Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Pei Rong Ding"'
Autor:
Youwen Qin, Xin Tong, Wei-Jian Mei, Yanshuang Cheng, Yuanqiang Zou, Kai Han, Jiehai Yu, Zhuye Jie, Tao Zhang, Shida Zhu, Xin Jin, Jian Wang, Huanming Yang, Xun Xu, Huanzi Zhong, Liang Xiao, Pei-Rong Ding
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The incidence of young-onset colorectal cancer (yCRC) has been increasing in recent decades, but little is known about the gut microbiome of these patients. Most studies have focused on old-onset CRC (oCRC), and it remains unclear whether CR
Externí odkaz:
https://doaj.org/article/42d593df93d840d1829cc0c6b2bcb11d
Autor:
Leen Liao, Jinghua Tang, Zhigang Hong, Wu Jiang, Yuan Li, Lingheng Kong, Kai Han, Zhenlin Hou, Chenzhi Zhang, Chi Zhou, Linjie Zhang, Qiaoqi Sui, Binyi Xiao, Weijian Mei, Jiehai Yu, Wanjun Yang, Zhizhong Pan, Pei-Rong Ding
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background For high-risk stageIImismatch repair deficient (dMMR) colon cancers, the benefit of adjuvant chemotherapy remains debatable. The principal aim of this study was to evaluate the prognostic value of high-risk factors and the effect
Externí odkaz:
https://doaj.org/article/7f3dac0f84c64da18d818885beac25b2
Autor:
De-Shen Wang, Chao Ren, Shan-Shan Li, William Pat Fong, Xiao-Jun Wu, Jian Xiao, Bin-Kui Li, Yun Zheng, Pei-Rong Ding, Gong Chen, Miao-Zhen Qiu, Zhi-Qiang Wang, Feng-Hua Wang, Hui-Yan Luo, Feng Wang, Xiao-Zhong Wang, Ling-Yun Wang, De-Jin Xie, Tao Chen, Li-Ren Li, Zhen-Hai Lu, Xiao-Hui Zhai, Tian-Shu Liu, Ying Yuan, Jia-Qi Chen, Qiong Tan, Zhi-Zhong Pan, De-Sen Wan, Rong Zhang, Yun-Fei Yuan, Rui-Hua Xu, Yu-Hong Li
Publikováno v:
PLoS Medicine, Vol 21, Iss 5, p e1004389 (2024)
BackgroundIt remains unclear whether intensification of the chemotherapy backbone in tandem with an anti-EGFR can confer superior clinical outcomes in a cohort of RAS/BRAF wild-type colorectal cancer (CRC) patients with initially unresectable colorec
Externí odkaz:
https://doaj.org/article/b9e6a45661f549378ef2d8ab851edf5e
Autor:
Qiaoqi Sui, Xi Zhang, Chao Chen, Jinghua Tang, Jiehai Yu, Weihao Li, Kai Han, Wu Jiang, Leen Liao, Lingheng Kong, Yuan Li, Zhenlin Hou, Chi Zhou, Chenzhi Zhang, Linjie Zhang, Binyi Xiao, Weijian Mei, Yanbo Xu, Jiayi Qin, Jian Zheng, Zhizhong Pan, Pei-Rong Ding
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Inflammatory conditions often affect colorectal cancer patients, and their effect on their ongoing treatment is a pressing medical question. Here authors show that inflammation interferes with local anti-tumour immune response and inhibits response t
Externí odkaz:
https://doaj.org/article/355b897d848f4ea8972b395f79905281
Autor:
Qiao-Xuan Wang, Shu Zhang, Wei-Wei Xiao, Cheng-Jing Zhou, Hui Chang, Zhi-Fan Zeng, Pei-Qiang Cai, Zhen-Hai Lu, Gong Chen, Pei-Rong Ding, Zhi-Zhong Pan, Xiao-Jun Wu, Yuan-Hong Gao
Publikováno v:
Radiation Oncology, Vol 17, Iss 1, Pp 1-10 (2022)
Abstract Background High dose chemoradiotherapy offers a curative chance for patients with rectal cancer that are unfit or unwilling to undergo surgical resection, yet its long-term survival and functional outcomes have been rarely investigated. Meth
