Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Peihong, Qiu"'
Publikováno v:
Annals of Medicine, Vol 55, Iss 2 (2023)
AbstractBackground Non-alcoholic fatty liver disease (NAFLD) and gastroesophageal reflux disease (GERD) are both associated with obesity. However, the relationship of NAFLD with reflux esophagitis (RE) is still unclear in non-obese individuals.Method
Externí odkaz:
https://doaj.org/article/127a10ee1302486484c937d2eb7c0595
Autor:
Jiabing Wang, Lili Huang, Chanchan Chen, Ge Li, Jingwen Xie, Mengya Shen, Qian Chen, Wulan Li, Wenfei He, Peihong Qiu, Jianzhang Wu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 8, Pp 3451-3452 (2022)
Externí odkaz:
https://doaj.org/article/5b2b8795adba4639ba483722ec42e334
Autor:
Jiabing Wang, Lili Huang, Chanchan Cheng, Ge Li, Jingwen Xie, Mengya Shen, Qian Chen, Wulan Li, Wenfei He, Peihong Qiu, Jianzhang Wu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 9, Iss 2, Pp 335-350 (2019)
Scavenging reactive oxygen species (ROS) by antioxidants is the important therapy to cerebral ischemia-reperfusion injury (CIRI) in stroke. The antioxidant with novel dual-antioxidant mechanism of directly scavenging ROS and indirectly through antiox
Externí odkaz:
https://doaj.org/article/cbe3284e85634b2d868a53b19e1d69b3
Autor:
Qian Chen, Min Zhu, Jingwen Xie, Zhaojun Dong, Fatehi Khushafah, Di Yun, Weitao Fu, Ledan Wang, Tao Wei, Zhiguo Liu, Peihong Qiu, Jianzhang Wu, Wulan Li
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Aberrant fibroblast growth factor receptor-1 (FGFR1), a key driver promoting gastric cancer (GC) progression and chemo-resistance, has been increasingly recognized as a potential therapeutic target in GC. Hereon, we designed and synthesized a series
Externí odkaz:
https://doaj.org/article/d388896e8fc04e48a1bdf28410348c83
Autor:
Jianzhang, Wu, Yiyuan, Xi, Ge, Li, Yuantie, Zheng, Zhongle, Wang, Jingsong, Wang, Chengyan, Fang, Zhongmin, Sun, Linya, Hu, Wei, Jiang, Lishang, Dai, Jianyong, Dong, Peihong, Qiu, Min, Zhao, Pengcheng, Yan
Publikováno v:
Journal of natural products. 84(4)
Five new diterpenes, including four new hydroazulenes, (8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f430a10de03b35358ee1601ed10d206
https://pubmed.ncbi.nlm.nih.gov/33724827
https://pubmed.ncbi.nlm.nih.gov/33724827
Autor:
Yanyi Qiu, Xiaoyan Wei, Peihong Qiu, Min Zhu, Jingwen Xie, Xing Jiang, Xiaoou Zhou, Li-Ping Jiang, Jianzhang Wu, Chengxi Jiang, Wulan Li, Liping Chen, Miao Bao, Qian Chen, Jiabing Wang
Publikováno v:
European Journal of Medicinal Chemistry. 157:1395-1405
Chalcone, a natural structure, demonstrates many pharmacological activities including anticancer, and one promising mechanism is to modulate the generation of ROS. It has been known that pyroptosis is associated with anticancer effects, whereas there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc5c31cb20dc4a9e64042bfabe84ef9
https://doi.org/10.1016/j.ejmech.2018.08.072
https://doi.org/10.1016/j.ejmech.2018.08.072
Autor:
Jiafeng Zhang, Jianzhang Wu, Xiufei Yang, Dahui Chen, Wulan Li, Ziliang Fan, Peihong Qiu, Sicen Wang, Lili Huang, Shoubiao Wu, Min Zhu, Yuantie Zheng, Liping Chen, Shenghui Chu, Jiabing Wang
Publikováno v:
European Journal of Medicinal Chemistry. 143:1165-1173
Exogenous supplementation of antioxidants with ROS scavenging activity would be a potential therapy to cerebral ischemia-reperfusion injury in stroke. In the present study, a series of NDGA analogues with attenuation oxidative stress by directly scav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc803fbd381529a6a6b46bd476af4288
https://doi.org/10.1016/j.ejmech.2017.09.028
https://doi.org/10.1016/j.ejmech.2017.09.028
Autor:
Tao Wei, Wulan Li, Jiali Yao, Jianzhang Wu, Di Yun, Cuijuan Yu, Haineng Xu, Xiaoou Zhou, Peihong Qiu, Yanqing Huang, Liping Chen, Fangyan Huang, Jiabing Wang, Weitao Fu
Publikováno v:
European Journal of Medicinal Chemistry. 144:493-503
Molecular hybridization is considered as an effective tactic to develop drugs for the treatment of cancer. A series of novel hybrid compounds of isatin and Michael acceptor were designed and synthesized on the basis of association principle. These hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a4833555d7d1747122eb966974999b2
https://doi.org/10.1016/j.ejmech.2017.12.043
https://doi.org/10.1016/j.ejmech.2017.12.043
Autor:
Yangyang Zhou, Rong Jin, Qing Xu, Jianzhang Wu, Yanting Kang, Min Zhu, Peng Zhou, Guang Liang, Shanshan Zhang, Wulan Li, Dahui Chen, Jiabing Wang, Peihong Qiu
Publikováno v:
European Journal of Medicinal Chemistry. 139:917-925
NF-κB is a critical target for cancer treatment due to its central role in facilitating cancer progression and desensitizing cancer cells to chemotherapeutic drugs. In this study, a series of chemically modified asymmetric curcuminoid analogs named
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5688c186fcba9007e672b897963e447f
https://doi.org/10.1016/j.ejmech.2017.08.022
https://doi.org/10.1016/j.ejmech.2017.08.022
Autor:
Xiaojing Du, Encheng Bai, Qing Xu, Weitao Fu, Yuepiao Cai, Yangyang Zhou, Di Yun, Guang Liang, Peihong Qiu, Rong Jin, Wulan Li, Qiuxiang Chen, Jianzhang Wu, Yanting Kang
Publikováno v:
Apoptosis. 22:852-864
Fibroblast growth factor receptor 1 (FGFR1), belonging to receptor tyrosine kinases (RTKs), possesses various biological functions. Over-expression of FGFR1 has been observed in multiple human malignancies. Hence, targeting FGFR1 is an attractive pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1248852075131b8a70bded844f6459cc
https://doi.org/10.1007/s10495-017-1361-7
https://doi.org/10.1007/s10495-017-1361-7