Ground Temperature Monitoring and Simulation of Temperature Field Changes in Block-Stone Material Replacement Foundation for the Shiwei–Labudalin Highway

Autor: Wei Shan, Yutong Li, Ying Guo, Chengcheng Zhang, Peijie Hou

Publikováno v: Applied Sciences, Vol 14, Iss 14, p 6222 (2024)

The current thermal balance of permafrost in northeastern China has been upset by human engineering construction disturbances and global warming. This has resulted in a rise in ground temperature and a fall in the permafrost table, which has a major

Externí odkaz: https://doaj.org/article/21ab75ec06e14cd58b0476a79ccab90a

Efficacy and safety of a single dose of casirivimab and imdevimab for the prevention of COVID-19 over an 8-month period: a randomised, double-blind, placebo-controlled trial

Autor: Gary A Herman, Meagan P O'Brien, Eduardo Forleo-Neto, Neena Sarkar, Flonza Isa, Peijie Hou, Kuo-Chen Chan, Katharine J Bar, Ruanne V Barnabas, Dan H Barouch, Myron S Cohen, Christopher B Hurt, Dale R Burwen, Mary A Marovich, Bret J Musser, John D Davis, Kenneth C Turner, Adnan Mahmood, Andrea T Hooper, Jennifer D Hamilton, Janie Parrino, Danise Subramaniam, Alina Baum, Christos A Kyratsous, A Thomas DiCioccio, Neil Stahl, Ned Braunstein, George D Yancopoulos, David M Weinreich, Achint Chani, Adebiyi Adepoju, Aisha Mortagy, Ajla Dupljak, Alison Brown, Amy Froment, Andrea Hooper, Andrea Margiotta, Andrew Bombardier, Anita Islam, Anne Smith, Arvinder Dhillon, Audra McMillian, Aurora Breazna, Ayesha Aslam, Barabara Carpentino, Bari Kowal, Barry Siliverstein, Benjamin Horel, Bo Zhu, Bret Musser, Brian Bush, Brian Head, Brian Snow, Bryan Zhu, Camille Debray, Careta Phillips, Carmella Simiele, Carol Lee, Carolyn Nienstedt, Caryn Trbovic, Casey (Kuo-Chen) Chan, Catherine Elliott, Chad Fish, Charlie Ni, Christa Polidori, Christine Enciso, Christopher Caira, Christopher Powell, Christos A. Kyratsous, Cliff Baum, Colin McDonald, Cynthia Leigh, Cynthia Pan, Dana Wolken, Danielle Manganello, David Liu, David Stein, David M. Weinreich, Dawlat Hassan, Daya Gulabani, Deborah Fix, Deborah Leonard, Deepshree Sarda, Denise Bonhomme, Denise Kennedy, Devin Darcy, Dhanalakshmi Barron, Diana Hughes, Diana Rofail, Dipinder Kaur, Divya Ramesh, Dona Bianco, Donna Cohen, Edward Jean-Baptiste, Ehsan Bukhari, Eileen Doyle, Elizabeth Bucknam, Emily Labriola-Tomkins, Emily Nanna, Esther Huffman O'Keefe, Evelyn Gasparino, Evonne Fung, Fung-Yee To, Gary Herman, George D. Yancopoulos, Georgia Bellingham, Giane Sumner, Grainne Moggan, Grainne Power, Haixia Zeng, Hazel Mariveles, Heath Gonzalez, Helen Kang, Hibo Noor, Ian Minns, Ingeborg Heirman, Izabella Peszek, James Donohue, Jamie Rusconi, Janice Austin, Jeannie Yo, Jenna McDonnell, Jennifer D. Hamilton, Jessica Boarder, Jianguo Wei, Jingchun Yu, Joanne Malia, Joanne Tucciarone, Jodie Tyler-Gale, John D. Davis, John Strein, Jonathan Cohen, Jonathan Meyer, Jordan Ursino, Joseph Im, Joseph Tramaglini, Joseph Wolken, Kaitlyn Potter, Kaitlyn Scacalossi, Kamala Naidu, Karen Browning, Karen Rutkowski, Karen Yau, Katherine Woloshin, Kelly Lewis-Amezcua, Kenneth Turner, Kimberly Dornheim, Kit Chiu, Kosalai Mohan, Kristina McGuire, Kristy Macci, Kurt Ringleben, Kusha Mohammadi, Kyle Foster, Latora Knighton, Leah Lipsich, Lindsay Darling, Lisa Boersma, Lisa Cowen, Lisa Hersh, Lisa Jackson, Lisa Purcell, Lisa Sherpinsky, Livia Lai, Lori Faria, Lori Geissler, Louise Boppert, Lyra Fiske, Marc Dickens, Marco Mancini, Maria C. Leigh, Meagan P. O'Brien, Michael Batchelder, Michael Klinger, Michael Partridge, Michel Tarabocchia, Michelle Wong, Mivianisse Rodriguez, Moetaz Albizem, Muriel O'Byrne, Nicole Deitz, Nicole Memblatt, Nirav Shah, Nitin Kumar, Olga Herrera, Oluchi Adedoyin, Ori Yellin, Pamela Snodgrass, Patrick Floody, Paul D'Ambrosio, Paul (Xiaobang) Gao, Philippa Hearld, Qin Li, Rachel Kitchenoff, Rakiyya Ali, Ramya Iyer, Ravikanth Chava, Rinol Alaj, Rita Pedraza, Robert Hamlin, Romana Hosain, Ruchin Gorawala, Ryan White, Ryan Yu, Rylee Fogarty, S. Balachandra Dass, Sagarika Bollini, Samit Ganguly, Sandra DeCicco, Sanket Patel, Sarah Cassimaty, Selin Somersan-Karakaya, Shane McCarthy, Sharon Henkel, Shazia Ali, Shelley Geila Shapiro, Somang Kim, Soraya Nossoughi, Stephanie Bisulco, Steven Elkin, Steven Long, Sumathi Sivapalasingam, Susan Irvin, Susan Wilt, Tami Min, Tatiana Constant, Theresa Devins, Thomas DiCioccio, Thomas Norton, Travis Bernardo, Tzu-Chien Chuang, Victor (Jianguo) Wei, Vinh Nuce, Vishnu Battini, Wilson Caldwell, Xiaobang Gao, Xin Chen, Yanmei Tian, Yasmin Khan, Yuming Zhao, Yunji Kim, Bonnie Dye, Christopher B. Hurt, Dale R. Burwen, Dan H. Barouch, David Burns, Elizabeth Brown, Katharine J. Bar, Mary Marovich, Meredith Clement, Myron S. Cohen, Nirupama Sista, Ruanne V. Barnabas, Sheryl Zwerski

