Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Pei Zhuo Zhang"'
Autor:
Hadi AlShamaileh, Tao Wang, Dongxi Xiang, Wang Yin, Phuong Ha-Lien Tran, Roberto A. Barrero, Pei-Zhuo Zhang, Yong Li, Lingxue Kong, Ke Liu, Shu-Feng Zhou, Yingchun Hou, Sarah Shigdar, Wei Duan
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-4 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/e559f7b26aac495ca515d9447f0a7fff
Autor:
Hadi AlShamaileh, Tao Wang, Dongxi Xiang, Wang Yin, Phuong Ha-Lien Tran, Roberto A. Barrero, Pei-Zhuo Zhang, Yong Li, Lingxue Kong, Ke Liu, Shu-Feng Zhou, Yingchun Hou, Sarah Shigdar, Wei Duan
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract The development of chemoresistance and inability in elimination of cancer stem cells are among the key limitations of cancer chemotherapy. Novel molecular therapeutic strategies able to overcome such limitations are urgently needed for futur
Externí odkaz:
https://doaj.org/article/2f03ea427ce84c7a8ed4ee36eb475dc2
Autor:
Pei-Zhuo Zhang, Yong Li, Changying Chen, Tao Wang, Tuong Ngoc-Gia Nguyen, Qingxia Zhao, Weihong Zhang, Wei Duan, Yingchun Hou, Miaomiao Sun, Phuong H.L. Tran, Kuisheng Chen, Wang Yin, Hadi AlShamaileh, Yumei Zhang
Publikováno v:
Human gene therapy methods. 30(1)
As a nucleic acid alternative to traditional antibody, aptamer holds great potential in various fields of biology and medicine such as targeted gene therapy, drug delivery, bio-sensing, and laboratory medicine. Over the past decades, the conventional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b120b405c37a27016b5adb2ba63c367
https://pubmed.ncbi.nlm.nih.gov/30700146
https://pubmed.ncbi.nlm.nih.gov/30700146
Autor:
Wei Duan, Shu-Feng Zhou, Hadi AlShamaileh, Ke Liu, Sarah Shigdar, Roberto A. Barrero, Pei Zhuo Zhang, Lingxue Kong, Yingchun Hou, Phuong H.L. Tran, Dongxi Xiang, Wang Yin, Yong Li, Tao Wang
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
The development of chemoresistance and inability in elimination of cancer stem cells are among the key limitations of cancer chemotherapy. Novel molecular therapeutic strategies able to overcome such limitations are urgently needed for future effecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8576f28fcb7df562ec5e8c745881667b
https://doi.org/10.1038/s41598-017-05859-z
https://doi.org/10.1038/s41598-017-05859-z
Autor:
Tao Wang, Yong Li, Phuong H.L. Tran, Yingchun Hou, Aina He, Lingxue Kong, Roberto A. Barrero, Shu-Feng Zhou, Wang Yin, Hadi Al. Shamaileh, Pei Zhuo Zhang, Wenrong Yang, Dongxi Xiang, Wei Duan, Sarah Shigdar, Matthew Bruce, Ke Liu, Andrew G. D. Bean, Motilal Mathesh
Publikováno v:
Theranostics
Chemotherapy-resistant cancer stem cells (CSCs) are a major obstacle to the effective treatment of many forms of cancer. To overcome CSC chemo-resistance, we developed a novel system by conjugating a CSC-targeting EpCAM aptamer with doxorubicin (Apt-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d20854bde813039f6cacd33f0b7bb25e
https://pubmed.ncbi.nlm.nih.gov/29158811
https://pubmed.ncbi.nlm.nih.gov/29158811
Autor:
Pei-Zhuo Zhang, Song Shen, Shuang Dou, Yang Liu, Meng-Hua Xiong, Xiao-Jiao Du, Chengqiong Mao, Jun Wang, Xianzhu Yang
Publikováno v:
Molecular Therapy. 22(5):964-973
The KRAS mutation is present in ~20% of lung cancers and has not yet been effectively targeted for therapy. This mutation is associated with a poor prognosis in non-small-cell lung carcinomas (NSCLCs) and confers resistance to standard anticancer tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b5a8a7fdf3ea4442e9e7e557335e5af
Autor:
Su-Bo Qian, Xin-Yan Li, Xian-Jun Zhou, Pei-Zhuo Zhang, Yong-Xiang Wang, Yan-Chao Wang, Xiao-Ling Chen
Publikováno v:
Biochemical and Biophysical Research Communications. 421:501-507
A series of inhibitors of d-amino acid oxidase (DAAO) are specific in blocking chronic pain, including formalin-induced tonic pain, neuropathic pain and bone cancer pain. This study used RNA interference technology to further validate the notion that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d641067785c4a607bae4a1c358ca8f73
https://doi.org/10.1016/j.bbrc.2012.04.030
https://doi.org/10.1016/j.bbrc.2012.04.030
Autor:
Songyin Huang, Jin-Zhi Du, Yandan Yao, Jun Wang, Erwei Song, Kam W. Leong, Chengqiong Mao, Pei-Zhuo Zhang, Shuang Dou, Tianmeng Sun
Publikováno v:
ACS Nano. 5:1483-1494
Combination of two or more therapeutic strategies with different mechanisms can cooperatively prohibit cancer development. Combination of chemotherapy and small interfering RNA (siRNA)-based therapy represents an example of this approach. Hypothesizi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a625e565071ccc2e1839beb9b025e521
https://doi.org/10.1021/nn103349h
https://doi.org/10.1021/nn103349h
Autor:
Yuanyu Huang, Pei-Zhuo Zhang, Jianguo Ji, Junmei Hong, Zhen Xi, Huang Huang, Quan Du, Jun Li, Na Wei, Zicai Liang, Yongqiang Shan, Jie Zheng, Fan Yi, Mingrui An, Hong-Yan Zhang
Publikováno v:
The FASEB Journal. 24:4844-4855
Double-stranded small interfering RNAs (siRNAs) are important modulators of biological processes and hold great promise for therapeutic applications. However, serum processing of synthetic siRNAs is still largely unknown. To address this issue, serum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee8be5c7b513650dd865bdb681cf4a4
https://doi.org/10.1096/fj.09-142398
https://doi.org/10.1096/fj.09-142398
Publikováno v:
Small. 6:239-246
An efficient and safe delivery system for small interfering RNA (siRNA) is required for clinical application of RNA interfering therapeutics. Polyethyleneimine (PEI)-capped gold nanoparticles (AuNPs) are successfully manufactured using PEI as the red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::443e9252aef65e7b3c573bd7ad04368d
https://doi.org/10.1002/smll.200901513
https://doi.org/10.1002/smll.200901513