Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Pei-Liang Zhao"'
Autor:
Pei-Liang Zhao, Zhong-Zhen Zhou
Publikováno v:
Acta Crystallographica Section E, Vol 65, Iss 8, Pp o2030-o2031 (2009)
The title molecule, C18H14N2O5S·C3H7NO, comprises of a carboxamide group bonded to a furan ring and a distorted envelope-shaped 4-oxothiazolidin-3-yl group which is connected to a substituted 6-methyl-4-oxo-4H-chromen-3-yl group. Extensive strong N
Externí odkaz:
https://doaj.org/article/0bfd88e197ad4dfba92ce4398dcd4113
Autor:
Xian‐Sen Huo, Ji Tang‐Yang, Wen‐Bin Zeng, Xie‐Er Jian, Xuan‐Xuan Ma, Peng Yue‐Yang, You Wen‐Wei, Pei‐Liang Zhao
Publikováno v:
Drug Development Research.
Autor:
Jiewei Jiang, Pei‐Liang Zhao, Logan H. Sigua, Alice Chan, Ernst Schönbrunn, Jun Qi, Gunda I. Georg
Publikováno v:
Archiv der Pharmazie. 355(11)
Based on a previously reported 1,4-dihydropyridinebutyrolactone virtual screening hit, nine lactone ring-opened ester and seven amide analogs were prepared. The analogs were designed to provide interactions with residues at the entrance of the ZA loo
Publikováno v:
Bioorganicmedicinal chemistry letters. 75
Based on our previous work, a series of novel 6-arylamino-[1,2,4]triazolo[4,3-a]pyridine derivatives were synthesized, and evaluated for antiproliferative activities. SAR studies revealed that inserting an amino linkage between 6‑aryl group and [1,
Publikováno v:
New Journal of Chemistry. 45:21869-21880
Thirty-six novel indole-based 1,2,4-triazole derivatives were designed and synthesized through the molecular hybrid strategy. The bioassay results revealed that 9p displayed excellent antiproliferative efficacies in the nanomolar range against HeLa c
Publikováno v:
Bioorganicmedicinal chemistry letters. 66
Based on our previous work, a series of novel triazolylthioacetones incorporating pyridine, pyrazine, and 3,4,5-trimethoxybenzyl fragment were synthesized, and evaluated for antiproliferative activities and interactions with tubulin. Some analogues e
Publikováno v:
Physical Review B. 104
In this paper, we theoretically investigated the electronic properties of monolayer $\mathrm{Mo}{\mathrm{Si}}_{2}{\mathrm{N}}_{4}$ by combining first-principles calculations and symmetry analyses. Spin-orbital coupling resulted in band splitting, whe
Autor:
You Wenwei, Xiao-Lan Zheng, Jin-Mei Lai, Xiong-Li Li, Li-Yuan Wei, Fang Yang, Xie-Er Jian, Lin Chen, Dong-Xin Lv, Pei-Liang Zhao, Yu-Xia Liu, Li-Li Yuan, Feng-Ting Liang
Publikováno v:
Bioorganicmedicinal chemistry letters. 38
Based on our previous research, thirty new 5-amino-1H-1,2,4-triazoles possessing 3,4,5-trimethoxyphenyl moiety were synthesized, and evaluated for antiproliferative activities. Among them, compounds IIa, IIIh, and IIIm demonstrated significant antipr
Autor:
Pei-Liang Zhao, Ren-Xin He, Yu-Feng Ma, Wen-Wei You, Qiu Li, Xian-Sen Huo, Lin Chen, Xie-Er Jian, Yu Wang
Publikováno v:
Bioorganicmedicinal chemistry letters. 31
Based on our previous work, a novel class of 8-cyclopentyl-7,8-dihydropteridin-6(5H)-one derivatives were synthesized and evaluated as antiproliferative agents. Structure-activity relationship analysis revealed that the greatest activities were achie
Autor:
Wen-Wei You, Qiu Li, Jin-Jun Rao, Lin Chen, Xie-Er Jian, Zi-Hua Li, Pei-Liang Zhao, Xian-Sen Huo, Zhi-Ru Chen
Publikováno v:
Bioorganic chemistry. 102
A new series of derivatives characterized by the presence of the 3,4,5-trimethoxylbenzamide substituted benzofurans were synthesized and evaluated for antiproliferative activity against four cancer cell lines and one normal human cell line. Among the