Publikováno v: The Lancet Infectious Diseases. 22:1444-1454

There is an unmet need for COVID-19 prevention in patient populations who have not mounted or are not expected to mount an adequate immune response to complete COVID-19 vaccination. We previously reported that a single subcutaneous 1200 mg dose of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce0f85de47fd4e8285788ee5831ff8ff
https://doi.org/10.1016/s1473-3099(22)00416-9

Garetosmab, an inhibitor of activin A, reduces heterotopic ossification and flare-ups in adults with fibrodysplasia ossificans progressiva: a randomized, double-blind, placebo-controlled phase 2 trial

Autor: Maja Di Rocco, Eduardo Forleo-Neto, Robert Pignolo, Richard Keen, Philippe Orcel, Thomas Funck-Brentano, Christian Roux, Sami Kolta, Annalisa Madeo, Judith S Bubbear, Jacek Tabarkiewicz, Małgorzata Szczepanek, Javier Bachiller-Corral, Angela M Cheung, Kathryn M Dahir, Esmée Botman, Pieter G Raijmakers, Mona Al Mukaddam, Lianne Tile, Cynthia Portal-Celhay, Neena Sarkar, Peijie Hou, Bret Musser, Anita Boyapati, Kusha Mohammadi, Scott Mellis, Andrew J. Rankin, Aris N. Economides, Dinko Gonzalez Trotter, Gary Herman, Sarah J. O’Meara, Richard DelGizzi, David M. Weinreich, George D. Yancopolous, E. Marelise W. Eekhoff, Frederick S. Kaplan

