Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Pei-Zhou Ni"'
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1999 9(14):1933-1936
Publikováno v:
Chinese Journal of Natural Medicines. 8:436-440
Publikováno v:
Chinese Journal of Natural Medicines. 8:441-448
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:783-788
1-(2,6-dimethylphenoxy)-2-(3,4-dimethoxyphenylethylamino)propane hydrochloride (DDPH) is a potent α₁-adrenoceptor antagonist that is currently under Phase II clinic trials. However, the fast metabolism has restricted its further use. In this paper
Autor:
Shou-Hua Zhang, Jin-Pei Zhou, Wang Chunye, Bao-Min Xi, Zhen-Zhou Jiang, Wen-Hua Chen, Pei-Zhou Ni
Publikováno v:
Chemical and Pharmaceutical Bulletin. 59:96-99
This paper describes the synthesis and blocking activities of twelve new isoindolinone- and isobenzofuranone-containing phenoxylalkylamines as potent α(1)-Adrenoceptor antagonists. These compounds were synthesized in moderate to good yields starting
Publikováno v:
Chinese Journal of Natural Medicines. 8:441-448
Aim To study glycogen phosphorylase inhibitory activity of natural pentacyclic triterpenes bearing 23-hydroxy or 24-hydroxy. Methods Arjunolic acid, bayogenin, hederagonic acid and 4- epi -hederagonic acid were synthesized from oleanolic acid as the
Autor:
Pei-Zhou Ni, Huibin Zhang, Tao Wang, Dian-Qing Wu, Wen-Hua Chen, Zhen-Zhou Jiang, Bao-Min Xi, Shou-Hua Zhang
Publikováno v:
Chemical Biology & Drug Design. 76:505-510
Finding effective chemotherapeutic agents for clinical use is a long-lasting goal in medicinal chemistry. In this study, we report a new class of α1-adrenoceptor (α1-AR) antagonists. Specifically, we describe the synthesis and the blocking activiti
Autor:
Wang Chunye, Zhen-Zhou Jiang, Shou-Hua Zhang, Bao-Min Xi, Jin-Pei Zhou, Wen-Hua Chen, Pei-Zhou Ni
Publikováno v:
ChemInform. 42
New isoindolinone- and isobenzofuranone-containing phenoxyalkylamines (V) and (VIII), resp., are synthesized and evaluated for their blocking activities toward α1-adrenoceptors.
Autor:
Bao-Min, Xi, Pei-Zhou, Ni, Zhen-Zhou, Jiang, Dian-Qing, Wu, Shou-Hua, Zhang, Hui-Bin, Zhang, Tao, Wang, Wen-Hua, Chen
Publikováno v:
Chemical biologydrug design. 76(6)
Finding effective chemotherapeutic agents for clinical use is a long-lasting goal in medicinal chemistry. In this study, we report a new class of α₁-adrenoceptor (α₁-AR) antagonists. Specifically, we describe the synthesis and the blocking acti
Publikováno v:
Tetrahedron. 46:3431-3438
Heating of 5-carbamoyl- (1) and 5-thiocarbamoyl-3-methyl-1-phenyluracil (5) derivatives in ethanolic sodium ethoxide causes a novel intramolecular rearrangement to give 5-anilinomethylenebarbituric acids(2) and 5-anilinomethylene-4-thiobarbituric and