Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Pei I Ho"'
Autor:
Ho-chia, Chen
Publikováno v:
Revue Bibliographique de Sinologie, 1962 Jan 01. 8, 172-172.
Externí odkaz:
https://www.jstor.org/stable/24608253
Autor:
Pei I Ho, David Ashline, Sirikarnt Dhitavat, Daniela Ortiz, Scott C Collins, Thomas B Shea, Eugene Rogers
Publikováno v:
Neurobiology of Disease, Vol 14, Iss 1, Pp 32-42 (2003)
Clinical studies suggest a relationship between folate deficiency and neurological and disorders including Alzheimer’s disease (AD). To investigate mechanisms underlying this association, we examined the consequences of folate deprivation on neuron
Externí odkaz:
https://doaj.org/article/8fc45ff50bf34b41b147efdbcf686c97
Autor:
Brian Webb, Dominick Casalena, John W. Daly, Douglas Hughes, Douglas S. Auld, Janaki Narahari, Evelina Cirbaite, Pei-i Ho, Vy Nguyen
Publikováno v:
Biochemistry. 57(31)
Luciferase-based reporter assays are powerful tools for monitoring gene expression in cells because of their ultrasensitive detection capacity and wide dynamic range. Here we describe the characterization and use of a luciferase reporter enzyme deriv
Autor:
Zhao B. Kang, Ophelia Ardayfio, Thomas M. Smith, W. Adam Hill, Douglas S. Auld, Iain M. Wallace, Ji-Hu Zhang, Scott Bowes, Pei-i Ho
Publikováno v:
SLAS Discovery. 19:651-660
Pilot testing of an assay intended for high-throughput screening (HTS) with small compound sets is a necessary but often time-consuming step in the validation of an assay protocol. When the initial testing concentration is less than optimal, this can
Autor:
Adam Hill, Zina Itkin, Douglas S. Auld, Damien MacDougall, Kim Yue, Mike Paolucci, Thomas M. Smith, Pei-i Ho
Publikováno v:
SLAS Discovery. 18:14-25
Compound sample preparation and delivery are the most critical steps in high-throughput screening (HTS) campaigns. Historically, several methods of compound delivery to assays have been used for HTS, including intermediate plates with prediluted comp
Autor:
Pei-i Ho, Yo-Jen Wang, S. Simon Wong, Boon-Khim Liew, M.T. Yang, Chik Patrick Yue, Yu-Tai Chia, R.T. Chang
Publikováno v:
IEEE Transactions on Electron Devices. 51:421-426
A predictive, physically based substrate resistance model for CMOS transistors operating at radio frequencies (RF) is described. This analytical model is scalable with transistor size and layout geometry. Measurement results confirm that the model ac
Autor:
Daniela Ortiz, Eugene Rogers, Pei I. Ho, Sirikarnt Dhitavat, David Ashline, Thomas B. Shea, Scott C. Collins
Publikováno v:
Neurobiology of Disease, Vol 14, Iss 1, Pp 32-42 (2003)
Clinical studies suggest a relationship between folate deficiency and neurological and disorders including Alzheimer's disease (AD). To investigate mechanisms underlying this association, we examined the consequences of folate deprivation on neuronal
Autor:
David Ashline, Eugene Rogers, Daniela Ortiz, Pei I. Ho, Scott C. Collins, Thomas B. Shea, Sirikarnt Dhitavat
Publikováno v:
Journal of Neurochemistry. 78:249-253
The cause of neuronal degeneration in Alzheimer's disease (AD) has not been completely clarified, but has been variously attributed to increases in cytosolic calcium and increased generation of reactive oxygen species (ROS). The beta-amyloid fragment
Autor:
Pramod Pandey, Brian Webb, Natasha Karassina, Lyne Breault, Keith V. Wood, Aaron J. McBride, Pei-i Ho, Douglas S. Auld, Adam Hill, Fred Harbinski, Kimberley Yue, Janaki Narahari
Publikováno v:
ACS chemical biology. 8(5)
Reporter gene assays (RGAs) are commonly used to measure biological pathway modulation by small molecules. Understanding how such compounds interact with the reporter enzyme is critical to accurately interpret RGA results. To improve our understandin
Autor:
Chad Vickers, Dejan Bojanic, Pei-i Ho, Y. Karen Wang, Ji-Hu Zhang, Brian K. Hubbard, Steven J. Stout, Thomas P. Roddy, W. Adam Hill, Christopher Horvath
Publikováno v:
Journal of biomolecular screening. 15(6)
Many attractive targets for therapeutic intervention are enzymes that catalyze biological reactions involving small molecules such as lipids, fatty acids, amino acid derivatives, nucleic acid derivatives, and cofactors. Some of the reactions are diff