Externí odkaz:
https://doaj.org/article/810bfbd66f154df0bfa9b9d30e71395e
Autor:
Qi Zhao, Feng Wang, Yan-Xing Chen, Shifu Chen, Yi-Chen Yao, Zhao-Lei Zeng, Teng-Jia Jiang, Ying-Nan Wang, Chen-Yi Wu, Ying Jing, You-Sheng Huang, Jing Zhang, Zi-Xian Wang, Ming-Ming He, Heng-Ying Pu, Zong-Jiong Mai, Qi-Nian Wu, Renwen Long, Xiaoni Zhang, Tanxiao Huang, Mingyan Xu, Miao-Zheng Qiu, Hui-Yan Luo, Yu-Hong Li, Dong-Shen Zhang, Wei-Hua Jia, Gong Chen, Pei-Rong Ding, Li-Ren Li, Zheng-Hai Lu, Zhi-Zhong Pan, Rui-Hua Xu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The ChangKang (Heathy Bowel) project was established to collect molecular and clinical information of a thousand Chinese colorectal cancer patients. Here, the authors present the genomic landscape of the ChangKang cohort and find a subgroup of patien
Externí odkaz:
https://doaj.org/article/ee0548bf4a574cba8d5b0964a7e38b91
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Colorectal cancers (CRCs) with high microsatellite instability (MSI-H) and deficient mismatch repair (dMMR) show molecular and clinicopathological characteristics that differ from those of proficient mismatch repair/microsatellite stable CRCs. Despit
Externí odkaz:
https://doaj.org/article/a50dcca7282442fea5d8daf3b60b66e2
Autor:
Lian-Jing Cao, Xiao-Lin Peng, Wen-Qiong Xue, Rong Zhang, Jiang-Bo Zhang, Ting Zhou, Zi-Yi Wu, Gai-Rui Li, Tong-Min Wang, Yong-Qiao He, Da-Wei Yang, Ying Liao, Xia-Ting Tong, Fang Wang, Ke-Xin Chen, Shi-Hong Zhang, Li-Qing Zhu, Pei-Rong Ding, Wei-Hua Jia
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background Colorectal cancer (CRC) is the leading cause of cancer death worldwide. Screening is a confirmed way to reduce the incidence and mortality rates of CRC. This study aimed to identify a fecal-based, noninvasive, and accurate method
Externí odkaz:
https://doaj.org/article/06320bcb449f4031ba1848783e979ddc
Autor:
Wu Jiang, Wei-Jian Mei, Shuo-Yu Xu, Yi-Hong Ling, Wei-Rong Li, Jin-Bo Kuang, Hao-Sen Li, Hui Hui, Ji-Bin Li, Mu-Yan Cai, Zhi-Zhong Pan, Hui-Zhong Zhang, Li Li, Pei-Rong Ding
Publikováno v:
EBioMedicine, Vol 81, Iss , Pp 104120- (2022)
Summary: Background: We aimed to develop a deep learning (DL) model to predict DNA mismatch repair (MMR) status in colorectal cancers (CRC) based on hematoxylin and eosin-stained whole-slide images (WSIs) and assess its clinical applicability. Method
Externí odkaz:
https://doaj.org/article/7c458154060c42e6a8afef4581087e25
Autor:
Shao-Qing Niu, Rong-Zhen Li, Yan Yuan, Wei-Hao Xie, Qiao-Xuan Wang, Hui Chang, Zhen-Hai Lu, Pei-Rong Ding, Li-Ren Li, Xiao-Jun Wu, Zhi-Fan Zeng, Wei-Wei Xiao, Yuan-Hong Gao
Publikováno v:
Radiation Oncology, Vol 16, Iss 1, Pp 1-9 (2021)
Abstract Background Patients with locally advanced sigmoid colon cancer (LASCC) have limited treatment options and a dismal prognosis with poor quality of life. This retrospective study aimed to further evaluate the feasibility and efficacy of neoadj
Externí odkaz:
https://doaj.org/article/eabb07d2cbf1418b91ee4c6f2248a570