Radiobiological Aspects of FLASH Radiotherapy

Autor: Eline Hageman, Pei-Pei Che, Max Dahele, Ben J. Slotman, Peter Sminia

Publikováno v: Biomolecules, Vol 12, Iss 10, p 1376 (2022)

Radiotherapy (RT) is one of the primary treatment modalities for cancer patients. The clinical use of RT requires a balance to be struck between tumor effect and the risk of toxicity. Sparing normal tissue is the cornerstone of reducing toxicity. Adv

Externí odkaz: https://doaj.org/article/e2225a5bd6cc4f4b8ee067d7bc780e39

Tumor grafted - chick chorioallantoic membrane as an alternative model for biological cancer research and conventional/nanomaterial-based theranostics evaluation

Autor: Valerio Voliani, Pei Pei Che, Patrizia Sarogni, Peter Sminia, Ana Katrina Mapanao, Elisa Giovannetti

Publikováno v: Mapanao, A K, Che, P P, Sarogni, P, Sminia, P, Giovannetti, E & Voliani, V 2021, ' Tumor grafted-chick chorioallantoic membrane as an alternative model for biological cancer research and conventional/nanomaterial-based theranostics evaluation ', Expert Opinion on Drug Metabolism and Toxicology, vol. 17, no. 8, pp. 947-968 . https://doi.org/10.1080/17425255.2021.1879047

Introduction: Advancements in cancer management and treatment are associated with strong preclinical research data, in which reliable cancer models are demanded. Indeed, inconsistent preclinical findings and stringent regulations following the 3Rs pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2cd71a382fa11aafddcc446e00a01ca
https://research.vumc.nl/en/publications/543dd1a2-6c6a-4b22-88ab-8a12d599ab69

Role of c-MET inhibitors in overcoming drug resistance in spheroid models of primary human pancreatic cancer and stellate cells

Autor: Btissame El Hassouni, Stefano Coppola, Pei Pei Che, Giulia Mantini, Matthias Löhr, Elisa Giovannetti, Niccola Funel, Mark Buijs, Godefridus J. Peters, Thomas Schmidt, Omidreza Firuzi, Amir Avan, Rainer Heuchel, Ilaria Carnevale, Luciano Saso

Publikováno v: Firuzi, O, Che, P P, el Hassouni, B, Buijs, M, Coppola, S, Löhr, M, Funel, N, Heuchel, R, Carnevale, I, Schmidt, T, Mantini, G, Avan, A, Saso, L, Peters, G J & Giovannetti, E 2019, ' Role of c-MET inhibitors in overcoming drug resistance in spheroid models of primary human pancreatic cancer and stellate cells ', Cancers, vol. 11, no. 5, 638 . https://doi.org/10.3390/cancers11050638
Cancers, 11(5):638. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers
Cancers, 11(5), 638. MDPI
Cancers, Vol 11, Iss 5, p 638 (2019)
Volume 11
Issue 5

Pancreatic stellate cells (PSCs) are a key component of tumor microenvironment in pancreatic ductal adenocarcinoma (PDAC) and contribute to drug resistance. c-MET receptor tyrosine kinase activation plays an important role in tumorigenesis in differe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::251399fa85971da2170f85f2e11abbce
https://research.vumc.nl/en/publications/d7fe9129-9bc6-4f81-b1f1-18e41e367ed4

Urinary podocyte microparticles are associated with disease activity and renal injury in systemic lupus erythematosus

Autor: Jian Lu, Ze Bo Hu, Pei Pei Chen, Chen Chen Lu, Jia Xiu Zhang, Xue Qi Li, Ben Yin Yuan, Si Jia Huang, Kun Ling Ma

Publikováno v: BMC Nephrology, Vol 20, Iss 1, Pp 1-9 (2019)

Abstract Background New non-invasive biomarkers are demanded to identify renal damage in various autoimmune-associated kidney diseases. Glomerular podocyte damage mediated by systemic lupus erythematosus (SLE) plays an important role in the pathogene

Externí odkaz: https://doaj.org/article/09f940b878d14a3c97f9fdaaefdd501c

Five Elements of Music Therapy Research on the Influence of Emotion and Meridian

Autor: Pei Pei Cheng, 鄭蓓蓓

95
70% to 90% diseases are caused from mixture of emotions and sensory pleasures and pressure. To contemporary people, the pressure is omnipresent. According to World Health Organization (WHO) recognizing, there are more than 80 types of physica

Externí odkaz: http://ndltd.ncl.edu.tw/handle/78891143725549009069