Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates

Autor: Ronald Melki, Ron R. Kopito, Jane E. Lauckner, Pei-Hsien Ren, John E. Heuser, Ioulia Kachirskaia

Publikováno v: Nature Cell Biology
Nature Cell Biology, Nature Publishing Group, 2009, 11 (2), pp.219-25. ⟨10.1038/ncb1830⟩

International audience; Sequence-specific nucleated protein aggregation is closely linked to the pathogenesis of most neurodegenerative diseases and constitutes the molecular basis of prion formation. Here we report that fibrillar polyglutamine pepti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e35648518b3440ff1fdb5f268089bc1
https://doi.org/10.1038/ncb1830

Transgenic barley grain overexpressing thioredoxin shows evidence that the starchy endosperm communicates with the embryo and the aleurone.

Autor: Wong, Joshua H., Yong-Bum Kim, Pei-Hsien Ren, Cai, Nick, Myeong-Je Cho, Hedden, Peter, Lemaux, Peggy G., Buchanan, Bob B.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America; 12/10/2002, Vol. 99 Issue 25, p16325, 6p, 7 Black and White Photographs, 1 Diagram, 6 Graphs

The Black Box of Biology : A History of the Molecular Revolution

Autor: Michel Morange

In this masterful account, a historian of science surveys the molecular biology revolution, its origin and continuing impact.Since the 1930s, a molecular vision has been transforming biology. Michel Morange provides an incisive and overarching histor