Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Pei-Fen Kuan"'
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Proteomics provides an opportunity to develop biomarkers for the early detection and monitoring of post-traumatic stress disorder (PTSD). However, research to date has been limited by small sample sizes and a lack of replication. This study
Externí odkaz:
https://doaj.org/article/d98db2477803416eb7be0979343ed194
Autor:
Ginny Natale, Minos Kritikos, Pei-Fen Kuan, Melissa A. Carr, Xiaohua Yang, Yuan Yang, Roman Kotov, Evelyn J. Bromet, Sean A.P. Clouston, Benjamin J. Luft
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 30, Iss , Pp 100631- (2023)
Background: Chronically re-experiencing the memory of a traumatic event might cause a glial response. This study examined whether glial activation would be associated with PTSD in a study of responders present after the 9/11 World Trade Center attack
Externí odkaz:
https://doaj.org/article/e9bfe056278d4f3aac94223c12c5f39c
Publikováno v:
Epigenetics, Vol 17, Iss 10, Pp 1281-1298 (2022)
Animal domestication is a process of environmental modulation and artificial selection leading to permanent phenotypic modifications. Recent studies showed that phenotypic changes occur very early in domestication, i.e., within the first generation i
Externí odkaz:
https://doaj.org/article/e0d75a6559f94930bf85a082ed94e34d
Autor:
Farrukh M. Koraishy, Frank D. Mann, Monika A. Waszczuk, Pei-Fen Kuan, Katherine Jonas, Xiaohua Yang, Anna Docherty, Andrey Shabalin, Sean Clouston, Roman Kotov, Benjamin Luft
Publikováno v:
BMC Nephrology, Vol 23, Iss 1, Pp 1-10 (2022)
Abstract Background The factors associated with estimated glomerular filtrate rate (eGFR) decline in low risk adults remain relatively unknown. We hypothesized that a polygenic risk score (PRS) will be associated with eGFR decline. Methods We analyze
Externí odkaz:
https://doaj.org/article/74d6162379124cb5adce09381062222c
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract Metabolomics has yielded promising insights into the pathophysiology of post-traumatic stress disorder (PTSD). The current study expands understanding of the systems-level effects of metabolites by using global metabolomics and complex lipid
Externí odkaz:
https://doaj.org/article/d3f7936ed5f741feb17622e509c93c45
Autor:
Sean A. P. Clouston, Minos Kritikos, Chuan Huang, Pei-Fen Kuan, Paul Vaska, Alison C. Pellecchia, Stephanie Santiago-Michels, Melissa A. Carr, Sam Gandy, Mary Sano, Evelyn J. Bromet, Roberto G. Lucchini, Benjamin J. Luft
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Prior research has demonstrated high levels of cognitive and physical functional impairments in World Trade Center (WTC) responders. A follow-up neuroimaging study identified changes to white matter connectivity within the cerebellum in resp
Externí odkaz:
https://doaj.org/article/0e81a4e73e8c4b148cf187dc4176e9e3
Autor:
Irene Orlow, Keimya D Sadeghi, Sharon N Edmiston, Jessica M Kenney, Cecilia Lezcano, James S Wilmott, Anne E Cust, Richard A Scolyer, Graham J Mann, Tim K Lee, Hazel Burke, Valerie Jakrot, Ping Shang, Peter M Ferguson, Tawny W Boyce, Jennifer S Ko, Peter Ngo, Pauline Funchain, Judy R Rees, Kelli O'Connell, Honglin Hao, Eloise Parrish, Kathleen Conway, Paul B Googe, David W Ollila, Stergios J Moschos, Eva Hernando, Douglas Hanniford, Diana Argibay, Christopher I Amos, Jeffrey E Lee, Iman Osman, Li Luo, Pei-Fen Kuan, Arshi Aurora, Bonnie E Gould Rothberg, Marcus W Bosenberg, Meg R Gerstenblith, Cheryl Thompson, Paul N Bogner, Ivan P Gorlov, Sheri L Holmen, Elise K Brunsgaard, Yvonne M Saenger, Ronglai Shen, Venkatraman Seshan, Eduardo Nagore, Marc S Ernstoff, Klaus J Busam, Colin B Begg, Nancy E Thomas, Marianne Berwick, InterMEL Consortium
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0269324 (2023)
IntroductionWe are conducting a multicenter study to identify classifiers predictive of disease-specific survival in patients with primary melanomas. Here we delineate the unique aspects, challenges, and best practices for optimizing a study of gener
Externí odkaz:
https://doaj.org/article/2122630446b94345873b74cdda1850a8
Autor:
Minos Kritikos, Erica D. Diminich, Jaymie Meliker, Michelle Mielke, David A. Bennett, Caleb E. Finch, Sam E. Gandy, Melissa A. Carr, Xiaohua Yang, Roman Kotov, Pei‐Fen Kuan, Evelyn J. Bromet, Sean A. P. Clouston, Benjamin J. Luft
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 1, Pp n/a-n/a (2023)
Abstract Introduction World Trade Center (WTC) responders are experiencing a high risk of mild cognitive impairment (MCI) and dementia, though the etiology remains inadequately characterized. This study investigated whether WTC exposures and chronic
Externí odkaz:
https://doaj.org/article/c4843fc99af04f9998d0e856cd5b5a46
Autor:
Pei-Fen Kuan, Xiaohua Yang, Xu Ren, Chang Che, Monika Waszczuk, Roman Kotov, Sean Clouston, Prashant K. Singh, Sean T. Glenn, Eduardo Cortes Gomez, Jianmin Wang, Evelyn Bromet, Benjamin J. Luft
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Gene expression has provided promising insights into the pathophysiology of post-traumatic stress disorder (PTSD); however, specific regulatory transcriptomic mechanisms remain unknown. The present study addressed this limitation by performi
Externí odkaz:
https://doaj.org/article/af1faf7971174a87a2b57a250711aea3
Autor:
Pei-Fen Kuan, Xu Ren, Sean Clouston, Xiaohua Yang, Katherine Jonas, Roman Kotov, Evelyn Bromet, Benjamin J. Luft
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Posttraumatic stress disorder (PTSD) is associated with shortened lifespan and healthspan, which suggests accelerated aging. Emerging evidence suggests that methylation age may be accelerated in PTSD. It is important to examine whether trans
Externí odkaz:
https://doaj.org/article/853cd0ef7e5b4bdcb833a7815d2dad2a