BackgroundFibrodysplasia ossificans progressiva (FOP), an ultra-rare disorder caused by mutations in the gene encoding activin A receptor type 1 (ACVR1), is characterized by painful flare-ups and cumulative heterotopic ossification (HO). Garetosmab,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c882b21013c888887c75dbb8599f68a0
https://doi.org/10.1101/2023.01.11.23284254

Effect of Subcutaneous Casirivimab and Imdevimab Antibody Combination vs Placebo on Development of Symptomatic COVID-19 in Early Asymptomatic SARS-CoV-2 Infection: A Randomized Clinical Trial

Autor: Meagan P, O'Brien, Eduardo, Forleo-Neto, Neena, Sarkar, Flonza, Isa, Peijie, Hou, Kuo-Chen, Chan, Bret J, Musser, Katharine J, Bar, Ruanne V, Barnabas, Dan H, Barouch, Myron S, Cohen, Christopher B, Hurt, Dale R, Burwen, Mary A, Marovich, Elizabeth R, Brown, Ingeborg, Heirman, John D, Davis, Kenneth C, Turner, Divya, Ramesh, Adnan, Mahmood, Andrea T, Hooper, Jennifer D, Hamilton, Yunji, Kim, Lisa A, Purcell, Alina, Baum, Christos A, Kyratsous, James, Krainson, Richard, Perez-Perez, Rizwana, Mohseni, Bari, Kowal, A Thomas, DiCioccio, Gregory P, Geba, Neil, Stahl, Leah, Lipsich, Ned, Braunstein, Gary, Herman, George D, Yancopoulos, David M, Weinreich, Anya T., Weerasinghe

Publikováno v: JAMA

IMPORTANCE: Easy-to-administer anti–SARS-CoV-2 treatments may be used to prevent progression from asymptomatic infection to symptomatic disease and to reduce viral carriage. OBJECTIVE: To evaluate the effect of combination subcutaneous casirivimab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ecd30505beb30fbab21d922c4bc4bd
https://europepmc.org/articles/PMC8808333/

Subcutaneous REGEN-COV Antibody Combination for Covid-19 Prevention

Autor: Meagan P, O'Brien, Eduardo, Forleo-Neto, Bret J, Musser, Flonza, Isa, Kuo-Chen, Chan, Neena, Sarkar, Katharine J, Bar, Ruanne V, Barnabas, Dan H, Barouch, Myron S, Cohen, Christopher B, Hurt, Dale R, Burwen, Mary A, Marovich, Peijie, Hou, Ingeborg, Heirman, John D, Davis, Kenneth C, Turner, Divya, Ramesh, Adnan, Mahmood, Andrea T, Hooper, Jennifer D, Hamilton, Yunji, Kim, Lisa A, Purcell, Alina, Baum, Christos A, Kyratsous, James, Krainson, Richard, Perez-Perez, Rizwana, Mohseni, Bari, Kowal, A Thomas, DiCioccio, Neil, Stahl, Leah, Lipsich, Ned, Braunstein, Gary, Herman, George D, Yancopoulos, David M, Weinreich, Sheryl, Zwerski

Publikováno v: medRxiv
The New England Journal of Medicine

Background REGEN-COV (previously known as REGN-COV2), a combination of the monoclonal antibodies casirivimab and imdevimab, has been shown to markedly reduce the risk of hospitalization or death among high-risk persons with coronavirus disease 2019 (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d90fc31b24304d910d754a59cda51134
https://doi.org/10.1101/2021.06.14.21258567