Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Pei-Juan Shen"'
Publikováno v:
Neuropharmacology. 58:145-155
Relaxin-3 (RLX3), a newly identified member of the relaxin peptide family, is distinguished by its enriched expression in GABA projection neurons of the pontine nucleus incertus (NI), which are postulated to participate in forebrain neural circuits i
Autor:
Katayoun Sedaghat, Steve W. Sutton, Craig M. Smith, Timothy W. Lovenberg, David Finkelstein, Andrew J Lawrence, Sherie Ma, Changlu Liu, John D. Wade, Andrew L. Gundlach, Loretta Piccenna, Qian Sang, Pascal Bonaventure, Ross A. D. Bathgate, Geoffrey W. Tregear, Pei Juan Shen
Publikováno v:
Annals of the New York Academy of Sciences. 1160:226-235
As a foundation for regulatory and functional studies of central relaxin family peptide receptor systems, we are mapping the distribution of the different receptors in the brain of rat, mouse, and nonhuman primates, attempting to identify the nature
Autor:
Chong-Gang Yuan, Shuang Cheng, Ji Ma, Ann M. Turnley, Andrew L. Gundlach, May. Yao, Pei-Juan Shen
Publikováno v:
Neuropeptides. 39:201-205
Considerable recent evidence suggests that in addition to its neuromodulatory role, galanin, like several other neuropeptides, also plays an important trophic role during development and after adult neural injury. Studies in our laboratory have ident
Autor:
Tanya C. D. Burazin, Sherie Ma, Ross A. D. Bathgate, Loretta Piccenna, Sietse Mosselman, Andrew L. Gundlach, Pei-Juan Shen, Jan A. Gossen
Publikováno v:
Annals of the New York Academy of Sciences. 1041:197-204
Knowledge of the distribution of the relaxin receptor, LGR7, in the brain provides a basis for studies of the physiologic actions of relaxin. LGR7 knock-out (KO) mice were produced by the in-frame replacement of LGR7 exon 10 and 11 with a LacZ-report
Autor:
John D. Wade, Pei-Juan Shen, Ping Fu, Chongxin Zhao, Ross A. D. Bathgate, Andrew L. Gundlach, Chrishan S. Samuel, Geoffrey W. Tregear, Daniel Scott
Publikováno v:
Annals of the New York Academy of Sciences. 1041:516-519
Recent molecular and pharmacologic studies have identified LGR8, a member of the leucine-rich repeat-containing G-protein-coupled receptor family, as a cognate receptor for insulin-like peptide-3 (INSL3). LGR8 mRNA has been detected in various tissue
Autor:
Kevin D. Phelan, Sharon Layfield, Pei-Juan Shen, Geoffrey W. Tregear, Ping Fu, Ross A. D. Bathgate, Daniel Scott, Andrew L. Gundlach
Publikováno v:
Annals of the New York Academy of Sciences. 1041:510-515
LGR8 was recently identified as a cognate receptor for insulin-like peptide-3 (INSL3), and INSL3-LGR8 signaling is best known for its role in testis descent during development. LGR8 mRNA has been detected in various human tissues including brain, but
Publikováno v:
Journal of Neurochemistry. 92:1452-1462
Galanin is a modulator of fast transmission in adult brain and recent evidence suggests that it also acts as a trophic factor during neurogenesis and neural injury and repair. Previous studies in our laboratory have identified galanin mRNA in Purkinj
Publikováno v:
Journal of Neurochemistry. 87:1368-1380
Cortical spreading depression (CSD) is characterized by slowly propagating waves of neuronal/astrocytic depolarization and metabolic changes, followed by a period of quiescent neuronal and electroencephalographic activity. CSD acts as a preconditioni
Publikováno v:
Bone. 33:788-797
The neuropeptide galanin (GAL) has recognized physiological actions in the nervous system and other tissues, but there is no documented evidence of GAL influencing normal or pathological bone metabolism. GAL expression, however, is upregulated in cen
Publikováno v:
Molecular Brain Research. 114:20-30
Clusterin is a sulfated glycoprotein produced by neurons and by resting and activated astrocytes that has several putative functions, including protective responses to brain injury. Cortical spreading depression (CSD) is a powerful yet largely benign