Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Pei-Hua Peng"'
Autor:
Pei-Hua Peng, Ji-Lin Chen, Heng-Hsiung Wu, Wen-Hao Yang, Li-Jie Lin, Joseph Chieh-Yu Lai, Jeng-Shou Chang, Jia-Ling Syu, Han-Tsang Wu, Fei-Ting Hsu, Wei-Chung Cheng, Kai-Wen Hsu
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background The hypoxia-responsive long non-coding RNA, RP11-367G18.1, has recently been reported to induce histone 4 lysine 16 acetylation (H4K16Ac) through its variant 2; however, the underlying molecular mechanism remains poorly understood
Externí odkaz:
https://doaj.org/article/8dd4697709b048498ccf690dad5a8067
Autor:
I‐Hung Shao, Pei‐Hua Peng, Heng‐Hsiung Wu, Ji‐Lin Chen, Joseph Chieh‐Yu Lai, Jeng‐Shou Chang, Han‐Tsang Wu, Kou‐Juey Wu, See‐Tong Pang, Kai‐Wen Hsu
Publikováno v:
Cancer Medicine, Vol 12, Iss 8, Pp 9788-9801 (2023)
Abstract Purpose Metastasis is the end stage of renal cell carcinoma (RCC), and clear cell renal cell carcinoma (ccRCC) is the most common malignant subtype. The hypoxic microenvironment is a common feature in ccRCC and plays an essential role in the
Externí odkaz:
https://doaj.org/article/0a9475d585f249369bc43712fd3e745c
Autor:
Kai-Wen Hsu, Joseph Chieh-Yu Lai, Jeng-Shou Chang, Pei-Hua Peng, Ching-Hui Huang, Der-Yen Lee, Yu-Cheng Tsai, Chi-Jung Chung, Han Chang, Chao-Hsiang Chang, Ji-Lin Chen, See-Tong Pang, Ziyang Hao, Xiao-Long Cui, Chuan He, Kou-Juey Wu
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-37 (2022)
Abstract Background DNA N6-methyldeoxyadenosine (6mA) is rarely present in mammalian cells and its nuclear role remains elusive. Results Here we show that hypoxia induces nuclear 6mA modification through a DNA methyltransferase, METTL4, in hypoxia-in
Externí odkaz:
https://doaj.org/article/6c0fad365ca1454eb69e277ce3013571
Autor:
Chia-Hsin Liu, Shu-Hsuan Liu, Yo-Liang Lai, Yi-Chun Cho, Fang-Hsin Chen, Li-Jie Lin, Pei-Hua Peng, Chia-Yang Li, Shu-Chi Wang, Ji-Lin Chen, Heng-Hsiung Wu, Min-Zu Wu, Yuh-Pyng Sher, Wei-Chung Cheng, Kai-Wen Hsu
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 4626-4635 (2022)
Lung cancer is a major cause of cancer-associated deaths worldwide, and lung adenocarcinoma (LUAD) is the most common lung cancer subtype. Micro RNAs (miRNAs) regulate the pattern of gene expression in multiple cancer types and have been explored as
Externí odkaz:
https://doaj.org/article/0142da904d0e48d8bb1bb3790a3773d0
Publikováno v:
Biomedical Journal, Vol 44, Iss 5, Pp 521-533 (2021)
Long noncoding RNAs (lncRNAs) are noncoding RNAs with length greater than 200 nt. The biological roles and mechanisms mediated by lncRNAs have been extensively investigated. Hypoxia is a proven microenvironmental factor that promotes solid tumor meta
Externí odkaz:
https://doaj.org/article/86ef44f5776c45a98ea67ef8c448ff89
Autor:
Yumei Qi, Yo-Liang Lai, Pei-Chun Shen, Fang-Hsin Chen, Li-Jie Lin, Heng-Hsiung Wu, Pei-Hua Peng, Kai-Wen Hsu, Wei-Chung Cheng
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Abstract Cervical cancer is the fourth most common cancer in women worldwide. Increasing evidence has shown that miRNAs are related to the progression of cervical cancer. However, the mechanisms that affect the prognosis of cancer are still largely u
Externí odkaz:
https://doaj.org/article/12a635dbd4f94295b89f26b127f24e09
Autor:
Pei-Hua Peng, Yajuan Chen, Rong Huang, Chen Chen, Liu-Yi Zhang, Meng-Yuan Li, Weimin Yang, Qing-Qing Li, Chun-Yun Bai, Xing-Wei Zhu, Xiu-Juan Zhang
Publikováno v:
Natural Products and Bioprospecting
Flavonoid glycoside scutellarin (SCU) has been widely applied in the treatment of cerebral ischemic diseases in China. In this article, we conducted research on the working mechanisms of SCU in hypoxia reoxygenation (HR) injury of isolated cerebral b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b401e1af8b3ea066ef84e0b97a29d339
http://europepmc.org/articles/PMC8599605
http://europepmc.org/articles/PMC8599605
Publikováno v:
Clinical Epigenetics
Background Glioblastoma (GBM) is a malignant human brain tumor that has an extremely poor prognosis. Classic mutations such as IDH (isocitrate dehydrogenase) mutations, EGFR (epidermal growth factor receptor) alternations, and MGMT (O6-methylguanine-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab810fb1031f6e805d0106ed3f10f17
https://doi.org/10.1186/s13148-021-01181-8
https://doi.org/10.1186/s13148-021-01181-8
Publikováno v:
Am J Cancer Res
Hypoxia activates various long noncoding RNAs (lncRNAs) to induce the epithelial-mesenchymal transition (EMT) and tumor metastasis. The hypoxia/HIF-1α-regulated lncRNAs that also regulate a specific histone mark and promote EMT and metastasis have n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d7f168a06908c8121b811f9c212471c2
https://pubmed.ncbi.nlm.nih.gov/34249418
https://pubmed.ncbi.nlm.nih.gov/34249418
Autor:
Wei-Chung Cheng, Kai Wen Hsu, Hsiu Ju Yang, Heng Hsiung Wu, Shun-Fa Yang, Lung Hung Tsai, Cheng Ming Chiang, Yu Huei Liu, Pei Hua Peng
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Pancreatic cancer is the fourth leading cause of death worldwide due to its poorest prognoses with a 7% 5-year survival rate. Eighty percent of pancreatic cancer patients relapse after chemotherapy and develop early metastasis and drug resistance. Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd3c32f19e030526c23ba90bc0de56bf
https://pubmed.ncbi.nlm.nih.gov/33082357
https://pubmed.ncbi.nlm.nih.gov/33082357