Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Pei Juan Lu"'
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0278711 (2022)
Breast cancer is heterogenous in development and cell population with prognoses being highly dependent on numerous factors from driving mutations, biomarker expression and variation in extracellular environment, all affecting response to therapies. R
Externí odkaz:
https://doaj.org/article/23c6b1dfa828407f8f9b5f3a9d45fb10
Autor:
Bo Wu, Morgan Drains, Sapana N Shah, Pei Juan Lu, Victoria Leroy, Jessalyn Killilee, Raegan Rawls, Jason D Tucker, Anthony Blaeser, Qi Long Lu
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0278482 (2022)
Limb Girdle Muscular Dystrophy 2I (LGMDR9) is one of the most common LGMD characterized by defects in glycosylation of α-dystroglycan (matriglycan) resulting from mutations of Fukutin-related protein (FKRP). There is no effective therapy currently a
Externí odkaz:
https://doaj.org/article/3daeaa8a81e74c3894089c5907bf8342
Autor:
Pei Juan Lu, Xiao Xiao, Chunping Qiao, Lei Xu, Qi Long Lu, Chi Hsien Wang, Derek J. Blake, Bin Xiao, Elizabeth Keramaris
Publikováno v:
Molecular Therapy. 21(10):1832-1840
Mutations in the FKRP gene are associated with a wide range of muscular dystrophies from mild limb-girdle muscular dystrophy (LGMD) 2I to severe Walker–Warburg syndrome and muscle-eye-brain disease. The characteristic biochemical feature of these d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7ebf568f23606fc780307645a27194
Publikováno v:
Advanced Materials Research. :3069-3073
The relationship between surface crack tip stress intensity factor and calculated parameters of pavement structure is discussed and finite element models based on the fracture mechanics theory is created. From the study in this paper, the following c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5bb96153536d6810d242bbc0727adaa
https://doi.org/10.4028/www.scientific.net/amr.250-253.3069
https://doi.org/10.4028/www.scientific.net/amr.250-253.3069
Autor:
Hiroyuki Awano, Jianbin Li, Carrie Bette Martin, Pei Juan Lu, Juan Li, Yi Dai, Xiao Xiao, Bin Xiao, Qi Long Lu, Chunxia Zhao, Zhenhua Yuan, Chunping Qiao, Chi-Hsien Wang
Mutations in fukutin-related protein (FKRP) gene cause a wide spectrum of disease phenotypes including the mild limb-girdle muscular dystrophy 2I (LGMD2I), the severe Walker-Warburg syndrome, and muscle-eye-brain disease. FKRP deficiency results in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f9244cac6d89b48878508ef401d247
Publikováno v:
The Journal of Cell Biology
Overexpression of the B cell leukemia/lymphoma-2 (bcl-2) gene has been shown to confer a survival advantage on cells by inhibiting apoptosis. In epithelia, the bcl-2 gene is also related to development and differentiation, and the protein is strongly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a4adefcf2421e4038b8780e7c2c59db
https://doi.org/10.1083/jcb.129.5.1363
https://doi.org/10.1083/jcb.129.5.1363
Autor:
Nicholas A. Wright, S. Gschmeissner, J. C. Reed, Pei-Juan Lu, Qi-Long Lu, M. A. Nasser Hajibagheri, S. Krajewski, Andrew M. Hanby, Joyce Taylor-Papadimitriou
Publikováno v:
Journal of Cell Science. 107:363-371
bcl-2 gene expression confers a survival advantage by preventing cells from entering apoptosis. In contrast to the previously described cytoplasmic localization of Bcl-2 in epithelial cells in vivo, in this study we have demonstrated, in a series of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36a4509602503f708d754cfacca4a83c
https://doi.org/10.1242/jcs.107.2.363
https://doi.org/10.1242/jcs.107.2.363
Autor:
Joy Burchell, Angela N. Barrett, Lucienne Cooper, Pei Juan Lu, Bente Madsen, Joyce Taylor-Papadimitriou, John Copier, Angelo G. Scibetta
Publikováno v:
International journal of cancer. 101(6)
The PLU-1 gene is expressed at the level of message in breast cancers and breast cancer cell lines and shows restricted expression in normal adult tissues with the exception of testis. The predicted protein sequence contains several domains, includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d6574f05a86c13e69b75f6debb23da9
https://pubmed.ncbi.nlm.nih.gov/12237901
https://pubmed.ncbi.nlm.nih.gov/12237901
Publikováno v:
Oncogene. 19(40)
Constitutive overexpression of c-erbB2 in the mammary epithelial cell line MTSV1-7 has been shown to result in epithelial-mesenchymal conversion, anchorage-independent growth and loss of organized morphogenesis in collagen. To elucidate the events le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a1b461331a16d12a87a4932020c16a
https://pubmed.ncbi.nlm.nih.gov/11030148
https://pubmed.ncbi.nlm.nih.gov/11030148
Publikováno v:
The Journal of biological chemistry. 271(30)
In this report, we have analyzed the function of two Sp1 sites present in the epithelium-specific MUC1 promoter. Using promoter-reporter gene (CAT) constructs, we found that mutagenesis of either of the Sp1 binding motifs at −576/−568 and −99/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cd7759da3d48092ea9392906750474b
https://pubmed.ncbi.nlm.nih.gov/8663395
https://pubmed.ncbi.nlm.nih.gov/8663395