular Medicine, University of Bern, 3012 Bern, Switzerland., Kappel S; Institute of Biochemistry and Molecular Medicine, University of Bern, 3012 Bern, Switzerland., Peinelt C; Institute of Biochemistry and Molecular Medicine, University of Bern, 3012 Bern, Switzerland.

Publikováno v: Cells [Cells] 2022 May 30; Vol. 11 (11). Date of Electronic Publication: 2022 May 30.