Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Peichang Wang"'
Autor:
Xiaoling Wang, Xiaomin Zhang, Jing Liu, Jingjing Zhang, Congcong Liu, Yuting Cui, Qiao Song, Yuli Hou, Yaqi Wang, Qian Zhang, Yingzhen Zhang, Yujian Fan, Jianping Jia, Peichang Wang
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-18 (2024)
Abstract Background Previous studies have demonstrated that early intervention was the best plan to inhibit the progression of Alzheimer’s disease (AD), which relied on the discovery of early diagnostic biomarkers. In this study, synaptic vesicle g
Externí odkaz:
https://doaj.org/article/416dba92365c4d508a69707518e6cb4f
Autor:
Min Cao, Jing Liu, Xiaomin Zhang, Yaqi Wang, Yuli Hou, Qiao Song, Yuting Cui, Yue Zhao, Peichang Wang
Publikováno v:
Immunity & Ageing, Vol 20, Iss 1, Pp 1-13 (2023)
Abstract Background Alzheimer’s disease (AD), which is the most common cause of dementia in elderly individuals, is a progressive neurodegenerative disorder. Neuroinflammation, which is an immune response that is activated by glial cells in the cen
Externí odkaz:
https://doaj.org/article/9d42f53bd7d64142a23e9ef1b5a29092
Publikováno v:
European Journal of Medical Research, Vol 28, Iss 1, Pp 1-8 (2023)
Abstract Objective To investigate the factors influencing the degree of disability in patients with neuromyelitis optica spectrum disorder (NMOSD) and provide evidence for disease monitoring and clinical intervention. Methods Eighty-four patients wit
Externí odkaz:
https://doaj.org/article/757c4031f275441ebd04460c4634d84e
Publikováno v:
Journal of Medical Biochemistry, Vol 42, Iss 2, Pp 258-264 (2023)
Background: This study aims to establish reference intervals (RIs) for thyroid hormones in the elderly population and analyze their influence on the prevalence of subclinical hypothyroidism. Methods: Thyroid hormone records of subjects who underwent
Externí odkaz:
https://doaj.org/article/e2ec3b20fabb40c78bbd58d4caf42269
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-15 (2022)
Abstract Background The deposition of β-amyloid (Aβ) in the brain plays a major role in the pathogenesis of Alzheimer’s disease (AD). Aβ is generated via amyloid precursor protein (APP) cleavage through the amyloidogenic pathway. In this pathway
Externí odkaz:
https://doaj.org/article/806fca1879e74f7cb5cc43905fd2dbad
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 160, Iss , Pp 114276- (2023)
Externí odkaz:
https://doaj.org/article/511d49506afd46c98938ffaafb58811d
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2020)
Abstract Background The pathological hallmarks of Alzheimer’s disease (AD) involve alterations in the expression of numerous genes associated with transcriptional levels, which are determined by chromatin accessibility. Here, the landscape of chrom
Externí odkaz:
https://doaj.org/article/d3b680e0f52140638f53b887b6c3296f
Publikováno v:
Radiation Oncology, Vol 14, Iss 1, Pp 1-5 (2019)
Abstract At present, the standard treatment approach for locally advanced cervical cancer is concurrent chemoradiotherapy (CCRT). An elevated pretreatment squamous cell carcinoma antigen (SCC Ag) level is associated with extensive tumors and poor sur
Externí odkaz:
https://doaj.org/article/efab9c44a0d14c1a9139335a439f3d53
Autor:
Yuli Hou, Qiao Song, Shichao Gao, Xiaomin Zhang, Yaqi Wang, Jing Liu, Jingxuan Fu, Min Cao, Peichang Wang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
POLD1, the catalytic subunit of DNA polymerase δ, plays a critical role in DNA synthesis and DNA repair processes. Moreover, POLD1 is downregulated in replicative senescence to mediate aging. In any case, the components of age-related downregulation
Externí odkaz:
https://doaj.org/article/e23bd912362c4709aaac9e30db28c481
Autor:
Jing Liu, Yu Liu, Jingxuan Fu, Chengeng Liu, Tingting Yang, Xiaomin Zhang, Min Cao, Peichang Wang
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 8, Pp n/a-n/a (2020)
Abstract Background Fanconi anemia (FA) is a rare recessive disease characterized by DNA damage repair deficiency, and DNA polymerase δ (whose catalytic subunit is encoded by POLD1, also known as CDC2) is closely related to DNA damage repair. Our pr
Externí odkaz:
https://doaj.org/article/2b69c0c957ae41ca9724e18cf5450ff1